A5050847523- Hepatitis B Virus Studies
- Hepatitis C virus research
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Resistance in Bacteria
- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Antibiotic Use and Resistance
- Diabetic Foot Ulcer Assessment and Management
- Streptococcal Infections and Treatments
- Nosocomial Infections in ICU
- Antibiotics Pharmacokinetics and Efficacy
- Sepsis Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Infectious Diseases and Tuberculosis
- Brucella: diagnosis, epidemiology, treatment
- Urinary Tract Infections Management
- Neutropenia and Cancer Infections
- Antifungal resistance and susceptibility
- Vaccine Coverage and Hesitancy
- Wound Healing and Treatments
- Pneumonia and Respiratory Infections
- Infective Endocarditis Diagnosis and Management
- Antimicrobial Resistance in Staphylococcus
- Pneumocystis jirovecii pneumonia detection and treatment
- Fungal Infections and Studies
Istanbul University-Cerrahpaşa
2016-2025
European Society of Clinical Microbiology and Infectious Diseases
2025
Istanbul University
2014-2024
Sağlık Bilimleri Üniversitesi
2019-2021
Kutahya Saglik Bilimleri Universitesi
2020
Scientific and Technological Research Council of Turkey
2012
Cukurova University
1998-2010
BackgroundBlood stream infections (BSIs) due to carbapenem-resistant Enterobacteriaceae (CRE) are associated with high hospital mortality rates and present a tremendous challenge clinicians. The optimal treatment remains undefined. We aimed investigate the risk factors for correlation between different modalities outcomes.MethodsThe clinical characteristics outcomes of cohort 36 patients BSIs CRE were investigated retrospective nested case–control study surviving non-surviving was...
<h2>Abstract</h2><h3>Objectives</h3> We described the clinical outcomes of diabetic patients who had foot infections with multidrug resistant organisms. <h3>Methods</h3> included (DFI) from 19 centers, between May 2011 and December 2015. Infection was defined according to IDSA DFI guidelines. Patients severe infection, complicated moderate infection were hospitalized. The followed-up for 6 months after discharge. <h3>Results</h3> In total, 791 included, 531(67%) male, median age 62 (19–90)....
Abstract Background The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 non-COVID-19 critically ill patients. Methods We used data from Eurobact II study, a prospective observational multicontinental cohort on HABSI treated in ICU. For current analysis, we selected centers that included both performed descriptive statistics terms patients’ characteristics, source infection microorganism distribution. studied...
ABSTRACT No data on whether brucellar meningitis or meningoencephalitis can be treated with oral antibiotics an intravenous extended-spectrum cephalosporin, namely, ceftriaxone, which does not accumulate in phagocytes, should added to the regimen exist literature. The aim of a study conducted Istanbul, Turkey, was compare efficacy and tolerability ceftriaxone-based antibiotic treatment regimens those protocol patients these conditions. This retrospective enrolled 215 adult 28 health care...
Abstract Background Complicated urinary tract infections (cUTIs) are responsible for a major share of all antibiotic consumption in hospitals. We aim to describe risk factors treatment failure and mortality among patients with cUTIs. Methods A multinational, multicentre retrospective cohort study, conducted 20 countries Europe the Middle East. Data were collected from patients’ files on hospitalised diagnosis cUTI during 2013-2014. Primary outcome was failure, secondary outcomes included 30...
We aimed to investigate the predictors for limb loss among patients with diabetes who have complicated skin/soft-tissue infections. In this observational study, consecutive diabetic foot infection (DFI) from 17 centres in Turkey, between May 2011 and 2013 were included. The Turkish DFI Working Group performed study. Predictors of investigated by multivariate analysis. total, 455 Median age was 61 years, 68% male, 65% hospitalized, 52% had used antibiotics within last month, 121 (27%)...
We aimed to determine significant risk factors for biofilm production and investigate the association between antimicrobial resistance profile formation in bacterial isolates obtained from patients with diabetic foot infection (DFI).Demographic, clinical, laboratory outcome data of 165 patients, prospectively recorded followed January 2008 December 2015 by a multidisciplinary committee, were analysed. Standard microbiological methods adopted. Risk associated determined univariate...
Healthcare workers are among risk groups in the COVID-19. Even if they not infected with disease, witness effects of pandemic. The aim study is to determine factors affecting COVID-19 vaccination status and reasons for vaccine hesitancy healthcare personnel our hospital. Firstly, demographic characteristics all was evaluated. After that, a survey applied 408 vaccinated 297 nonvaccinated personnel. Within first month after beginning vaccination, 66% 3937 received vaccine. number higher...
Both vancomycin (VAN) and teicoplanin (TEI) augment the risk of acute kidney injury (AKI) when combined with piperacillin-tazobactam (TZP). We aimed to compare AKI among patients receiving TZP-VAN versus TZP-TEI. This was a prospective, multinational, multicentre cohort study conducted in 12 centres from Turkiye, Italy Spain between June 1, 2022, December 31, 2023. The primary outcome occurrence first day antibiotic treatment third after completing therapy, according Kidney Disease Improving...
Abstract Background The varicella-zoster virus induces a primary infection known as varicella (chickenpox) and subsequently becomes latent in the dorsal root or cranial nerve ganglia. Later life, may reactivate, leading to secondary called herpes zoster (shingles). Despite increasing population at risk, research on shingles Türkiye is limited. This study aimed assess clinical demographic characteristics of risk factors for postherpetic neuralgia among adults Türkiye.Table 1.Demographic...
Objective We aimed to compare community-onset healthcare-associated (CO-HCA) and hospital-acquired (HA) urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in terms of epidemiology, clinical outcomes antimicrobial activities. Methods Patients from both groups with ESBL-producing E. detected urine culture between January 2009 2011 were included this retrospective study. Relevant demographical, microbiologic data obtained case records....
Background Critically ill COVID-19 patients are prone to bloodstream infections (BSIs). Aim To evaluate the incidence, risk factors, and prognosis of BSIs developing in intensive care unit (ICU). Methods Patients staying at least 48 h ICU from 22 March 2020 25 May 2021 were included. Demographic, clinical, laboratory data analyzed. Results The median age sample (n = 470) was 66 years (IQR 56.0-76.0), 64% male. three most common comorbidities hypertension (49.8%), diabetes mellitus (32.8%),...