Nagarajan Ramakrishnan
A5012150734- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Obstructive Sleep Apnea Research
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Acute Kidney Injury Research
- Sleep and related disorders
- Family and Patient Care in Intensive Care Units
- Neuroscience of respiration and sleep
- Health Systems, Economic Evaluations, Quality of Life
- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- COVID-19 and Mental Health
- Cardiac, Anesthesia and Surgical Outcomes
- Central Venous Catheters and Hemodialysis
- Hemodynamic Monitoring and Therapy
- Palliative Care and End-of-Life Issues
- COVID-19 diagnosis using AI
- Venous Thromboembolism Diagnosis and Management
- Sleep and Wakefulness Research
- Nosocomial Infections in ICU
- Emergency and Acute Care Studies
Apollo Hospitals
2016-2025
META Group
2025
Analysis Group (United States)
2025
Apollo Hospitals
2012-2024
Society of Critical Care Medicine
2022
Ramakrishna Mission Vidyamandira
2022
University of Oxford
2021
CARE Hospitals
2020
Monash University
2020
Alfred Health
2020
Abstract Background We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory emerging Infection Consortium (ISARIC) COVID-19 cohort, one of world's largest international, standardized data sets concerning hospitalized patients. Methods The set analysed includes patients between January 2020 2022 52 countries. investigated how symptoms on admission, co-morbidities, risk factors varied by age, sex other characteristics. used Cox...
Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
To obtain information on organizational aspects, case mix and practices in Indian Intensive Care Units (ICUs).An observational, 4-day point prevalence study was performed between 2010 2011 4209 patients from 124 ICUs. ICU patient characteristics, interventions were recorded for 24 h of the day, outcomes till 30 days after day. Data analyzed 4038 adult 120 ICUs.On mean age, Acute Physiology Chronic Health Evaluation (APACHE II) sequential organ failure assessment (SOFA) scores 54.1 ± 17.1...
Abstract In Coronavirus disease 2019 (COVID-19), early identification of patients with a high risk mortality can significantly improve triage, bed allocation, timely management, and possibly, outcome. The study objective is to develop validate individualized scores based on the anonymized clinical laboratory data at admission determine probability Deaths 7 28 days. Data 1393 admitted (Expired—8.54%) was collected from six Apollo Hospital centers (from April July 2020) using standardized...
The efficacy of vitamin C for hospitalized patients with COVID-19 is uncertain.
To assess the attitudes of practitioners with respect to net ultrafiltration prescription and practice among critically ill patients acute kidney injury treated renal replacement therapy.
<h2>Summary</h2><h3>Background & aims</h3> Guidance on managing the nutritional requirements of critically ill patients in intensive care unit (ICU) has been issued by several international bodies. While these guidelines are consulted ICUs across Asia–Pacific and Middle East regions, there is little guidance available that tailored to unique healthcare environments demographics regions. Furthermore, lack consistent data from randomized controlled clinical trials, reliance expert consensus,...
Abstract ISARIC (International Severe Acute Respiratory and emerging Infections Consortium) partnerships outbreak preparedness initiatives enabled the rapid launch of standardised clinical data collection on COVID-19 in Jan 2020. Extensive global participation has resulted a large, comprehensive from hundreds sites across dozens countries. Data are analysed regularly reported publicly to inform patient care public health response. This report, our 18th final is part series published over 3...
To assess the feasibility, tolerance and effectiveness of enteral nutrition in critically ill patients receiving invasive mechanical ventilation prone position for severe Acute Respiratory Distress Syndrome (ARDS).Prospective observational study conducted a multidisciplinary critical care unit tertiary hospital from January 2013 until July 2015. All with ARDS who received during period were included. Patients' demographics, severity illness (Acute Physiology Chronic Health Evaluation (APACHE...
Use of sedation, analgesia and neuromuscular blocking agents is widely practiced in Intensive Care Units (ICUs). Our aim to study the current practice patterns related mobilization, analgesia, relaxants sedation (MARS) help standardizing best practices these areas ICU.A web-based nationwide survey involving physicians Indian Society Critical Medicine (ISCCM) Anesthesiologists (ISA) was carried out. A questionnaire included questions on demographics, assessment scales for delirium, pain, as...
The Randomized Embedded Multifactorial Adaptive Platform (REMAP-CAP) adapted for COVID-19) trial is a global adaptive platform of hospitalised patients with COVID-19. We describe implementation in three countries under the umbrella Wellcome supported Low and Middle Income Country (LMIC) critical care network: Collaboration Research, Implementation Training Asia (CCA). collaboration sought to overcome known barriers multi centre-clinical trials resource-limited settings. Methods described...
We aimed to study organizational aspects, case mix, and practices in Indian intensive care units (ICUs) from 2018 2019, following the Intensive Care Case Mix Practice Patterns Study (INDICAPS) of 2010-2011.An observational, 4-day point prevalence was performed between 2019. ICU, patient characteristics, interventions were recorded for 24 hours, ICU outcomes till 30 days after day. Adherence selected compliance measures determined. Data analyzed 4,669 adult patients 132 ICUs.On day, mean age,...
We aimed to study decision-making preferences and levels of anxiety depression in family members patients admitted the intensive care unit (ICU). This was a prospective observational done mixed medical-surgical ICU. About 127 were recruited first analysis 100 second analysis. Decision-making obtained only during Hospital scale (HADS) scores calculated both times. more than or equal 11 found have depression. also association between Around 27 relatives did not give consent time 61% preferred...
Background and Aims: Tidal volume (TV) challenge was shown to improve the reliability of pulse pressure variation (PPV) in predicting responsiveness. Carotid peak velocity (CPV) has similar potential predict This study compared performance CPV PPV responsiveness following a TV challenge. Methodology: In patients with haemodynamic instability, baseline were measured at 6 ml/kg (CPV6 PPV6) 8 (CPV8 PPV8), changes (∆CPV (6–8) ∆PPV (6–8)) recorded. The then reduced ml/kg. After fluid bolus (6...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbon-13 nuclear magnetic resonance spectroscopy of naturally occurring substances. 54. Structure analysis the nucleoside disaccharide antibiotic anthelmycin by carbon-13 spectroscopy. A structural revision hikizimycin and its identity with anthelmycinMarc Vuilhorgne, Sofiane Ennifar, Bhupesh C. Das, Jonathan W. Paschal, Ramakrishnan Nagarajan, Edward Hagaman, Ernest WenkertCite this: J. Org. Chem. 1977, 42, 20, 3289–3291Publication Date...
parameter properly or the needs further development in form of precision and complexity 'vital few' problems have not been identified.A constant engagement with improvement process is necessary on part team.The to be developed, validated revalidated same unit different units among similar dissimilar case mix before it finally accepted.
Obstructive sleep apnea (OSA) and obstructive syndrome (OSAS) are subsets of sleep-disordered breathing. Awareness about OSA its consequences among the general public as well majority primary care physicians across India is poor. This necessitated development Indian initiative on (INOSA) guidelines under auspices Department Health Research, Ministry Family Welfare, Government India. occurrence an average five or more episodes respiratory events per hour with either sleep-related symptoms...
<ns4:p><ns4:bold>Background: </ns4:bold>The epidemiology of critical illness in India is distinct from high-income countries. However, limited data exist on resource availability, staffing patterns, case-mix and outcomes illness. Critical care registries, by enabling a continual evaluation service provision, epidemiology, availability quality, can bridge these gaps information. In January 2019, we established the Indian Registry IntenSive to map capacity describe outcomes. this report,...