Mickaël Landais
A5014316181- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Nosocomial Infections in ICU
- Clinical Nutrition and Gastroenterology
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Airway Management and Intubation Techniques
- Thermal Regulation in Medicine
- Enhanced Recovery After Surgery
- Anesthesia and Sedative Agents
- Nutrition and Health in Aging
- Traumatic Brain Injury and Neurovascular Disturbances
- Non-Invasive Vital Sign Monitoring
- Inhalation and Respiratory Drug Delivery
- Infectious Encephalopathies and Encephalitis
- Long-Term Effects of COVID-19
- Muscle and Compartmental Disorders
- Leptospirosis research and findings
- Trauma and Emergency Care Studies
- Family and Patient Care in Intensive Care Units
- Bacterial Infections and Vaccines
- Complement system in diseases
- Chemotherapy-related skin toxicity
Centre Hospitalier du Mans
2018-2023
Inserm
2023
Research Network (United States)
2023
French Clinical Research Infrastructure Network
2023
Université de Tours
2023
Université de Bourgogne
2023
Université de Strasbourg
2023
GGG (France)
2008-2014
Centre d'Investigation Clinique de Nantes
2011
Centre Hospitalier Universitaire de Nantes
2011
Moderate therapeutic hypothermia is currently recommended to improve neurologic outcomes in adults with persistent coma after resuscitated out-of-hospital cardiac arrest. However, the effectiveness of moderate patients nonshockable rhythms (asystole or pulseless electrical activity) debated.
Importance The benefit of high-flow nasal cannula oxygen (high-flow oxygen) in terms intubation and mortality patients with respiratory failure due to COVID-19 is controversial. Objective To determine whether the use oxygen, compared standard could reduce rate at day 28 admitted intensive care units (ICUs). Design, Setting, Participants SOHO-COVID randomized clinical trial was conducted 34 ICUs France included 711 a ratio partial pressure arterial fraction inspired equal or below 200 mm Hg....
BackgroundWhether preventive inhaled antibiotics may reduce the incidence of ventilator-associated pneumonia is unclear.MethodsIn this investigator-initiated, multicenter, double-blind, randomized, controlled, superiority trial, we assigned critically ill adults who had been undergoing invasive mechanical ventilation for at least 72 hours to receive amikacin a dose 20 mg per kilogram ideal body weight once daily or placebo 3 days. The primary outcome was first episode during 28 days...
In most patients with nonsevere systemic necrotizing vasculitides (SNVs), remission is achieved glucocorticoids alone, but one-third experience a relapse within 2 years. This study was undertaken to determine whether the addition of azathioprine (AZA) could achieve higher sustained rate newly diagnosed eosinophilic granulomatosis polyangiitis (Churg-Strauss) (EGPA), microscopic (MPA), or polyarteritis nodosa (PAN).All included in this double-blind trial received glucocorticoids, gradually...
Objective: Systemic capillary-leak syndrome is a very rare cause of recurrent hypovolemic shock. Few data are available on its clinical manifestations, laboratory findings, and outcomes those patients requiring ICU admission. This study was undertaken to describe the pictures management severe systemic episodes. Design, Setting, Patients: multicenter retrospective analysis concerned entered in European Clarkson’s disease (EurêClark) Registry admitted ICUs between May 1992 February 2016....
Autoimmune thrombotic thrombocytopenic purpura (TTP) can be associated with other autoimmune disorders, but their prevalence following TTP remains unknown. To assess the of disorders and to determine risk factors for time course development an disorder after a episode, we performed cross sectional study. Two-hundred sixty-one cases were included in French Reference Center registry between October, 2000 May, 2009. Clinical laboratory data available at diagnosis recovered. Each center was...
Background: Although performed daily, intubation in intensive care units (ICU) remains a critical procedure with life-threatening adverse events. High-flow therapy by nasal cannulae (HFNC) is now widespread the operating room and ICU, especially for preoxygenation before non-hypoxemic patients. However, no large randomized study has assessed its relevance this population.
Introduction Pre-emptive inhaled antibiotics may be effective to reduce the occurrence of ventilator-associated pneumonia among critically ill patients. Meta-analysis small sample size trials showed a favourable signal. Inhaled are associated with reduced emergence antibiotic resistant bacteria. The aim this trial is evaluate benefit 3-day course patients undergoing invasive mechanical ventilation for more than 3 days on pneumonia. Methods and analysis Academic, investigator-initiated,...
Few data are available about outcomes of patients screened for, but not enrolled in, randomised clinical trials.We retrospectively reviewed who had non-inclusion criteria for the HYPERION trial comparing 33 °C to 37 in comatose after cardiac arrest non-shockable rhythm, due any cause. A good neurological outcome was defined as a day-90 Cerebral Performance Category score 1 or 2.Of 1144 with criteria, 1130 information and, among these, 158 (14%) functional outcomes, compared 7.9% overall...
PreviousNext No AccessSEG Technical Program Expanded Abstracts 2014Broadband wide-azimuth towed streamer acquisition in West AfricaAuthors: Mickael Landais*Thomas MenschDamien GreniéRichard WombellMickael Landais*CGG, Thomas MenschCGG, Damien GreniéCGG, and Richard WombellCGGhttps://doi.org/10.1190/segam2014-0511.1 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Abstract The Africa Atlantic margin is...
Abstract Background Outcomes of postresuscitation shock after cardiac arrest can be affected by targeted temperature management (TTM). A post hoc analysis the “TTM1 trial” suggested higher mortality with hypothermia at 33 °C. We performed a HYPERION trial data to assess potential associations linking non-shockable °C on favourable functional outcome. Methods divided patients into groups vs. without (defined as need for vasoactive drugs) then assessed proportion outcome (day-90 Cerebral...
Abstract Background Immune suppression has been implicated in the occurrence of pneumonia critically ill patients. We tested hypothesis that Intensive Care Unit (ICU)-acquired is associated with broad host immune aberrations trajectory to pneumonia, encompassing inflammatory, endothelial and coagulation responses. compared plasma protein biomarkers reflecting systemic response patients who acquire a new (cases) those do not (controls). Methods performed nested case–control study undergoing...
Introduction Fasting is frequently imposed to patients before extubation in the intensive care unit based on scheduled surgery guidelines. This practice has never been evaluated among critically ill and may delay extubation, increase nursing workload reduce caloric intake. We are hypothesising that continuous enteral nutrition until represents a safe alternative compared with fasting prior unit. Methods analysis Adult ventilated more than 48 hours receiving pre-pyloric for 24 included this...
Abstract Leptospira propagate via urine shedding by carrier animals with chronic renal infestation, particularly rodents. The growing trend of exotic pet ownership may increase the incidence leptospirosis and lead to a new mode transmission. We report case human whose highly suspected vector was domestic ferret. Careful questioning did not reveal any recent usual context transmission in our patient, only found his pets, which had been contact rodents previous years. Urinary sampling is...