A5076206380- Antibiotic Resistance in Bacteria
- COVID-19 Clinical Research Studies
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Antifungal resistance and susceptibility
- Inflammatory Bowel Disease
- Bacterial Identification and Susceptibility Testing
- Sepsis Diagnosis and Treatment
- Urinary Tract Infections Management
- Mycobacterium research and diagnosis
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Infections and bacterial resistance
- Pneumocystis jirovecii pneumonia detection and treatment
- Fungal Infections and Studies
- Vibrio bacteria research studies
- Vaccine Coverage and Hesitancy
- Infectious Diseases and Mycology
- Cervical Cancer and HPV Research
- Diagnosis and treatment of tuberculosis
- Ocular Infections and Treatments
Bursa Uludağ Üni̇versi̇tesi̇
2021-2024
Istanbul University-Cerrahpaşa
2021-2024
Ege University
2014-2023
Amsterdam University Medical Centers
2023
Istanbul University
2023
Kastamonu University
2020-2022
Izmir Institute of Technology
2020
Izmir University
2019
Ege Üniversitesi Tıp Fakültesi Hastanesi
2015-2018
The main aim of this study was to compare and analyze the effectiveness treatment regimens using ceftazidime/avibactam (CAZ/AVI) versus fosfomycin plus meropenem (FOS/MER) for managing bloodstream infections (BSI) or ventilator-associated pneumonia (VAP) caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) in critically ill patients. Between 4 January 2019, 16 July 2023, adult patients (≥18 years old) diagnosed with BSI VAP due culture confirmed CRKP ICU a tertiary care hospital were...
Abstract Background We aimed to compare the performance of carbapenemase classification in carbapenem-resistant Klebsiella pneumoniae (CRKP) obtained using BD Phoenix CPO Detect panel (CPO panel) and Cepheid Xpert Carba-R assays. analyzed 55 CRKP strains from clinical specimens collected between November 2020 2022. The was used detect both antibiotic susceptibility phenotypic classes, while employed identify KPC, NDM, VIM, OXA-48, IMP genes. Due limited availability molecular kits, we...
Our knowledge has gaps regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication levels and its association to severity of Coronavirus disease 2019 (COVID-19). The aim this study was investigate the SARS-CoV-2 viral load with serum biomarkers in COVID-19 patients.Viral determined via cycle threshold (Ct) values real-time reverse transcriptase-polymerase chain reaction (RT-PCR) 214 adult patients. Ct were compared clinical severity, biochemical hematological...
This paper aimed to evaluate the effects of COVID-19 pandemic on healthcare-associated infections (HAIs), antibiotic resistance and consumption rates in intensive care units (ICUs) a tertiary university hospital.Between 1 January 2018 31 December 2021, adult patients diagnosed with HAIs ICUs were investigated retrospectively. Patients divided into pre-pandemic (2018-2019) periods (2020-2021). Antibiotic index was calculated via using formula (total dose (grams)/defined daily (DDD) x total...
Sepsis is a severe clinical syndrome owing to its high mortality. Quick Sequential Organ Failure Assessment (qSOFA) score has been proposed for the prediction of fatal outcomes in sepsis emergency departments. Due low predictive performance qSOFA score, we propose modification by adding age. We conducted multicenter, retrospective cohort study among regional referral centers from various regions country. Participants recruited data patients admitted departments and obtained diagnosis...
Carbapenem-resistant Klebsiella pneumoniae (CPKP) infections seriously threaten global public health. The main objective of this study was to assess the in-vitro synergistic activity ceftazidime–avibactam (CZA) in combination with colistin (COL), amikacin (AK), gentamicin (GEN), and fosfomycin (FOS) against CPKP isolates. secondary goal determine antibiotic susceptibility performance BD Phoenix. OXA-48 (49.1%) predominant carbapenemase, followed by KPC (29.1%). We used broth microdilution...
In this study, we aimed to investigate retrospectively the patients with carbapenem-resistant Enterobacteriaceae urinary tract infections (UTIs) in terms of demographic findings, antibiotic sensitivity patterns and clinical features along treatment options. This study was performed at a tertiary-care educational university hospital. Adult (>18 years old) diagnosed culture proven UTI due Klebsiella pneumoniae (between December 2016 2017) were included study. Antimicrobial susceptibility...
In this study it was aimed to evaluate the prognostic factors for geriatric patients with confirmed COVID-19 in a tertiary-care hospital at Kastamonu region of Turkey.Patients (≥65-year-old) who had PCR positivity between March 2020 and April our center were recorded retrospectively. A p value less than 0.05 considered significant. Ethical committee approval given from Bolu University decision number 2020/176.There total 100 (44% female). In-hospital mortality as 7%. univariate analysis 1...
Anaplasmosis (Human Granulocytic Anaplasmosis, HGA), is a disease caused by Anaplasma phagocytophilum but also formerly known as Ehrlichia and equi. We present 57-year-old male diagnosed with systemic HGA lung involvement, who had lived in Benin. A possible tick bite been reported his history. There was dramatic response to treatment.
Determining prognostic factors in patients with coronavirus disease (COVID-19) can have great impact on treatment planning and follow-up strategies. Herein, we aimed to evaluate clinical scores for confirmed COVID-19 a tertiary-care hospital the Bursa region of Turkey.Patients who had been diagnosed microbiologically and/or radiologically between March October 2020 university were enrolled retrospectively. Adult (≥ 18 years) spectrum moderate, severe, or critical illness included. The...
In this paper, we present a 69 years old diabetic patient with mucormycosis who was succesfully treated liposomal amphotericin B (LAMB), posaconazole and deferasirox despite having no adequate surgery. There relapse on 6 month post-treatment follow-up. We conclude that combination of antifungal antibiotics may be successful in the salvage therapy especially patients. J Microbiol Infect Dis 2016;6(1): 32-35 Key words: mucormycosis, treatment, diabetes mellitus, mucorales
Candida species are among the most important causes of hospital acquired blood borne infections, and with high rates mortality morbidity, these infections still a major problem today. History gastrointestinal surgery, administration total parenteral nutrition and/or wide spectrum antibiotics immune suppression following organ transplantations considered serious risk factors for infections. This study aimed to evaluate patients from our general surgery department diagnosed candidemia; by...
ÖZMerkezi sinir sistemi (MSS) enfeksiyonları doğru tanı ve tedavi sağlanamadığında ciddi sonuçlara neden olabilmektedir.Olası etiyolojik patojenlerin geniş spektrumu MSS enfeksiyonlarının tanısını zorlaştırmaktadır
Data in the literature on use of ceftazidime-avibactam (CAZ-AVI) carbapenem-resistant Klebsiella pneumoniae bloodstream infections (CRKP-BSIs) are limited especially OXA-48 (Oxacillinase-48) predominant regions. Our study aimed to evaluate effect CAZ-AVI outcomes CRKP-BSIs Turkey, where is endemic. A multicenter retrospective observational was conducted between January 2017 and September 2021. The effects clinical treatment characteristics 30-day mortality relapse were analyzed. Predictors...
Abstract Corticosteroids are commonly used in lymphoma patients, and findings favor of esophageal involvement 18F‐FDG PET‐CT should be considered suspicious definitely confirmed by biopsy. We describe a 58‐year‐old lady with diffuse large B‐cell central nervous system having an increased metabolism the distal esophagus PET/CT, which was consistent candidiasis, most probably due to prolonged use dexamethasone. Esophageal candidiasis can misdiagnosed as malignancy high SUVmax may lead...
Abstract Background Systemic steroid use, and IBD itself, both have negative effect on bone mineral density. Budesonide is a synthetic with high topical glucocorticoid activity low systemic bioavailability. When compared to steroids, the frequency of side effects budesonide appears be quite low, however, there no documented report about long term use BMD in patients. We also do not know other potential use. In this study, we aimed evaluate its’ effects, Methods retrospectively reviewed files...
Abstract Our study aimed to detect carbapenem-resistant Klebsiella pneumoniae (CRKP) and/or Escherichia coli in perianal swab samples, exploring their link bloodstream infections (BSIs) a tertiary-care university hospital. CRKP-related BSIs ranged from 3.7% 9.58%, emphasizing the need understand local risk factors for effective infection control.
Stenotrophomonas maltophilia is a gram-negative bacterium that can cause hospital infections and outbreaks within hospitals. This study aimed to evaluate an outbreak of maltophilia, caused by ready-to-use commercial syringes containing liquid lithium heparin for arterial blood gas collection in university hospital.
This study- a secondary analysis of data from randomized, observer-blinded, non-inferiority study among volunteers between 18–55 y old in Türkiye- evaluated the impact previous SARS-CoV-2 infection before first dose inactive TURKOVAC on post-vaccine local and systemic adverse events (AEs) comparing with CoronaVac. Of 1266 participants analyzed, 27.7% had COVID-19 history. Local AEs were observed 37.3% 39% participants. The frequency was slightly higher 30 minutes 24 hours history; none...
Background: In this study it was aimed to evaluate the efficacy and timing with technique of source control for subgroup septic shock (SS) patients intraabdominal infections (IAI) in a tertiary-care educational hospital. Methods: Patients who had SS IAI consulted by Infectious Diseases consultants between December 2013 October 2022 our centre were analyzed retrospectively. Results: A total number 390 included. Overall day-30 mortality (OMM) 42.5% on day 3 while 14 30 rates 63.3% 71.3%,...
We have previously shown that CRP < 2.9 mg/L is a better predictor of endoscopic remission (ER) than 5 in ulcerative colitis (UC). Here, we prospectively evaluate and FCP cut-offs compare them predicting ER histological (HR) UC.