A5039443375- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- Hepatitis Viruses Studies and Epidemiology
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Bacterial Infections and Vaccines
- Bacterial biofilms and quorum sensing
- Hepatitis C virus research
- Nosocomial Infections in ICU
- Bacterial Identification and Susceptibility Testing
- Sepsis Diagnosis and Treatment
- Respiratory viral infections research
- Vibrio bacteria research studies
- Antimicrobial Resistance in Staphylococcus
- Liver Disease Diagnosis and Treatment
- Herpesvirus Infections and Treatments
- Neonatal and Maternal Infections
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Urinary Tract Infections Management
- Oral and Craniofacial Lesions
- Microbial infections and disease research
- Infant Nutrition and Health
Cukurova University
2014-2023
Czech Academy of Sciences, Institute of Microbiology
2005
University of Würzburg
2000
Karadeniz Technical University
1998
Istanbul University
1998
Trakya University
1998
Ondokuz Mayıs University
1998
Ankara University
1998
Kocaeli Üniversitesi
1997
We studied the prevalence and molecular epidemiology of PER-1-type beta-lactamases among Acinetobacter, Klebsiella, Pseudomonas aeruginosa strains isolated over a 3-month period in eight university hospitals from distinct regions Turkey. A total 72, 92, 367 P. isolates were studied, respectively. The presence blaPER was determined by colony hybridization method later confirmed isoelectric focusing. detected 46% (33/72) Acinetobacter 11% (40/367) but not Klebsiella strains. enzyme producers...
Background Organizing work flow is a major task of laboratory management. Recently, clinical laboratories have started to adopt methodologies such as Lean Six Sigma and some successful implementations been reported. This study used simplify the process decrease turnaround time by eliminating non‐value‐adding steps. Methods The five‐stage system known define, measure, analyze, improve, control ( DMAIC ) identify solve problems. for individual tests, total delay in sample reception area,...
Background:Nosocomial infections caused by Carbapenem-resistant Klebsiella pneumoniae (CRKP) are increasing. Our aim in this study was to investigate the risk factors of CRKP infections. Material andMethods:A retrospective cohort performed between 1 January and 31 December 2012 ICU patients. Data taken from hospital infection control database for CRKP. The clinical samples collected patients were tested an automatized system disk diffusion. SPSS software v11.5 used statistical analysis....
AbstractAbstractResistance rates to amikacin, ciprofloxacin, ceftazidime, cefepime, imipenem, cefoperazone/sulbactam and piperacillin/tazobactam in Escherichia coli (n= 438)Klebsiella pneumoniae 444)Pseudomonas aeruginosa 210) Acinetobacterbaumanni (n=200) were determined with e-test a multicenter surveillance study (HITIT-2) 2007. ESBL production K. was investigated following the CLSI guidelines. Overall 42.0% of E.coli 41.4% producers. In E. coli, resistance imipenem not observed,...
Objective To evaluate the serotype distribution and antibiotic resistance in pneumococcal infections adults to provide a perspective regarding coverage of both current future vaccines.Patients methods This passive surveillance study was conducted with Streptococcus pneumoniae strains isolated from specimens patients pneumonia (materials bronchoalveolar lavage), bacteraemia, meningitis, pleuritis peritonitis between 2015 2018. Serogrouping serotyping were performed by latex particle...
Tumor necrosis factor-alpha (TNF-alpha) is thought to be an important mediator in the pathogenesis of neonatal septicemia. To assess role TNF-alpha sepsis, serum levels were measured a group neonates with septicemia and compared gestational-postnatal, age-matched healthy controls. The relationships between severity infection, nature causative microorganisms, also investigated this prospective study. A total 49 infants (25 full-term, 24 preterm) proven sepsis 40 (20 20 included. Serum using...
Successful vaccination policies for protection from invasive pneumococcal diseases (IPD) dependent on determination of the exact serotype distribution in each country. We aimed to identify serotypes strains causing IPD children Turkey and emphasize change before after with 7-valent conjugate vaccine (PCV-7) was included PCV-13 newly changed Turkish National Immunization Program. Streptococcus pneumoniae were isolated at 22 different hospitals Turkey, which provide healthcare services...
The aim of this study was to determine the reference ranges lymphocyte subsets in serologically HIV-negative healthy adults Turkey.Blood samples from 220 adults, 105 female and 115 male, collected into tubes containing EDTA were investigated for using flow cytometry. age range 18-80 years (44.80 +/- 16.69).The mean percentage absolute values as follows: CD3: 72.70 8.44%, 1,680 528 cells/microl; CD4: 47.37 9.10%, 1,095 391 CD8: 28.99 5.99%, 669 239 CD19: 10.96 4.44%, 254 122 cells/microl...
Background:Killer cell immunoglobulin-like receptors (KIRs) are a family of inhibitory and activating expressed by natural killer (NK) cells regulate NK activity in the innate response against viral infections. The aim this study was to determine possibility KIR genes genotypes as candidate for susceptibility or protection chronic hepatitis B virus (HBV) infection spontaneous remission Turkish cohort. Material Methods:The present carried out on 37 patients with HBV infection, 36 85 healthy...
Rapid detection of sources and transmission routes by molecular methods provides key data for risk management methicillin-resistant Staphylococcus aureus-induced infections acquired in both the community hospitals. This study aimed to determine clonal relationship S. aureus strains isolated from our hospital pulsed-field gel electrophoresis (PFGE) Staphylococcal protein A (spa) typing identify predominant clones Cukurova Region, Turkey. All isolates analyzed PFGE were distributed among 11...
Objectives: To determine the serotype distribution of pneumococcus causing invasive pneumococcal disease (meningitidis, bacteremia and empyema) in children Turkey, to observe potential changes this time guide effective vaccine strategies.Methods: We surveyed S. pneumoniae with conventional bacteriological techniques real-time polymerase chain reaction (RT-PCR) samples cerebrospinal fluid (CSF), blood pleural fluid. strains were isolated from 33 different hospitals which are giving health...
Objective: Determination of the genotype is critical in process treatment and detection cronic liver diease caused HIV infection.In this study, we examined blood samples patients which have been sent to Central Laboratory Çukurova University Medical Faculty Hospital for HCV genotyping distrubition transmission routes genotypes our region determined by examining file records.Methods: Between January 2015 August 2016, 119 HCV-RNA (COBAS AmpliPrep / COBAS TaqMan real-time PCR, Roche...
AbstractA multicenter antimicrobial surveillance program was established in Turkey 1995 to monitor the predominant Gram-negative pathogens from intensive care units (ICUs) and resistance patterns of these isolates. Sixteen hospitals participated study a total 1479 isolates 1100 patients were collected. The tested for their susceptibility against 13 antibiotics by E-test method. Minimum inhibitory concentrations (MICs) each isolate determined imipenem, ceftazidime, cef-tazidime-clavulanate,...
AbstractAbstractThe study monitored the susceptibility of nosocomial pathogens to meropenem and comparator antimicrobial agents isolated as part Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) Program from Turkish university hospitals. In terms minimum inhibitory concentration 90% (MIC90) values, was two- eight-fold more active than imipenem against Escherichia coli Klebsiella pneumoniae, respectively. 40.5% K. 23.1% oxytoca 15.3% E. isolates were extended-spectrum...
ABSTRACT Before use of the pneumococcal conjugate vaccine PCV7 became widespread in Turkey, 202 invasive pneumococcus isolates were analyzed. The most common serotypes 19F and 6B. In children ≤2 years age, potential coverage rate was 69.5%. frequent non-PCV7 19A, 3, 1, 6A, 8.
Background: Biological variation (BV) data of analytes have been used to evaluate the significant changes in serial results (reference change value, RCV) healthy individuals clinical laboratories.However, BV subjects may not be identical patients with ongoing condition.The aim this study was calculate intra-(CVw) (coefficient for intra-individual BV) and interindividual (CVg) BV, index individuality, RCV nine serum renal posttransplant patients.Methods: Six specimens were obtained an...
Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation. The study aimed to assess serum 14-3-3eta, anti-CarP, and anti-Sa in seronegative RA (SNRA) patients who were treatment-naïve as well healthy subjects. This the first literature examine these autoantibodies together SNRA patients.Forty-five 45 subjects recruited. Drugs change levels of autoantibodies; therefore, took any medication had been excluded from our study. Anti-carbamylated protein, anti-Sa,...