- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Antibiotics Pharmacokinetics and Efficacy
- Mycobacterium research and diagnosis
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Tuberculosis Research and Epidemiology
- Antibiotic Use and Resistance
- Infections and bacterial resistance
- Pharmaceutical and Antibiotic Environmental Impacts
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Enterobacteriaceae and Cronobacter Research
- Antifungal resistance and susceptibility
- SARS-CoV-2 detection and testing
- Infectious Diseases and Tuberculosis
- Probiotics and Fermented Foods
- Microbial infections and disease research
- Fungal Infections and Studies
- Hepatitis Viruses Studies and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Salmonella and Campylobacter epidemiology
- Bacterial Infections and Vaccines
- Urinary Tract Infections Management
Ondokuz Mayıs University
2016-2025
Weatherford College
2024
UCSI University
2023
Samsun University
2023
Textile Institute of Pakistan
2021
Istanbul 29 Mayis University
2020
Memorial Ankara Hospital
2014-2015
Ankara Mevki Asker Hastanesi
2013
Lower respiratory tract infections are an important cause of morbidity and mortality. Identification infectious etiology is very for specific treatment. In addition to routine methods in diagnosis, polymerase chain reaction-based tests have been used. By identifying pathogenic organisms antibiotic resistance markers earlier than methods, these the potential accurately detect agent reduce duration therapy. The aim this study show that use multiplex method may be useful early diagnosis study,...
<title>Abstract</title> <bold>Introduction</bold> In this study, we analyzed the clinical features of nosocomial meningitis caused by <italic>Acinetobacter baumannii</italic> (<italic>A. baumannii</italic>) to identify factors affecting outcome and compared effectiveness different therapeutic regimens. <bold>Methods</bold> The study patients diagnosed with healthcare-associated due A. baumannii, cases between 2017 2022 were included. <bold>Results</bold> We data from 52 patients. 14-day...
The aim of this study was to investigate the effects acute anaerobic exercise on serum levels adipokines Zinc-α2-glycoprotein (ZAG), apelin, and lipasin. Eighteen male athletes who actively played soccer trained at least four days a week, with mean age 19.11 ± 2.59 years, body weight 70.61 8.17 kg, height 176.0 7.71 cm, sport 7.22 2.60 years BMI 22.76 1.68 kg/m2 participated in study. Athletes were subjected Running-Based Anaerobic Sprint Test (RAST) for performance. Blood samples collected...
Aims: To investigate plasmid-mediated quinolone resistance in clinical isolates of Pseudomonas aeruginosa with the polymerase chain reaction (PCR). The genes have been identified many bacteria within Enterobactericeae family, they not detected P. isolates. Subjects and Methods: Identification testing antibiotic susceptibility was performed Vitek2 Compact (Biomeriux, France) Phoinex (BD, USA) automated systems. Screening for qnrA, qnrB, qnrS, qnrC, aac (6′)-Ib-cr qepA carried out by PCR...
Background: Pseudomonas aeruginosa is an important opportunistic pathogen, and carbapenem resistance emerging problem. The determination of genes vital for epidemiological purposes, the early carbapenemase production methods also recommended. Objectives: present study aimed to investigate presence VIM, NDM, IMP, GES, SPM, GIM, SIM in P. isolates. Methods: In this study, 200 carbapenem-resistant isolates were included. DNA extraction was performed using boiling method. Following extraction,...
Treatment of drug-resistant Mycobacterium tuberculosis infections requires combination anti-tuberculosis drugs which have several toxic side effects. Thus there is a need for safer and effective new drugs. Ankaferd Blood Stopper® (ABS), mixture plant extracts prepared from Alpinia officinarum, Glycyrrhiza glabra, Thymus vulgaris, Urtica dioica Vitis vinifera, has homeostatic antibacterial Standard solutions ABS are already being used topically post-traumatic post-operative bleeding control...
There is a need for laboratory marker that correlates with the clinical activity of Behçet's disease (BD).We aimed to investigate whether serum galectin-3 (Gal-3) levels were affected during course regard activity.A total 131 subjects involved in study as follows: Group 1: BD active (n = 39); 2: inactive 31); 3: Disease controls leucocytoclastic vasculitis confirmed skin biopsy 22); and 4: Healthy control 39). The patients followed regularly samples taken their periods over 2-year...
Mycobacterium tuberculosis (MTB) is one of the most significant causes mortality and morbidity. Early diagnose important especially in multiple drug resistant to avoid transmission. Traditional techniques requires at least three weeks for diagnosis tuberculosis. Diagnostic delays with are associated worse clinical outcomes increased transmission The Xpert MTB/RIF assay new diagnostic device rapid detection rifampicin resistance.We assessed performance detecting resistance using phenotypic...
Aspergillus spp. are widespread in nature and cause severe infections especially immunocompromised patients. fumigatus complex is the most common species that causes humans; however niger flavus emerging agents isolated frequently from clinical specimens more recently. Besides host factors such as immunosuppression, hematologic malignancy corticosteroid use, fungal virulence elastase, acid protease phospholipase enzymes considered among affect development of invasive aspergillosis. The aim...
In this study we evaluated the crystal violet decolorization assay (CVDA) for detection of minimum inhibitory concentration (MIC) antituberculosis drugs. 53 isolates were tested in and 13 them multidrug resistant (MDR) isolates. The antibiotics concentrations 2-0.06 mg/L isoniazid (INH) rifampicin (RIF) 16-0.25 streptomycin (STM) ethambutol (EMB). Crystal (CV-25 mg/L) was added into microwells on seventh day incubation continued until decolorization. Decolorization CV predictor bacterial...
Carbapenem resistance is an emerging problem in Enterobactarales. We aimed to investigate the presence of carbapenemase genes blaNDM, blaKPC, blaVIM and blaOXA-48 evaluate phenotypic blue-carba method carbapenem inactivation (CIM) Enterobacterales isolates.Total 153 isolates were tested study. Presence was investigated by polymerase chain reaction (PCR) method. Carbapenemase production also CIM.The gene detected 110 (71.4%) blaNDM 2 (1.3%) PCR None positive for blaKPC genes. The 121 (78.54%)...
Antimicrobial resistance (AMR) is one of the most important problems threatening human health worldwide. The impact Coronavirus disease-2019 (COVID-19) pandemic on AMR continues to be discussed. Some researchers argue that will increase rates, while others suggest opposite. aim this study was investigate change in Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus strains three cross-sectional periods Türkiye, first before COVID-19 pandemic, second third during pandemic....
Enterococcus faecalis is the bacterium most commonly isolated from infected root canals. This study evaluated effects of four instrumentation techniques on reducing E. in curved Sixty maxillary first molar teeth were used. After mesiobuccal canals had been instrumented with nickel–titanium (NiTi) K-files up to size 25, autoclaved, immersed a broth inoculated faecalis, and incubated for 48 hours. The divided into experimental groups (n = 15). mesial using ProTaper, RaCe, Mtwo rotary...
Background: The quick diagnosis and early initiation of antibiotic therapy in bacteria-induced infections is paramount importance. Accordingly, the rapid identification causative agent, short-term results sensitivity, selection use right antibiotics for treatment further highlights significance this issue. Objectives: This study aimed to develop a new susceptibility testing method provide Escherichia coli clinical isolates report test clinicians short period. Methods: In study, one hundred...