Alexis Tabah
A5012692234- Sepsis Diagnosis and Treatment
- Antibiotic Use and Resistance
- Nosocomial Infections in ICU
- Family and Patient Care in Intensive Care Units
- Intensive Care Unit Cognitive Disorders
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial Identification and Susceptibility Testing
- Cardiac, Anesthesia and Surgical Outcomes
- Antibiotic Resistance in Bacteria
- Central Venous Catheters and Hemodialysis
- Emergency and Acute Care Studies
- Respiratory Support and Mechanisms
- Palliative Care and End-of-Life Issues
- Pneumonia and Respiratory Infections
- Renal function and acid-base balance
- Electrolyte and hormonal disorders
- Acute Kidney Injury Research
- Cardiac Arrest and Resuscitation
- Antimicrobial Resistance in Staphylococcus
- Parathyroid Disorders and Treatments
- Antifungal resistance and susceptibility
- Infection Control and Ventilation
- Diabetes and associated disorders
- Climate Change and Health Impacts
- Hemodynamic Monitoring and Therapy
Queensland University of Technology
2021-2025
Redcliffe Hospital
2017-2025
The University of Queensland
2015-2025
Mayne Pharma (Australia)
2024-2025
Royal Brisbane and Women's Hospital
2013-2024
Queensland Centre for Mental Health Research
2024
Research Network (United States)
2023
Services Australia
2023
Prince Charles Hospital
2021
Hôpital Albert Michallon
2009-2013
Corticosteroid therapy induces potentially detrimental hyperglycemia in septic shock. In addition, the benefit of adding fludrocortisone this setting is unclear.To test efficacy intensive insulin patients whose shock was treated with hydrocortisone and to assess, as a secondary objective, fludrocortisone.A multicenter, 2 x factorial, randomized trial, involving 509 adults who presented multiple organ dysfunction, defined by Sequential Organ Failure Assessment score 8 or more, had received...
The Acute Disease Quality Initiative (ADQI) Workgroup recently released a consensus definition of sepsis-associated acute kidney injury (SA-AKI), combining Sepsis-3 and Kidney Improving Global Outcomes (KDIGO) AKI criteria. This study aims to describe the epidemiology SA-AKI.This is retrospective cohort carried out in 12 intensive care units (ICUs) from 2015 2021. We studied incidence, patient characteristics, timing, trajectory, treatment, associated outcomes SA-AKI based on ADQI...
Importance Whether β-lactam antibiotics administered by continuous compared with intermittent infusion reduces the risk of death in patients sepsis is uncertain. Objective To evaluate whether vs a antibiotic (piperacillin-tazobactam or meropenem) results decreased all-cause mortality at 90 days critically ill sepsis. Design, Setting, and Participants An international, open-label, randomized clinical trial conducted 104 intensive care units (ICUs) Australia, Belgium, France, Malaysia, New...
Clinical characteristics, risks, and outcomes in solid organ transplant (SOT) recipients with zygomycosis the era of modern immunosuppressive newer antifungal agent use have not been defined.In a matched case-controlled study, SOT were prospectively studied. The primary outcome measure was success (complete or partial response) at 90 days.Renal failure (odds ratio [OR], 3.17; P = .010), diabetes mellitus (OR, 8.11; < .001), prior voriconazole and/or caspofungin 4.41; .033) associated higher...
Objective: To describe the clinical spectrum of infective endocarditis in critically ill patients and assess impact neurologic complications on outcomes. Design: Prospective multicenter observational study conducted from April 2007 to October 2008. Setting: Thirty-three intensive care units 23 university-affiliated 10 general French hospitals. Patients: Two hundred twenty-five with definite IE were studied. Factors associated predictors 3-month mortality identified by logistic regression...
To examine perceptions by intensive care unit (ICU) workers of unrestricted visitation, to measure visiting times, and determine prevalence symptoms anxiety depression in family members.Observational, prospective, single-center cohort.Medical-surgical ICU a 460-bed tertiary-care hospital.Two hundred nine consecutive patients hospitalized >3 days were studied over the first 5 days.None.Characteristics (n = 209), families 149), 43) collected. reported their members completed Hospital Anxiety...
Rationale: Although intensive care units (ICUs) were created for patients with life-threatening illnesses, the ICU environment generates a high risk of iatrogenic events. Identifying medical errors (MEs) that serve as indicators is crucial purposes reporting and prevention.Objectives: We describe selection indicator MEs, incidence such their relationship mortality.Methods: selected MEs using Delphi techniques. An observational prospective multicenter cohort study these was conducted from...
Our objective was to describe self-sufficiency and quality of life one year after intensive care unit (ICU) discharge patients aged 80 years or over.We performed a prospective observational study in medical-surgical ICU tertiary non-university hospital. We included over at admission 2005 2006 we recorded age, diagnosis, intensity care, severity acute chronic illnesses, as well ICU, hospital, one-year mortality rates. Self-sufficiency (Katz Index Activities Daily Living) assessed discharge....
To determine the number of adult or pediatric intensive care unit patients without documented invasive fungal infection who receive systemic antifungal therapy.A 1-day cross-sectional cohort study.One hundred sixty-nine units in France and Belgium.All staying participating units.None.A hierarchical mixed model was used to identify center-based patient-based determinants therapy use. Day 28 mortality compared with therapy. Two thousand forty-seven were recruited. Systemic 154 (7.5%) patients,...
There is little evidence and few guidelines to inform the most appropriate dosing monitoring for antimicrobials in ICU. We aimed survey current practices around world. An online structured questionnaire was developed sent by e-mail obtain information on local antimicrobial prescribing glycopeptides, piperacillin/tazobactam, carbapenems, aminoglycosides colistin. A total of 402 professionals from 328 hospitals 53 countries responded, whom 78% were specialists intensive care medicine (41%...
The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of empirical treatment is performed in the intensive care unit (ICU) and estimate effect ADE on clinical cure day 7 following initiation. Adult ICU patients receiving therapy for bacterial infection were studied a prospective observational from October 2016 until May 2018. was defined as (1) discontinuation an case combination or (2) replacement with intention narrow spectrum, within first 3 days therapy. Inverse...
Abstract Background The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 non-COVID-19 critically ill patients. Methods We used data from Eurobact II study, a prospective observational multicontinental cohort on HABSI treated in ICU. For current analysis, we selected centers that included both performed descriptive statistics terms patients’ characteristics, source infection microorganism distribution. studied...