A5044713281- Family and Patient Care in Intensive Care Units
- Intensive Care Unit Cognitive Disorders
- Nosocomial Infections in ICU
- Palliative Care and End-of-Life Issues
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Pneumonia and Respiratory Infections
- Emergency and Acute Care Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Grief, Bereavement, and Mental Health
- Healthcare Decision-Making and Restraints
- Frailty in Older Adults
- Central Venous Catheters and Hemodialysis
- Acute Kidney Injury Research
- Antibiotic Resistance in Bacteria
- Medical Malpractice and Liability Issues
- Antibiotic Use and Resistance
- Clinical Nutrition and Gastroenterology
- Patient Safety and Medication Errors
- Geriatric Care and Nursing Homes
- Electrolyte and hormonal disorders
- Vascular Procedures and Complications
- Antibiotics Pharmacokinetics and Efficacy
- Renal function and acid-base balance
Institut Hospitalier Franco Britannique
2017-2025
Hôpital des Diaconesses
2021-2024
Inserm
2012-2023
Université Paris Cité
2014-2023
Hôpital Saint Joseph
2003-2022
Hospital Británico
2022
Délégation Paris 7
2014-2021
Assistance Publique – Hôpitaux de Paris
2003-2021
Infection, Anti-microbiens, Modélisation, Evolution
2015-2021
Hôpital Paris Saint-Joseph
2011-2020
Intensive care unit (ICU) admission of a relative is stressful event that may cause symptoms post-traumatic stress disorder (PTSD).Factors associated with these need to be identified.For patients admitted 21 ICUs between March and November 2003, we studied the family member main potential decision-making role.Ninety days after ICU discharge or death, members completed Impact Event Scale (which evaluates severity reactions), Hospital Anxiety Depression Scale, 36-item Short-Form General Health...
There is a need for close communication with relatives of patients dying in the intensive care unit (ICU). We evaluated format that included proactive end-of-life conference and brochure to see whether it could lessen effects bereavement.
Use of a chlorhexidine gluconate-impregnated sponge (CHGIS) in intravascular catheter dressings may reduce catheter-related infections (CRIs). Changing every 3 days be more frequent than necessary.To assess superiority CHGIS regarding the rate major CRIs (clinical sepsis with or without bloodstream infection) and noninferiority (less 3% colonization-rate increase) 7-day vs 3-day dressing changes.Assessor-blind, 2 x factorial, randomized controlled trial conducted from December 2006 through...
Rationale: Measuring the attributable mortality of ventilator-associated pneumonia (VAP) is challenging and prone to different forms bias. Studies addressing this issue have produced variable controversial results.Objectives: We estimate VAP in a large multicenter cohort using statistical methods from field causal inference.Methods: Patients (n = 4,479) longitudinal prospective (1997–2008) French Outcomerea database were included if they stayed intensive care unit (ICU) for at least 2 days...
Objective: To assess the impact of an intensive care unit diary on psychological well-being patients and relatives 3 12 months after discharge. Design: Prospective single-center study with intervention period between two control periods. Setting: Medical-surgical in a 460-bed tertiary hospital. Patients: Consecutive from May 2008 to November 2009 their relatives. Study inclusion occurred fourth day unit. Interventions: A written by both patient’s staff. Measurements Main Results: Patients...
We evaluated the respective influence of causative pathogen and infection site on hospital mortality from severe sepsis related to community-, hospital-, intensive care unit-acquired infections.We used a prospective observational cohort 10-yr database. built subdistribution hazards model with corrections for competing risks adjustment potential confounders including early appropriate antimicrobial therapy.Twelve units.We included 4,006 first episodes acquisition-site-specific in 3,588...
Rationale: Most vascular catheter-related infections (CRIs) occur extraluminally in patients the intensive care unit (ICU). Chlorhexidine-impregnated and strongly adherent dressings may decrease catheter colonization CRI rates.Objectives: To determine if chlorhexidine-impregnated rates.Methods: In a 2:1:1 assessor-masked randomized trial with catheters inserted for an expected duration of 48 hours or more 12 French ICUs, we compared chlorhexidine dressings, highly adhesive standard from May...
Increasing experimental evidence suggests that acute respiratory distress syndrome (ARDS) may promote AKI. The primary objective of this study was to assess ARDS as a risk factor for AKI in critically ill patients.This an observational on prospective database fed by 18 intensive care units (ICUs). Patients with ICU stays >24 hours were enrolled over 14-year period. defined using the Berlin criteria and Risk, Injury, Failure, Loss kidney function, End-stage disease criteria. before onset...
<h3>Importance</h3> The high mortality rate in critically ill elderly patients has led to questioning of the beneficial effect intensive care unit (ICU) admission and a variable ICU use among this population. <h3>Objective</h3> To determine whether recommendation for systematic reduces 6-month compared with usual practice. <h3>Design, Setting, Participants</h3> Multicenter, cluster-randomized clinical trial 3037 aged 75 years or older, free cancer, preserved functional status (Index...
Colonization of the digestive tract has been supposed to be source many hospital-acquired infections, especially nosocomial pneumonia. To assess relationship between oropharyngeal and gastric colonization subsequent occurrence pneumonia, we prospectively studied 86 ventilated, intensive care unit (ICU) patients. Oropharyngeal or colonizations were detected quantified on admission twice weekly during ICU stay. When pneumonia was suspected clinical grounds (new chest X-ray infiltrate purulent...
Objective To examine the outcome, functional autonomy, and quality of life elderly patients (≥70 yrs old) hospitalized for >30 days in an intensive care unit (ICU). Design Prospective cohort study. Setting A ten-bed, medical-surgical ICU a 460-bed, acute care, tertiary, university hospital. Patients consecutive 75 patients, >70 old, admitted to from January 1, 1993, August 1998, days. Interventions None. Measurements Main Results Severity at admission underlying disease was estimated...
Safety is a global concept that encompasses efficiency, security of care, reactivity caregivers, and satisfaction patients relatives. Patient safety has emerged as major target for healthcare improvement. Quality assurance complex task, in the intensive care unit (ICU) are more likely than other hospitalized to experience medical errors, due complexity their conditions, need urgent interventions, considerable workload fluctuation. Medication errors most common can induce adverse events. Two...
Objective: To identify factors associated with granting or refusing intensive care unit (ICU) admission, to analyze ICU characteristics and triage decisions, describe mortality in admitted refused patients. Design: Observational, prospective, multiple-center study. Setting: Four university hospitals seven primary-care France. Interventions: None. Measurements Main Results: Age, underlying diseases (McCabe score Knaus class), dependency, hospital mortality, were recorded. The crude refusal...
Background. The aim of this study is to describe the prevalence and outcomes intensive care unit (ICU)-acquired hypernatraemia (IAH).