A5059871144- Congenital Heart Disease Studies
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
- Vascular anomalies and interventions
- Coronary Artery Anomalies
- Tracheal and airway disorders
- Congenital Diaphragmatic Hernia Studies
- Pericarditis and Cardiac Tamponade
- Cardiac Structural Anomalies and Repair
- Cardiovascular Issues in Pregnancy
- Cardiovascular and Diving-Related Complications
- Streptococcal Infections and Treatments
- Cardiovascular Function and Risk Factors
- Central Venous Catheters and Hemodialysis
- Kawasaki Disease and Coronary Complications
- Cardiac Valve Diseases and Treatments
- Cardiomyopathy and Myosin Studies
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Inflammasome and immune disorders
- Cardiac tumors and thrombi
- Cardiovascular Syncope and Autonomic Disorders
- Mechanical Circulatory Support Devices
- Ultrasound in Clinical Applications
- Cardiovascular Effects of Exercise
Memorial Ankara Hospital
2023-2025
Ministry of Health
2015-2024
Dr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi
2011-2023
Sağlık Bilimleri Üniversitesi
2018-2023
University of Health Science
2022-2023
University of Health Sciences
2023
Pediatrics and Genetics
2008-2021
Nature Conservation Centre
2016
Education Training And Research
2014
Boston Children's Hospital
2011-2013
The orphan nuclear receptor steroidogenic factor-1 (SF-1, NR5A1) regulates the transcription of multiple genes involved in steroidogenesis, reproduction, and male sexual differentiation. A heterozygous loss-of-function SF-1 mutation (G35E) has been described a patient with adrenal failure complete 46XY sex-reversal, indicating that haploinsufficiency this factor is sufficient to cause severe clinical phenotype. This P-box region DNA-binding domain markedly impairs binding most response...
Abstract Objective: Congenital heart diseases (CHD) are the most common causes of birth defects that have increased risk infections. Neonatal sepsis is a life-threatening condition and early diagnosis can be life-saving. We aimed to evaluate potential role systemic immune-inflammatory index in neonatal sepsis. Methods: A retrospective cohort study was conducted on 166 newborns with who were admitted our hospital CHD between January 2017 June 2021. Haematological indices including...
Abstract This case report discusses a 1-year-old female with severe growth retardation and multiple congenital anomalies, including large patent ductus arteriosus interrupted inferior vena cava. Successful percutaneous closure was achieved via the azygos venous route, overcoming anatomical challenges highlighting importance of individualized procedural strategies in complex cases.
Cardiac rhabdomyoma is the most common primary cardiac tumor, considered to be a hamartoma of developing myocytes. associated with tuberous sclerosis complex (TSC) in 50-86% cases. Mutations TSC-1/TSC-2 genes result increased mammalian target rapamycin (mTOR) pathway activation responsible for hamartomatous lesions complex. Therapy mTOR inhibitors currently under investigation as treatment option tumors TSC. In this report we present case multiple symptomatic rhabdomyomas complex, deemed...
Cardiac dysfunction is a well-known consequence of diabetes mellitus. This study was designed to assess whether type 1 diabetic children and adolescents with good metabolic control have early echocardiographic signs subclinical left ventricular duration has any influence, using conventional nonconventional tools.A total 100 patients mellitus 80 gender- age-matched healthy controls were included. The cases underwent standard transthoracic echocardiography, tissue Doppler imaging,...
Abstract Background Kawasaki disease (KD) may cause cardiac and coronary complications. Since definite markers to accurately predict involvement is not present, we aimed analyze the role of hematological indices [neutrophil-to lymphocyte ratio (NLR), platelet-to (PLR), lymphocyte-to monocyte (LMR), mean platelet volume (MPV)-to (MPVLR)], prognostic nutritional index (PNI) systemic immune-inflammation (SII) in predicting KD. Patients The medical records 134 KD patients admitted between...
BackgroundNewborns with critical congenital heart disease (CCHD) increased pulmonary blood flow (PBF) are at high risk for congestive failure. In this study, we aimed to evaluate the presence and degree of edema in newborns CCHD using lung ultrasound (LUS) during perioperative period.MethodsProspective clinical trial, 44 newborn patients were evaluated prospective trial. LUS was repeatedly performed determine course period. simultaneously chest radiography (CXR), which main part patient...
The aim of this study was to assess the relation between plasma B-type natriuretic peptide (BNP) levels and right ventricular function evaluated by tissue Doppler imaging (TDI) in patients after repair tetralogy Fallot (ToF).Twenty-five with a mean age 14.1 +/- 4.4 years who underwent ToF at 4.9 5.1 enrolled study. control group consisted 29 healthy children 13.1 2.8 years. ventricle pulmonary regurgitation (PR) were assessed two-dimensional echocardiography color Doppler. Blood samples for...
Background This study focuses on determining concomitant persistent left superior vena cava ( SVC ) in patients with congenital heart disease CHD ). Methods Between 2005 and 2012, a total of 2.663 , 88 (3.3%) whom were diagnosed evaluated retrospectively. The demographic characteristics patients, clinical radiographic findings, echocardiography, cardiac catheterization, angiography results obtained from the patients’ records reviewed. Results median age was 9.5 months, 46 (52.3%) female....
Chest pain is the second most common reason for referral to paediatric cardiologists after benign heart murmurs. Aetiology frequently depends on non-cardiac reasons. In addition, individuals may experience chest which idiopathic or of unknown origin. The aim this study examine psychological symptoms in children and adolescents with medically unexplained pain.A total 76 patients (ages 8-18 years) were included study, who referred cardiology department complaint but did not have any detected...
To determine the frequency of congenital heart defects (CHD) in children with gastrointestinal malformations (GISM) and mortality rates patients GISM.Two hundred forty two consecutive GISM followed up Pediatric Surgery Clinics our hospital were examined for cardiovascular anomaly by Department Cardiology, CHD incidence was investigated examining records retrospectively. Chi-square test used statistical analysis data.Two system included study. Of 242 patients, 135 (55.8%) male 107 (44.2%)...
Anthracycline chemotherapeutic agents carry the well-recognised risk of cardiac toxicity. The aim this study was to determine long-term effect anthracycline chemotherapy on biventricular function in childhood cancer survivors using tissue Doppler imaging and two-dimensional speckle tracking echocardiography.The included 45 cancers 50 healthy age-matched control patients. Cardiac prospectively studied with conventional echocardiography, imaging, echocardiography after completion treatment....
The aim of the present study was to determine role toxic elements and trace in pathogenesis conotruncal heart defects by measuring their concentrations first meconium specimens affected newborns.Concentrations lead, cadmium, iron, zinc, copper were measured 1st-day that collected from 60 newborns with (Group I) 72 healthy II).The had statistically similar demographic clinical characteristics. When compared newborns, mean significantly higher (p=0.001 for each). In total, 51 normal karyotype....
This study assessed the early changes in regional and global systolic diastolic myocardial functions patients with familial Mediterranean fever without any cardiovascular symptoms using tissue Doppler strain rate echocardiography compared them to results of a control group.
Abstract Impairment of right ventricular functions, especially due to chronic pulmonary regurgitation (PR), is a well-known entity in patients with tetralogy Fallot (ToF) after repair. The aim this study was examine the relation between B-type natriuretic peptide (BNP) levels and dysfunction by cardiopulmonary exercise test (ET) repair ToF. Twenty-five mean age 14.1 ± 4.4 years at follow-up who underwent ToF 4.9 5.1 29 age- sex-matched healthy children 13.1 2.8 were enrolled study. Plasma...
Abstract Objective It is suggested that folic acid and/or multivitamins, taken periconceptionally, have a role in the prevention of many congenital anomalies. The aim this study was to determine serum micronutrient levels mother–infant pairs with CHD compared those healthy newborns and their mothers. Methods Serum acid, homocysteine, zinc, vitamin A, D, B 12 were measured from 108 (study group) 103 (control group). mothers’ also simultaneously. Results When newborns, for both maternal...
Background: Congenital heart diseases (CHD) are the most common birth defects. Necrotizing enterocolitis (NEC) is an important cause of morbidity and mortality in premature infants, probiotics can be used to protect NEC.Case report: We present a term infant with aortic coarctation who developed sepsis Lactobacillus rhamnosus GG after probiotic use, successfully treated ampicillin. The baby unfortunately died acute cardiac arrest on 90th day life.Conclusion: Probiotic-associated may develop...