- Hepatitis C virus research
- Hepatitis B Virus Studies
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Hepatitis Viruses Studies and Epidemiology
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Liver Disease Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Bacterial biofilms and quorum sensing
- Mycobacterium research and diagnosis
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- HIV-related health complications and treatments
- Herpesvirus Infections and Treatments
- Leptospirosis research and findings
- Urinary Tract Infections Management
- Reproductive tract infections research
- Pharmaceutical and Antibiotic Environmental Impacts
- Antifungal resistance and susceptibility
- Bacterial Infections and Vaccines
- Parasitic Infections and Diagnostics
- Hydrogen's biological and therapeutic effects
- Infectious Diseases and Mycology
- Vibrio bacteria research studies
Ondokuz Mayıs University
2004-2019
Giresun University
2019
Gümüşhane University
2018
Istanbul University
2014-2017
Istanbul University-Cerrahpaşa
2014-2017
Ahi Evran University
2016
Istanbul 29 Mayis University
2013
Adli Tıp Kurumu
2013
Inonu University
2011
Czech Academy of Sciences, Institute of Microbiology
1998
The objective of this study was to determine the contamination rate healthcare workers' (HCWs') mobile phones and hands in operating room ICU. Microorganisms from HCWs' could be transferred surfaces during their use.200 HCWs were screened; samples 200 participants cultured.In total, 94.5% demonstrated evidence bacterial with different types bacteria. gram negative strains isolated 31.3% ceftazidime resistant 39.5%. S. aureus 52% those 37.7% methicillin resistant. Distributions microorganisms...
This study was carried out with the participation of eight hospitals in Turkey to determine frequency gram-negative bacteria isolated intensive care units (ICU) and compare their resistance rates selected antibiotics. Aerobic from ICUs during 1996 were studied. Antibiotic susceptibilities imipenem, ceftazidime, ceftazidime-clavulanate, ceftriaxone, cefotaxime, cefepime, cefodizime, cefuroxime, piperacillin/tazobactam, amoxycillin-clavulanate, gentamicin, amikacin ciprofloxacin determined by...
Carbapenems are the choice of treatment in infections caused by multidrug resistant Enterobacteriaceae. In recent years carbapenem-resistant Enterobacteriaceae isolates due to carbapenemases have been increasingly reported worldwide. Multicenter studies on scarce Turkey. The aim this study was determine distribution from different parts Turkey as a part European Survey Carbapenemase Producing (EuSCAPE) project. Beginning November 2013, at least one agents, namely imipenem, meropenem, and...
With the participation of eight major reference hospitals in Turkey, 749 aerobic Gram-negative isolates obtained from 473 intensive care patients 1997 were tested for their susceptibility to 13 commonly employed antibacterial agents. The frequency with which species isolated and resistance rates compared data previous 2 years. Imipenem was most active agent against majority (75%), followed by ciprofloxacin, cefepime amikacin. per cent all antibiotics declined 1995 1996. exception imipenem,...
Data are presented from the Survey of Antibiotic Resistance (SOAR) for respiratory tract infection pathogens collected in 2011-13 Turkey.MICs were determined using Etest(®). Susceptibility was assessed CLSI, EUCAST and pharmacokinetic/pharmacodynamic (PK/PD) interpretive criteria.Rates antibiotic susceptibility very low among 333 isolates Streptococcus pneumoniae tested: penicillin 38% CLSI (oral) breakpoints; erythromycin 51% criteria; cefuroxime 64.6% PK/PD 46.9% EUCAST. Of isolates, >90%...
Aims: To investigate plasmid-mediated quinolone resistance in clinical isolates of Pseudomonas aeruginosa with the polymerase chain reaction (PCR). The genes have been identified many bacteria within Enterobactericeae family, they not detected P. isolates. Subjects and Methods: Identification testing antibiotic susceptibility was performed Vitek2 Compact (Biomeriux, France) Phoinex (BD, USA) automated systems. Screening for qnrA, qnrB, qnrS, qnrC, aac (6′)-Ib-cr qepA carried out by PCR...
AbstractAbstractThe aim of this study was to evaluate the antibiotic prescription rates for upper respiratory tract infections (uRTIs) by primary care physicians in Samsun, Turkey. Data were obtained from records 2083 visits 8 areas. Trained research students stationed on site at each areas during period. Clinical features patients documented a standardized form. Patients who had acute pharyngitis, sinusitis, otitis media (AOM) and common cold included study. This survey conducted between...
Mycobacteria other than tuberculosis (MOTT) cause increasingly serious infections especially in immunosuppressive patients by direct transmission from the environment or after colonization. However, identification of these species is difficult because cost and difficulties defining to level. Identification distribution can help clinician choice treatment. A total 90 MOTT strains obtained four different centers were included study. These identified sequence analysis 16S rRNA Hsp65 genetic...
The epidemiological distribution and clinical features of 12 cases Weil's disease from Turkey, are reviewed. is most common in male farmers rural areas. Myalgia jaundice were recorded all patients. Signs included vomiting 9 patients, haemorrhages 6, renal function was impaired 6. Creatine phosphokinase levels found above normal limits 75% the cases. Leptospires demonstrated with dark-field microscopy blood urine 5 these diagnosis confirmed microscopic agglutination test (MAT) as well ELISA....
Super-oxidized water is one of the broad spectrum disinfectants, which was introduced recently. There are many researches to find reliable chemicals effective, inexpensive, easy obtain and use, effective for disinfection microorganisms leading hospital infections. Antimicrobial activity super-oxidized promising. The aim this study investigate in-vitro antimicrobial different concentrations Medilox® that approved by Food Drug Administration (FDA) as high level disinfectant. In study, obtained...
AbstractA multicenter antimicrobial surveillance program was established in Turkey 1995 to monitor the predominant Gram-negative pathogens from intensive care units (ICUs) and resistance patterns of these isolates. Sixteen hospitals participated study a total 1479 isolates 1100 patients were collected. The tested for their susceptibility against 13 antibiotics by E-test method. Minimum inhibitory concentrations (MICs) each isolate determined imipenem, ceftazidime, cef-tazidime-clavulanate,...
ABSTRACT Before use of the pneumococcal conjugate vaccine PCV7 became widespread in Turkey, 202 invasive pneumococcus isolates were analyzed. The most common serotypes 19F and 6B. In children ≤2 years age, potential coverage rate was 69.5%. frequent non-PCV7 19A, 3, 1, 6A, 8.
<i>Background/Aims:</i> This study was designed to investigate the dose-dependent protective effect of ivabradine, a specific inhibitor cardiac sinoatrial node, on renal ischemia-reperfusion (I/R) injury in rats. <i>Methods:</i> Rats were divided into six groups: group 1, control; 2, I/R (60 min ischemia followed by 24 h reperfusion); groups 3 and 4, 0.6–6 mg/kg ivabradine; 5 6, sham+0.6–6 ivabradine. At end study, malondialdehyde (MDA), superoxide dismutase (SOD),...
In critically ill patients, mild to moderate reductions in glomerular filtration rate are not instantly followed by parallel changes serum creatinine (SCr). The aim of this study was identify a value cystatin C (cys-C) level as marker for monitoring renal function pediatric patients. Creatinine clearance used estimate glomeruler (eGFR). correlation between the inverse cys-C and eGFR (r = −0.70, p < 0.0001) better than SCr −0.27, 0.008). Serum found be superior predict impairment (area under...
Mycobacterium tuberculosis is still a major health problem throughout the world, especially in developing countries. Disease control heavily depends on establishment of early diagnosis. The aim this study to compare efficacy culture, GeneXpert MTB/RIF device, and Erlich-Ziehl-Neelsen direct microscopic method.A total 927 samples (243 respiratory 684 nonrespiratory), which were sent Ondokuz Mayıs University Medical Faculty Tuberculosis Laboratory suspicion M. tuberculosis, included study.When...
Mycobacterium tuberculosis is still a substantial health problem universally. Although culture the gold standard method, reliable, rapid and new methods are required for effective struggle with disease. We retrospectively compared results of Ehrlich-Ziehl-Neelsen (EZN) stain real-time DNA amplification assay (BD ProbeTec ET system) culture.Retrospective study.A total 703 samples, 182 pulmonary 521 extra pulmonary, collected from 630 patients between May 2008 February 2011 were evaluated....
Objective:The aim of this study was to investigate the distribution and antibiotic susceptibility Acinetobacter species isolated in our hospital last six years.Method: from various
Stenotrophomonas maltophilia is an opportunistic emergent pathogen causing hospital-acquired infections. It resistant to majority of the broad spectrum antibiotics due several mechanisms which significantly limit treatment options. Although relationship between integrons, mobile genetic elements play role in transferring resistance genes, and antibiotic different gram-negative bacteria have been investigated, data are limited Turkey especially for S.maltophilia. The aims this study were...
Abstract Objective Although the regulatory effects of substance‐P (SP), neurokinin‐A (NKA), calcitonin gene‐linked peptide (CGRP) and neuropeptide‐Y (NPY) on periodontal inflammatory responses have been described, these neuropeptides healthy diseased periimplant tissues are not clearly defined. Materials methods Thirty‐nine implants loaded at least for 12 months with their symmetrically matching teeth were evaluated compared by a split‐mouth study design. Six groups created in this regard as...