A5063697539- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Antibiotic Use and Resistance
- Infection Control and Ventilation
- Antibiotic Resistance in Bacteria
- COVID-19 and healthcare impacts
- Vaccine Coverage and Hesitancy
- Mosquito-borne diseases and control
- COVID-19 epidemiological studies
- Neutropenia and Cancer Infections
- Vector-borne infectious diseases
- Heparin-Induced Thrombocytopenia and Thrombosis
- Long-Term Effects of COVID-19
- Streptococcal Infections and Treatments
- Polyomavirus and related diseases
- Bacterial Identification and Susceptibility Testing
- Infection Control in Healthcare
- Parasitic Infections and Diagnostics
- Stress Responses and Cortisol
- Travel-related health issues
- SARS-CoV-2 detection and testing
- Vibrio bacteria research studies
- Pituitary Gland Disorders and Treatments
- Immune cells in cancer
Erciyes University
2019-2024
Ege University
2024
Kayseri Eğitim ve Araştırma Hastanesi
2023
Office of Infectious Diseases
2021
Erciyes Üniversitesi Tıp Fakültesi Hastaneleri
2021
Bozok Universitesi
2020
Although coronavirus disease 2019 (COVID-19) mainly involves the lungs, it also affects many systems. The hypothalamic/pituitary axis is vulnerable to hypoxia, hypercoagulation, endothelial dysfunction and autoimmune changes induced by COVID-19 infection. Given that there no extensive investigation on this issue, we investigated pituitary functions three seven months after acute Forty-three patients diagnosis of infection 11 healthy volunteers were included in study. In addition basal...
Abstract Background The core components (CCs) of infection prevention and control (IPC) from World Health Organization (WHO) are crucial for the safety quality health care. Our objective was to examine level implementation WHO (IPC CC) in a developing country. We also aimed evaluate care-associated infections (HAIs) antimicrobial resistance (AMR) intensive care units (ICUs) association with implemented IPC CCs. Methods Members Turkish Infectious Diseases Clinical Microbiology Specialization...
The prevalence of hospital-acquired infections caused by carbapenem-resistant gram-negative bacteria (CRGNB) is increasing worldwide. Several risk factors have been associated with such infections. present study aimed to identify and determine the mortality rates CRGNB in intensive care units.
Development of safe and effective vaccine options is crucial to the success fight against COVID-19 pandemic. Herein, we report interim safety immunogenicity findings phase 1&2 trials ERUCoV-VAC, an inactivated whole virion SARS-CoV-2 vaccine.Double-blind, randomised, single centre, 1 2 included seronegative healthy adults aged 18-55 years (18-64 in 2). All participants, except first 4 who received ERUCoV-VAC 3 μg or 6 unblinded monitored for 7 days purposes, were assigned receive two...
ÖZSıtma, dünya genelinde olgu sayısı ve ölüm oranı dikkate alındığında küresel bir halk sağlığı sorunu olmaya devam etmektedir
Various clinical outcomes, reinfections, vaccination programs, and antibody responses resulted from the COVID-19 pandemic. This study investigated time-dependent changes in SARS-CoV-2 infected and/or vaccinated unvaccinated individuals to provide insights into spike nucleocapsid antibodies, which fluctuate during infectious non-infectious states. cohort was carried out at Ege University Faculty of Medicine hospital İzmir (western Turkey) Erciyes Kayseri (central between December 2021 January...
Vaccine-induced immunity wanes over time and warrants booster doses. We investigated the long-term (32 weeks) immunogenicity safety of a third, homologous, open-label dose TURKOVAC, administered 12 weeks after completion primary series in randomized, controlled, double-blind, phase 2 study. Forty-two participants included analysis were evaluated for neutralizing antibodies (NAbs) (with microneutralization (MNT50) focus reduction (FRNT50) tests), SARS-CoV-2 S1 RBD (Spike Receptor Binding...
The ongoing COVID-19 pandemic poses a significant threat to human health. Many hypotheses regarding pathogenesis have been proposed and are being tried be clarified by experimental clinical studies. This study aimed reveal the roles of innate immune system modulator GAS6/sAXL pathway, endothelial dysfunction markers vascular growth factor (VEGF) hypoxia-inducible (HIF)-1α, antiviral effective TRIM25 TRIM56 proteins in COVID-19. included 55 patients with 25 healthy individuals. serum levels...
Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has been appeared first in China since December 2019. Transmission of SARS-CoV-2 occurs primarily with droplets through coughing and sneezing also inhalation aerosolized secretions, which travel, remain suspended air longer.Since early stages outbreak, COVID-19 cases have described healthcare workers (HCWs). However, stages, may be asymptomatic. This lead to incorrect diagnosis or...
In December 2019, Wuhan city, the capital of Hubei province in China, became center an outbreak pneumonia unknown cause. By Jan 7, 2020, Chinese scientists had isolated a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; previously known as 2019-nCoV), from these
Cerebral toxoplasmosis is a rare but often life-threatening infection after hematopoietic stem cell transplantation (HSCT). In such cases, early diagnosis and initiation of treatment are vital. We describe case cerebral in patient who underwent HSCT for acute myeloid leukemia. Infection was diagnosed with polymerase chain reaction (PCR) test cerebrospinal fluid cranial magnetic resonance imaging scan. The treated trimethoprim-sulfamethoxazole clindamycin combination. However, she died from...
This study aimed to determine the risk factors of infectious diarrhea in patients undergoing chemotherapy or hematopoietic stem cell transplantation for hematological malignancies.
This study- a secondary analysis of data from randomized, observer-blinded, non-inferiority study among volunteers between 18–55 y old in Türkiye- evaluated the impact previous SARS-CoV-2 infection before first dose inactive TURKOVAC on post-vaccine local and systemic adverse events (AEs) comparing with CoronaVac. Of 1266 participants analyzed, 27.7% had COVID-19 history. Local AEs were observed 37.3% 39% participants. The frequency was slightly higher 30 minutes 24 hours history; none...
Crimean-Congo hemorrhagic fever (CCHF) is one of the common causes tick-borne infections. The study aims to report a case female patient with severe CCHF pulmonary embolism.A 61-year-old woman admitted emergency department complaints high fever, nausea, and weakness. was dealing animal husbandry had tick bite history. At laboratory findings, bicytopenia, abnormal liver function tests, elevated coagulation parameters were observed. Real-time plymerase chain reaction confirmed diagnosis CCHF....
Amaç: Kan dolaşımı infeksiyonu bütün dünyada sepsisle ilişkili önemli morbidite ve mortalitenin başlıca nedenlerinden biridir.Bu geriye dönük çalışmada fatal seyirli erişkin hastalardaki kan kültürü pozitifliğinin araştırılması; sonuçlarının, bakteriyemi etyolojisinin hastaların uygun antimikrobiyal tedaviyi alıp almadıklarının değerlendirilmesi
Introduction: BK polyomavirus (BKPyV) infections are an important cause of morbidity and mortality after hematopoietic stem cell transplantation (HSCT). The aim the study was to assess clinical characteristics BKPyV HSCT. Materials Methods:The conducted in adult HSCT clinics a tertiary hospital central Turkey between January 2017 December 2019.Results: A total 54 patients with were retrospectively evaluated disease seen 24 (44%).Hemorrhagic cystitis (HC) 19 (79.2%) these patients.The median...
Background: Safe and effective vaccine options is crucial to fight against COVID-19 pandemic. We report interim safety immunogenicity findings of the phase 1&2 trials ERUCoV-VAC, an inactivated whole virion SARS-CoV-2 vaccine. Methods: Double-blind, randomised, single centre, included seronegative healthy adults aged 18-55 years (18-64 in 2). Participants, were assigned receive two intramuscular doses ERUCoV-VAC 3µg or 6µg placebo 21 days apart (28 2) via computer-generated randomisation....