- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Bee Products Chemical Analysis
- Hepatitis B Virus Studies
- Essential Oils and Antimicrobial Activity
- Pneumonia and Respiratory Infections
- Antibiotics Pharmacokinetics and Efficacy
- Hepatitis C virus research
- Immunodeficiency and Autoimmune Disorders
- Urinary Tract Infections Management
- Yeasts and Rust Fungi Studies
- Liver Disease Diagnosis and Treatment
- Infective Endocarditis Diagnosis and Management
- Ocular Diseases and Behçet’s Syndrome
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Pharmaceutical and Antibiotic Environmental Impacts
- Vibrio bacteria research studies
- Cytomegalovirus and herpesvirus research
- Multiple Myeloma Research and Treatments
- Brucella: diagnosis, epidemiology, treatment
Erciyes University
2008-2025
Ministry of Health
2018
Kayseri Eğitim ve Araştırma Hastanesi
2012-2017
Office of Infectious Diseases
2015
Czech Academy of Sciences, Institute of Microbiology
2015
Drone larvae (DL) has many biological activities thanks to the bioactive components it contains, but there are very few studies on its antimicrobial activity. The aim of this research was determine antifungal activity DL (raw and lyophilised) water ethanol extracts against fluconazole (FLU) sensitive resistant yeast strains. 87 fungal strains obtained from clinical samples were identified by phenotypic molecular methods, broth microdilution test used for All had ethanolic extract lyophilised...
Interdigital foot infections are mostly caused initially by dermatophytes, yeasts and less frequently bacteria. Erythrasma Corynebacterium minutissimum can be confused with superficial mycoses. The aim of the study was to determine prevalence etiologic agents mycoses frequency in interdigital infections. All samples obtained from 121 patients were examined directly use 20% potassium hydroxide mounts Gram stain under microscope cultured on Sabouraud's dextrose agar plates. In identification...
Background : Due to the failure of available antifungal agents in treatment candidemia and toxic activities these drugs, a lot researches are being conducted develop new nontoxic effective for optimal control fungal pathogens. The aim this study is evaluate vitro activity propolis against yeasts isolated from blood cultures intensive care unit patients. Methods Seventy‐six strains were included study. propolis, fluconazole (FLU), itraconazole (ITR) was investigated by microdilution broth...
The aim of study was to investigate the virulence factors phospholipase, proteinase, esterase production and biofilm formation in Candida species isolated from patients with candidemia, assess their relationship genotypes derived after repetitive sequence-based polymerase chain reaction (rep-PCR) fingerprinting.Fifty-two strains were identified level according conventional methods sequencing. DiversiLab system used for genotyping. Enzyme activities evaluated using microbiological methods.The...
When the problem with carbapenem-resistant Enterobacteriaceae (CRE) increases, older antimicrobial agents such as colistin and fosfomycin are used for treatment of these infections. In this study, broth microdilution method agar dilution were a total 147 multidrug-resistant (MDR) or extensively drug-resistant (XDR) strains CRE. The study included Klebsiella pneumoniae (91.16%), Escherichia coli (7.48%), Enterobacter cloacae (0.68%), Serratia marcescens (0.68%). All produce various types...
Introduction Anti-rods and rings (anti-RR) antibodies have recently been described as a cytoplasmic pattern in IIF-based screening of autoantibodies on HEp-2 cells ICAP has named it AC-23. It is most frequently related to drug-induced antibody generation. This study aimed investigate the clinical significance AC-23 positivity its relevance diagnosis and/or follow-up associated diseases drug use. Methods A multicenter retrospective was conducted among 10 hospitals from six different provinces...
Objectives. The microscopic analysis of urine is essential for the diagnosis patients with urinary tract infections. Quantitative culture 'gold standard' method definitive urinary-tract infections, but it labor-intensive, time consuming, and does not provide same-day results. aim this study was to evaluate analytical diagnostic performance FUS200 (Changchun Dirui Industry, China), a new sedimentation analyzer in comparison as reference method. Methods. We evaluated 1000 samples, submitted...
Purpose: To obtain aqueous humor and tear fluid samples during cataract surgery of the hepatitis C virus (HCV)-antibody-positive patients in order to analyze them for HCV RNA compare these measurements with serum levels.Methods: Twenty-nine anti-HCV-positive were included this study. viral load levels determined by commercial real-time polymerase chain reaction system. Antibodies screened enzyme-linked immunosorbent assay (ELISA) using anti-HCV test kit.Results: Log10 found be 6.00 ± 1.06...
SUMMARY OBJECTIVE: The aim of this study was to evaluate the demographic data, molecular epidemiology, and in vitro antifungal susceptibility results patients with Aspergillus isolated from various clinical specimens. METHODS: A total 44 strains were studied. definition invasive aspergillosis made according European Organization for Research Treatment Cancer/Invasive Fungal Infections Cooperative Group National Institute Allergy Infectious Diseases Mycoses Study (EORTC/MSG) criteria. Strains...
Abstract Objective In this study, we aimed to determine the prevalence of agents that cause superficial mycoses and clinical types in terms age gender our region were aimed. Methods Five hundred samples nails, skin with hair taken from 476 children adult patients pre‐diagnosed examined by direct microscopy cultural methods between October 2009 2010. Results Fungal elements determined 212 (42.4%) using microscopy. growth was detected 111 (22.2%) cultures same samples. It found most common...
Background: Mucormycosis is a rare, worldwide fungal infection with high mortality, which mostly affects immunocompromised patients. Compared to large parts of Asia, Europe, and the USA, information on clinical expression species distribution in mucormycosis Turkey limited. Objectives methods: The main aim this study was evaluate demographic features cases, identify isolates at level by using matrix-assisted laser desorption ionization-time flight mass spectrometry (MALDI-TOF), compare...
Objectives: Crimean–Congo hemorrhagic fever (CCHF) is a tick-borne zoonotic infection caused by Crimean Congo virus (CCHFV). The aim of the present study was to investigate association between blood neutrophil-to-lymphocyte ratio (NLR) and mean platelet volume (MPV) which are simple markers subclinical inflammation CCHF. We also investigated relationship these with coagulation parameters. Methods: Thirty-one suspected CCHF patients, who submitted Training Research Hospital, Kayseri, Turkey...
Hepatitis C virus (HCV) is an important cause of chronic liver disease. There are six genotypes and more than 80 subtypes HCV. The aim this study was to investigate the distribution HCV in Middle Anatolia Turkey, association with pre-treatment RNA viral load, serum transaminase levels, histopathological grade fibrosis.A total 160 patients (103 female, 57 male) hepatitis were retrospectively evaluated. level determined by commercial real time PCR method. positive sera genotyped Abbott Real...
Early detection of antibiotic susceptibility profile the isolates has critical importance in terms immediate beginning appropriate treatment and increasing success, such as meningitis, bacteriemia sepsis. In present study, it was aimed to compare results Quicolor (Salubris Inc., Massachusetts, USA) standard disk diffusion method.One hundred twenty three were included this study (80 Enterobacteriaceae, 15 Staphylococci 28 nonfermentative Gram-negative bacteria). Antibiotic clinical evaluated...
The colonization rate of Candida spp. reaches up to 80% in patients who reside intensive care units (ICUs) more than a week, and the mean development invasive disease is 10% colonized patients. Since candidiasis (IC) ICU presents with septic shock high mortality rate, rapid diagnosis treatment are crucial. aim this study was assess relationship between infection determination index (CI) score (CS) admitted at risk for IC likely benefit from early antifungal therapy. A total 80 (34 female, 46...