A5068794433- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
- Nosocomial Infections in ICU
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Urinary Tract Infections Management
- Antibiotics Pharmacokinetics and Efficacy
- Escherichia coli research studies
- Bacterial biofilms and quorum sensing
- Infections and bacterial resistance
- Infective Endocarditis Diagnosis and Management
- Viral gastroenteritis research and epidemiology
- Salmonella and Campylobacter epidemiology
- Ocular Infections and Treatments
- Sepsis Diagnosis and Treatment
- Respiratory viral infections research
- Clostridium difficile and Clostridium perfringens research
- Neonatal and Maternal Infections
- Brucella: diagnosis, epidemiology, treatment
- Infectious Diseases and Tuberculosis
- Respiratory Support and Mechanisms
- Ottoman and Turkish Studies
Ege University
2016-2025
Karolinska Institutet
2021
Van Yüzüncü Yıl Üniversitesi
2021
Ege Üniversitesi Tıp Fakültesi Hastanesi
2019-2021
Trakya University
2021
Süleyman Demirel University
2014
Dali University
2014
İstanbul Eğitim ve Araştırma Hastanesi
2014
Hacettepe University
2012
Izmir University
2012
In this study, we aimed to evaluate the epidemiology and antimicrobial resistance (AMR) patterns of bacterial pathogens in COVID-19 patients compare results with control groups from pre-pandemic pandemic era.
To the Editors: Patients receiving interleukin-6 receptor inhibitors, including tocilizumab (TCZ), have been shown to exhibit increased susceptibility infections, mycobacterial and opportunistic pathogens.1 our knowledge, there are limited data regarding severe infections in patients with systemic diseases treated TCZ, except for rheumatoid arthritis some studies on giant cell arteritis.2 Here, we present a case of 6-year-old girl rituximab-refractory autoimmune encephalitis who developed...
Background/Aim: To compare the effectiveness ceftaroline-rifampicin (CR) and vancomycin-rifampicin (VR), against methicillin-resistant Staphylococcus aureus (MRSA) in a rabbit meningitis model, to effects on brain tissues terms of inflammation apoptosis test antibiotics via vitro time-kill synergy tests. Method: Meningitis was induced using MRSA strain ATCC 43300. After 28 hours, rabbits were split into three groups: control, VR, CR. A CSF culture taken at start (T0) end treatment (EOT)-the...
Carbapenems are the choice of treatment in infections caused by multidrug resistant Enterobacteriaceae. In recent years carbapenem-resistant Enterobacteriaceae isolates due to carbapenemases have been increasingly reported worldwide. Multicenter studies on scarce Turkey. The aim this study was determine distribution from different parts Turkey as a part European Survey Carbapenemase Producing (EuSCAPE) project. Beginning November 2013, at least one agents, namely imipenem, meropenem, and...
In this report, we present a case of postneurosurgical meningitis due to Providencia stuartii, which was treated successfully with meropenem therapy lasting 21 days.
Extraintestinal pathogenic Escherichia coli (ExPEC) is an important bacterium and responsible for many bloodstream infections, including urinary tract infections even fatal bacteremia. The aim of this research was to investigate whether ExPEC strains isolated from Turkish blood cultures have a relationship between 16S rRNA based phylogenetic clusters antibiotic resistance profiles, virulence factors or clonal lineages.Phenotypically identified culture isolates (n = 104) were included in...
Background: Linezolid is a bacteriostatic antibiotic with good cerebrospinal fluid penetration. The aim of this study was to evaluate the efficacy linezolid in methicillin-resistant staphylococcal (methicillin-resistant Staphylococcus aureus (MRSA) and coagulase-negative (MRCoNS)) meningitis. Methods: We extracted data outcomes for all adult patients (age > 18 y) culture-proven MRSA or MRCoNS meningitis treated between January 2006 September 2010 our hospital. Demographic, clinical,...
Data are presented from the Survey of Antibiotic Resistance (SOAR) for respiratory tract infection pathogens collected in 2011-13 Turkey.MICs were determined using Etest(®). Susceptibility was assessed CLSI, EUCAST and pharmacokinetic/pharmacodynamic (PK/PD) interpretive criteria.Rates antibiotic susceptibility very low among 333 isolates Streptococcus pneumoniae tested: penicillin 38% CLSI (oral) breakpoints; erythromycin 51% criteria; cefuroxime 64.6% PK/PD 46.9% EUCAST. Of isolates, >90%...
There are several approaches available for purifying microorganisms prior to matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) analysis. In the present study, rapid BACpro® II (Nittobo Medical Co., Ltd., Tokyo, Japan), a new application, has been compared with Sepsityper® kit (Bruker Daltonics, Billerica, USA) and an in-house method. Samples were also tested two modules, standard Sepsityper®, identified in Bruker MALDI-TOF MS. The bottles having...
To evaluate and compare the risk factors, presenting features, outcomes of patients with culture-positive culture-negative microbial keratitis (MK) who presented to a tertiary referral center.We conducted retrospective review medical records 314 were diagnosed MK in our clinic between 2012 2019.Among patients, 142 had positive cultures (45.2%). The mean ages -negative at time diagnosis 51.39±21.31 (range, 14-90) years 56.68±21.34 (7-94) years, respectively (p=0.028). best corrected visual...
Objective To evaluate the serotype distribution and antibiotic resistance in pneumococcal infections adults to provide a perspective regarding coverage of both current future vaccines.Patients methods This passive surveillance study was conducted with Streptococcus pneumoniae strains isolated from specimens patients pneumonia (materials bronchoalveolar lavage), bacteraemia, meningitis, pleuritis peritonitis between 2015 2018. Serogrouping serotyping were performed by latex particle...
AbstractThe increasing prevalence of resistant Gram-positive cocci requires the need to search for more effective agents and synergistic combinations. Forty-two vancomycin- Enterococcus faecium (VREF), 30 methicillin-resistant Staphylococcus aureus (MRSA) 36 epidermidis (MRSE) strains were studied. Minimum inhibitory concentrations (MICs) determined synergy testing was performed by using E test daptomycin, ampicillin-sulbactam, piperacillin-tazobactam ticarcillin-clavulanate against...
Vancomycin is the mainstay of treatment for methicillin-resistant Staphylococcus aureus (MRSA) meningitis. However, successful outcomes with linezolid have not been reported in a large series patients. We conducted single-center retrospective cohort study to compare vancomycin MRSA meningitis.We extracted data and all adult patients (age >18 years) culture-proved meningitis who received or between January 2006 June 2011. A definite diagnosis was based on isolation at least one cerebrospinal...
The aim of this study was to compare the antibacterial activity ceftaroline versus vancomycin in treatment methicillin-resistant Staphylococcus aureus (MRSA) meningitis an experimental rabbit model. compared with induced by MRSA strain ATCC 43300 Quantitative cerebrospinal fluid (CSF) cultures were performed at beginning antibiotic and 24 h 73 after first dose. Furthermore, vitro time–kill data investigated 0, 2, 4, 6, 8, 12 sterile human serum. difference between control group both groups...
Pseudomonas aeruginosa is one of the most virulent bacteria and quorum sensing (QS) genes have an importance on virulence factors such as biofilm that provide resistance against disinfectants antibiotics. This study aimed to determine minimum inhibitory concentrations disinfectants, investigate effects ciprofloxacin production mature clinical P. isolates, it was agents expression levels several QS-related in isolates. Minimum concentration (MIC) polyhexamethylene biguanide (PHMB),...
Comamonas testosteroni , a lesser‐known member of the genus, has shown little apparent capacity for causing infections in humans. We here present case purulent meningitis due to C. which occurred patient who had recurrent cholesteatoma. Ceftriaxone treatment was not effective this even though vitro bacteria were susceptible drug. The responded well meropenem therapy.