Subhal Dixit
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Clinical Nutrition and Gastroenterology
- Hemodynamic Monitoring and Therapy
- Nutrition and Health in Aging
- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- Airway Management and Intubation Techniques
- Nosocomial Infections in ICU
- Organ Donation and Transplantation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Mosquito-borne diseases and control
- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Acute Kidney Injury Research
- Disaster Response and Management
- Antibiotics Pharmacokinetics and Efficacy
- Trauma and Emergency Care Studies
- Infection Control and Ventilation
- Palliative Care and End-of-Life Issues
- Family and Patient Care in Intensive Care Units
B. J. Medical College & Sassoon Hospital
2017-2025
Lourdes Hospital
2015-2025
All India Institute of Medical Sciences
2024
Medanta The Medicity
2021
Ruby Hall Clinic
2021
Medanta The Medicity
2021
Sher-i-Kashmir Institute of Medical Sciences
2021
Dr. Balabhai Nanavati Hospital
2021
Joshi Hospital
2017
We compared dexamethasone 12 versus 6 mg daily for up to 10 days in patients with coronavirus disease 2019 (COVID-19) and severe hypoxaemia the international, randomised, blinded COVID STEROID 2 trial. In primary, conventional analyses, predefined statistical significance thresholds were not reached. conducted a pre-planned Bayesian analysis facilitate probabilistic interpretation. analysed outcome data within 90 intention-to-treat population (data available 967 982 patients) using models...
A. ACUTE HYPERCAPNIC RESPIRATORY FAILURE A1. Acute Exacerbation of COPD: Recommendations: NIV should be used in management acute exacerbation COPD patients with or acute-on-chronic respiratory acidosis (pH = 7.25-7.35). (1A) attempted <7.25 & PaCO2 ≥ 45) before initiating invasive mechanical ventilation (IMV) except requiring immediate intubation. (2A). Lower the pH higher chance failure NIV. (2B) not to routinely normo- mildly hyper-capneic COPD, without > 7.35). A2. ARF due Chest wall...
The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of empirical treatment is performed in the intensive care unit (ICU) and estimate effect ADE on clinical cure day 7 following initiation. Adult ICU patients receiving therapy for bacterial infection were studied a prospective observational from October 2016 until May 2018. was defined as (1) discontinuation an case combination or (2) replacement with intention narrow spectrum, within first 3 days therapy. Inverse...
Indian Society of Critical Care Medicine (ISCCM) guidelines on Planning and Designing Intensive care (ICU) were first developed in 2001 later updated 2007. These adopted India, many developing Nations major Institutions including NABH. Various international professional bodies critical have their own position papers planning designing ICUs; being the body intensivists India ISCCM therefore addresses subject contemporary context relevant to our clinical practice, its variability according...
India, along with the rest of world, faced challenging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. The second wave in India lagged behind that Western due to different timing seasons. There is scarce data about differences between two waves, for intensive care unit (ICU) patients. We present 3,498 patients from 9 ICUs western Maharashtra.We collected prospective hospitalized, RT-PCR confirmed, coronavirus-2019 (COVID-19) patients, nine tertiary centers, after...
The global pandemic involving severe acute respiratory syndrome-coronavirus-2 (SARS-COV-2) has stretched the limits of science.Ever since it emerged from Wuhan province in China, spread across world and been fatal to about 4% victims.This position statement Indian Society Critical Care Medicine represents collective opinion experts chosen by society.
Background The coronavirus disease 2019 (COVID‐19) pandemic has resulted in millions of deaths and overburdened healthcare systems worldwide. Systemic low‐dose corticosteroids have proven clinical benefit patients with severe COVID‐19. Higher doses are used other inflammatory lung diseases may offer additional benefits At present, the balance between harms higher vs. lower for COVID‐19 is unclear. Methods COVID STEROID 2 trial an investigator‐initiated, international, parallel‐grouped,...
We aimed to study organizational aspects, case mix, and practices in Indian intensive care units (ICUs) from 2018 2019, following the Intensive Care Case Mix Practice Patterns Study (INDICAPS) of 2010-2011.An observational, 4-day point prevalence was performed between 2019. ICU, patient characteristics, interventions were recorded for 24 hours, ICU outcomes till 30 days after day. Adherence selected compliance measures determined. Data analyzed 4,669 adult patients 132 ICUs.On day, mean age,...
Hospital-acquired infections (HAIs) are defined as that develop in the patient after being admitted to hospital. The overall burden of HAIs is known be higher developing countries. most common include ventilator-associated pneumonia (VAP), catheter-associated urinary tract infection (CAUTI), surgical site (SSI), and catheter-related bloodstream (CRBSI). Due limited recent literature, we aimed evaluate incidence rates causative organisms intensive care unit (ICU)-acquired at our tertiary...
Intrahospital transport (IHT) of critically ill patients is essential for diagnostic and therapeutic indications, requiring thorough assessment careful preparation patients, staff, equipment throughout the process. Variability in practices among hospitals can affect patient safety may result adverse events (AEs). This position statement designed to provide guidance multidisciplinary critical care teams adoption evidence-based recommendations aimed at mitigating risks improving during...
PurPose and
Critically ill patients on mechanical ventilation undergo tracheostomy to facilitate weaning. The practice in India may be different from the rest of world and therefore, order understand this, ISCCM conducted a multicentric observational study "DIlatational percutaneous vs Surgical tracheoStomy intEnsive Care uniT: A pattern multicenter (DISSECT Study)" followed by an Expert Panel committee meeting formulate Practice recommendations pertinent Indian ICUs.All existing International...
How to cite this article: Khilnani GC, Tiwari P, Zirpe KG, Chaudhary D, Govil Dixit S, et al. Guidelines for the Use of Procalcitonin Rational Antibiotics. Indian J Crit Care Med 2022;26(S2):S77-S94.
Khilnani GC, Tiwari P, Mittal S, Kulkarni AP, Chaudhry D, Zirpe KG,
How to cite this article: Srinivasan S, Kumar PG, Govil D, Gupta V, Pichamuthu K, et al. Competencies for Point-of-care Ultrasonography in ICU: An ISCCM Expert Panel Practice Recommendation. Indian J Crit Care Med 2022;26(S2):S7-S12.
Short-term central venous catheterization (CVC) is one of the commonly used invasive interventions in ICU and other patient-care areas. Practice management CVC not standardized, varies widely, need appropriate guidance. Purpose this document to provide a comprehensive, evidence-based up-to-date, source for practice catheterization. These recommendations are intended be by critical care physicians allied professionals involved patients with lines.This position statement framed expert...
Coronavirus disease 2019 (COVID-19) can lead to severe hypoxic respiratory failure and death. Corticosteroids decrease mortality in severely or critically ill patients with COVID-19. However, the optimal dose remains unresolved. The ongoing randomised COVID STEROID 2 trial investigates effects of higher vs lower doses dexamethasone (12 6 mg intravenously daily for up 10 days) 1,000 adult COVID-19 hypoxia.
Acute kidney injury (AKI) is a complex syndrome with high incidence and considerable morbidity in critically ill patients. Renal replacement therapy (RRT) remains the mainstay of treatment for AKI. There are at present multiple disparities uniform definition, diagnosis, prevention AKI timing initiation, mode, optimal dose, discontinuation RRT that need to be addressed. The Indian Society Critical Care Medicine (ISCCM) guidelines aim address clinical issues pertaining practices followed RRT,...