Nilden Tuygun

ORCID: 0000-0002-5359-4215
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About
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Research Areas
  • Poisoning and overdose treatments
  • Cardiac Arrest and Resuscitation
  • Immunodeficiency and Autoimmune Disorders
  • Streptococcal Infections and Treatments
  • Respiratory viral infections research
  • Emergency and Acute Care Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Pneumonia and Respiratory Infections
  • Bacterial Infections and Vaccines
  • Neonatal Health and Biochemistry
  • Respiratory Support and Mechanisms
  • Epilepsy research and treatment
  • Drug-Induced Adverse Reactions
  • Congenital Diaphragmatic Hernia Studies
  • Foreign Body Medical Cases
  • Infectious Encephalopathies and Encephalitis
  • Neonatal Respiratory Health Research
  • Heme Oxygenase-1 and Carbon Monoxide
  • Disaster Response and Management
  • Neonatal and fetal brain pathology
  • Viral Infections and Immunology Research
  • Traumatic Ocular and Foreign Body Injuries
  • Sepsis Diagnosis and Treatment
  • Hematological disorders and diagnostics
  • Intestinal Malrotation and Obstruction Disorders

Sağlık Bilimleri Üniversitesi
2019-2025

University of Health Sciences
2022-2024

University of Health Science
2022-2024

Memorial Ankara Hospital
2022-2024

Ministry of Health
2012-2023

Dr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi
2009-2021

İstanbul Eğitim ve Araştırma Hastanesi
2013-2020

Sivas Cumhuriyet Üniversitesi
2020

Sivas State Hospital
2020

Türkiye Acil Tıp Derneği
2016-2017

Brucellosis constitutes a public health problem in Turkey. In endemic Brucella melitensis areas such as Turkey, children represent 20-25% of cases.Hospital records 90 with brucellosis admitted during 9 year period, 1997-2006, were evaluated retrospectively.Of patients, 27 (30%) female and 63 (70%) male (P < 0.05). Patients aged between 1 16 years age. The mean age was 9.02 +/- 3.59 years. Fifty-two patients (57.8%) from rural mode transmission consumption unpasteurized milk products 64...

10.1111/j.1442-200x.2008.02661.x article EN Pediatrics International 2008-09-01

Although the mechanism of Coronavirus disease 2019 (COVID-19) related liver damage in critically ill children is not well defined yet, it thought to be hyperinflammation phase (cytokine release). Here, we present a 40-day-old asymptomatic patient with isolated severe enzyme elevation associated COVID-19. A female was admitted our emergency department for screening after her mother diagnosed The patient’s vital signs and physical examination were normal on admission. Laboratory findings...

10.70852/tmj.1535245 article EN cc-by-nc Türk tıp dergisi. 2025-02-27

This is an observational epidemiological study to describe causes of bacterial meningitis among persons between 1 month and 18 y age who are hospitalized with suspected in 7 Turkish regions. covering 32% the entire population Turkey. We present here results from 2013 2014. A clinical case was defined according followings: any sign including fever, vomiting, headache, meningeal irritation children above one year fever without documented source, impaired consciousness, prostration seizures...

10.1080/21645515.2016.1209278 article EN Human Vaccines & Immunotherapeutics 2016-07-25

The aim of the present study was to identify epidemiological, clinical and laboratory features Crimean-Congo hemorrhagic fever (CCHF) virus infection in children.Fifty children infected with CCHF 2005-2010, hospitalized Dr Sami Ulus Maternity Children's Health Diseases Training Research Hospital Ankara, were included. All patients had positive IgM and/or polymerase chain reaction for virus.Of 50 patients, 19 female 31 male. Patients between 8 months 15 years age. majority (82%) a history...

10.1111/j.1442-200x.2011.03549.x article EN Pediatrics International 2011-12-22

Background: In April 2009 a novel strain of human influenza A, identified as H1N1 virus, rapidly spread worldwide, and in early June the World Health Organization raised pandemic alert level to phase 6. Herein we present largest series children who were hospitalized due infection Turkey. Methods: We conducted retrospective multicentre analysis case records involving with influenza-like illness, whom was diagnosed by reverse-transcriptase polymerase chain reaction assay, at 17 different...

10.3109/00365548.2011.598872 article EN Scandinavian Journal of Infectious Diseases 2011-08-23

Benign acute childhood myositis (BACM) is associated with several viral infections. The aim of this study was to evaluate the progression symptoms, laboratory findings and oseltamivir treatment in children influenza- non-influenza-associated BACM.Patients aged 0-18 years old, admitted pediatric emergency department seasonal influenza period between 2018 2020 were retrospectively analyzed. Patients onset calf tenderness, pain, difficulty walking elevated serum creatine phosphokinase included...

10.1111/ped.15273 article EN Pediatrics International 2022-01-01

This study analyzed the utility of systemic immune-inflammation index (SII) in predicting serious bacterial infections (SBIs) infants with fever without a source (FWS).Infants (aged 1-4 months) evaluated pediatric emergency department for FWS were divided into two groups: SBI and SBI. The efficacy inflammatory markers was compared.The included 223 mean age 76.65 ± 25.42 days; 62 (27.8%) them group, all diagnosed urinary tract infection (UTI). hospitalization rate length hospital stay...

10.1080/00325481.2022.2091373 article EN Postgraduate Medicine 2022-06-16

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral zoonosis with the potential of human-to-human transmission that affects wide areas in Asia, Southeastern Europe, and Africa. Hemorrhagic manifestations constitute prominent symptom late stage disease case fatality rates from 3 to 50%. We present CCHF complicated by pleural effusion resulting resolution without chest tube drainage 9-year-old boy. The diagnosis was confirmed enzyme-linked immunosorbent assay tests. Both serum fluid...

10.7883/yoken.jjid.2009.70 article EN Japanese Journal of Infectious Diseases 2009-01-28

Acute appendicitis is the most common reason for abdominal surgery in children. The aim of this study was to evaluate utility biomarkers predicting complicated (CA).Patients having a diagnosis acute who underwent operations were retrospectively determined, and CA evaluated.A total 251 patients included study. mean age 130.9 ± 48.8 months, 148 cases (59%) simple appendicitis, 103 (41%) CA. C-reactive protein (CRP) levels, immature granulocyte (IG) percentage, white blood cell counts, absolute...

10.1080/00325481.2021.1948306 article EN Postgraduate Medicine 2021-06-24

To evaluate the effectiveness of systemic immune-inflammation index (SII) and other biomarkers in distinguishing parapneumonic effusion (PPE) empyema.Patients who were thought to have pleural secondary pneumonia pediatric emergency department (PED) between 2004 2021 retrospectively evaluated. The patients divided into two groups as empyema PPE. efficacy infection markers predicting was compared.Fifty-nine (59.3% male) included study. Forty-three (72.9%) PPE 16 (27.1%) group. Length hospital...

10.1002/ppul.25926 article EN Pediatric Pulmonology 2022-04-14

Elimination of measles and rubella until the end 2015 in parallel with "World Health Organization (WHO) Europe Region's Measles Elimination" work-up has been targetted "Measles Program'' carried out since 2002 Turkey. Due to routine vaccination programmes number vaccinated children have increased epidemic incidences falling. However, imported cases from other neighboring countries observed Turkey recent two years. Patients who applied Dr. Sami Ulus Maternity Children's Training Research...

10.5578/mb.7024 article EN Mikrobiyoloji Bulteni 2014-04-28

Abstract Introduction Serious bacterial infections (SBI) are major causes of mortality and morbidity in children. The aim this study was to determine the accuracy immature granulocyte (IG) percentage predicting SBI. Methods Patients admitted pediatric emergency department with fever were divided into two groups: SBI non‐SBI. White blood cell (WBC) count, absolute neutrophil count (ANC), C‐reactive protein (CRP), IG value recorded, their evaluated. Results Sixty‐one (14.3%) patients fell...

10.1111/ijlh.13474 article EN International Journal of Laboratory Hematology 2021-02-01

Objective: After the earthquake, which was called ‘Disaster of Century’, affected 11 provinces in our country on February 06, 2023 we presented reflection grievances children who were not trapped under rubble a pediatric emergency clinic 700 km away from region. This study aimed to evaluate ‘earthquake victims’ patients, rubble, applied department (PED) tertiary care children’s hospital. Material and Methods: Between 7 22 2023, data first 15 days after earthquake PED hospital evaluated...

10.12956/tchd.1438227 article EN Turkish Journal of Pediatric Disease 2024-03-25
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