Hüsniye Şimşek

ORCID: 0000-0003-1723-5837
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Antibiotic Use and Resistance
  • Bacterial Identification and Susceptibility Testing
  • Antibiotics Pharmacokinetics and Efficacy
  • Infections and bacterial resistance
  • Probiotics and Fermented Foods
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Antimicrobial Resistance in Staphylococcus
  • Urinary Tract Infections Management
  • Bacillus and Francisella bacterial research
  • Bacteriophages and microbial interactions
  • Bacterial biofilms and quorum sensing
  • Pneumonia and Respiratory Infections
  • Pharmacovigilance and Adverse Drug Reactions
  • Escherichia coli research studies
  • Mycobacterium research and diagnosis
  • Nursing Diagnosis and Documentation
  • Burkholderia infections and melioidosis
  • Infective Endocarditis Diagnosis and Management
  • Infectious Diseases and Mycology
  • Vibrio bacteria research studies
  • Drug-Induced Adverse Reactions
  • Central Venous Catheters and Hemodialysis
  • Infant Nutrition and Health
  • Infant Health and Development

Ministry of Health
2013-2024

Ankara University
2021

Directorate of Health
2019

Public Health Department
2019

Antibiotic resistance is one of the most important public health problem and critical steps in preventing monitorization resistance. Local, regional global monitoring enables spread antibiotic to be understood more clearly. In this study, it was aimed evaluate results pilot study for establishment molecular-based carbapenem surveillance system Escherichia coli Klebsiella pneumoniae isolates investigate carbapenemase epidemiology Turkey. Hospitals (n= 28) from 26 different statistical level...

10.5578/mb.20124 article EN Mikrobiyoloji Bulteni 2021-01-27

When the problem with carbapenem-resistant Enterobacteriaceae (CRE) increases, older antimicrobial agents such as colistin and fosfomycin are used for treatment of these infections. In this study, broth microdilution method agar dilution were a total 147 multidrug-resistant (MDR) or extensively drug-resistant (XDR) strains CRE. The study included Klebsiella pneumoniae (91.16%), Escherichia coli (7.48%), Enterobacter cloacae (0.68%), Serratia marcescens (0.68%). All produce various types...

10.1556/030.65.2018.042 article EN Acta Microbiologica et Immunologica Hungarica 2018-11-07

In this study, the presence of genes responsible for pathogenicity and antibiotic resistance profile enterococci isolated from various foodstuffs animal origin was investigated. The percentage prevalence 54.1% (203/375) average count found to be 3.81 log cfu/ml-g. Species-specific primers revealed Enterococcus faecalis as predominant species carrying one or more virulence-associated traits efa, gelE, ace, esp agg genetic markers. Only E. faecium isolate (from milk) positive gene. Regarding...

10.1556/004.2017.044 article EN Acta Veterinaria Hungarica 2017-12-01

Background: Congenital heart diseases (CHD) are the most common birth defects. Necrotizing enterocolitis (NEC) is an important cause of morbidity and mortality in premature infants, probiotics can be used to protect NEC.Case report: We present a term infant with aortic coarctation who developed sepsis Lactobacillus rhamnosus GG after probiotic use, successfully treated ampicillin. The baby unfortunately died acute cardiac arrest on 90th day life.Conclusion: Probiotic-associated may develop...

10.1080/15513815.2021.1966144 article EN Fetal and Pediatric Pathology 2021-08-20

Background/aim: To have country-wide information about multidrug resistance (MDR) in isolates from community-acquired urinary tract infections (CAUTI) of Turkey, terms rates and useful options. Materials methods: We used a geocode standard, nomenclature territorial units for statistics (NUTS), total 1588 20 centres 12 different NUTS regions between March 2019 2020 were analysed. Results: Of the culture growths, 1269 (79. 9%) Escherichia coli 152 (9.6%) Klebsiella spp. Male sex, advanced age,...

10.55730/1300-0144.5641 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2023-01-01

Fixed drug eruption (FDE) is an unusual drug-related side effect that results in recurrent lesions whenever the causative drugs are used. FDEs usually occur as a single, sharply demarcated, round erythematous patch or plaque, occasionally with localized bullae. The most common offending agents include antimicrobials, nonsteroidal anti-inflammatory drugs, and antiepileptics. There some reports where contact dermatitis cutaneous vasculitis have been associated use of flurbiprofen. We present...

10.1177/0960327113489048 article EN Human & Experimental Toxicology 2013-05-23

Pozitif sinyal veren kan kültürü şişelerinden doğrudan tanımlama yapılarak sonuçların daha erken kliniğe bildirilmesinin mortalite ve morbidite üzerinde olumlu etkileri olduğu bildirilmektedir.Özellikle deterjanların kullanıldığı ekstraksiyon yöntemleri, pozitif şişelerden için kullanılmaktadır.Bu amaçla, özellikle saponin kullanımına dayalı geliştirilen "in-house" yöntemler literatürde yaygın olarak yer almaktadır.Bu çalışmada, deterjan bir madde olan Tween ® 80 kullanımı ile şişesinden...

10.5578/mb.69849 article TR Mikrobiyoloji Bulteni 2020-10-15

Stenotrophomonas maltophilia is a gram-negative bacterium that can cause hospital infections and outbreaks within hospitals. This study aimed to evaluate an outbreak of maltophilia, caused by ready-to-use commercial syringes containing liquid lithium heparin for arterial blood gas collection in university hospital.

10.1186/s13756-024-01410-8 article EN cc-by Antimicrobial Resistance and Infection Control 2024-05-20

Objective: Antimicrobial resistance is a growing problem worldwide, and to combat with this some measures should be taken.One of them analysis current situation National Resistance Surveillance System (NAMRSS) was established for purpose.The quality the data depends on participating laboratories performance, so there need an assessment in system.This study aimed analyse status antimicrobial susceptibility testing requirements.Methods: There were 77 selected NAMRSS throughout...

10.5505/turkhijyen.2018.89166 article EN Turkish Bulletin of Hygiene and Experimental Biology 2018-01-01

National Antimicrobial ResistanceSurveillance System (NAMRSS) was established aiming to determine and track the percentage of antimicrobial resistance in Turkey, order assure reliability system, an external quality assurance laboratory proficiency assessment performed September 2011, for first time.Methods: Four bacterial strains were sent 77 participating laboratories.The laboratories asked perform identification susceptibility tests (AST) according standard operating procedures NAMRSS...

10.5505/turkhijyen.2018.10437 article EN Turkish Bulletin of Hygiene and Experimental Biology 2018-01-01

<title>Abstract</title> Background <italic>Stenotrophomonas maltophilia</italic> is a gram-negative bacterium that can cause hospital infections and outbreaks within hospitals. This study aimed to evaluate an outbreak of maltophilia</italic>, caused by ready-to-use commercial syringes containing liquid lithium heparin for arterial blood gas collection in university hospital. Methods Upon detecting increase growth cultures between 15.09.2021 19.11.2021, analysis case-control (52 patients the...

10.21203/rs.3.rs-3764243/v1 preprint EN cc-by Research Square (Research Square) 2023-12-20

Establishment of sustainable and evidence-based surveillance systems are recommended for prevention microbial resistance by the World Health Organization (WHO). As a necessity these systems, participants to implement an external quality assessment (EQA) program. In this scope, National Antimicrobial Resistance Surveillance System (NARSS) has been established within Public Institute Turkey (PHIT) in our country since 2011. scope surveillance, NARSS EQA program implemented cycle per year four...

10.5578/mb.57421 article EN Mikrobiyoloji Bulteni 2017-07-10

Abstract The synergistic activity of eravacycline in combination with colistin on carbapenem-resistant A.baumannii (CRAB) isolates was evaluated this study. Minimum inhibitory concentrations (MICs) and were determined by the broth microdilution method. MICs values ranged between 1 to 4 mg 0,5 128 mg/L for colistin, respectively. In-vitro synergy using chequerboard methodology. Synergistic found 10 % strains, additive effect 20 %. No antagonism detected. Similar also observed resistant CRAB...

10.1101/552547 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2019-02-19

Objective: Antibiotic resistance is one of the most significant problems human-animal and environmental ecosystems. It crucial to establish integrated surveillance systems monitor for management antibiotic resistance. Standardization data obtained from various disciplines critical point in enhancing quality. To realize this objective, a common susceptibility testing training program was prepared performed professionals standardize be human, animal, sectors our country. Method: A total 48...

10.5222/tmcd.2021.27676 article EN Türk Mikrobiyoloji Cemiyeti Dergisi 2021-01-01
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