- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Dialysis and Renal Disease Management
- Nosocomial Infections in ICU
- Hemodynamic Monitoring and Therapy
- Body Composition Measurement Techniques
- Inflammatory Biomarkers in Disease Prognosis
- Cardiovascular Health and Disease Prevention
- Renal Diseases and Glomerulopathies
- Inflammasome and immune disorders
- Cardiovascular Function and Risk Factors
- Psoriasis: Treatment and Pathogenesis
- Cardiovascular Disease and Adiposity
- Respiratory Support and Mechanisms
- Systemic Sclerosis and Related Diseases
- Renal function and acid-base balance
- Pulmonary Hypertension Research and Treatments
- Chronic Kidney Disease and Diabetes
- Platelet Disorders and Treatments
- Peptidase Inhibition and Analysis
- HIV-related health complications and treatments
- Autoimmune and Inflammatory Disorders Research
- Cardiovascular Syncope and Autonomic Disorders
- Galectins and Cancer Biology
- Infection Control in Healthcare
Dicle University
2015-2025
Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi
2021
Namık Kemal University
2019-2020
Sağlık Bilimleri Üniversitesi
2019
Eskişehir Osmangazi University
2018
Izmir Tepecik Eğitim ve Araştırma Hastanesi
2018
Recep Tayyip Erdoğan University
2015
Ondokuz Mayıs University
2011-2012
Istanbul 29 Mayis University
2012
Samsun University
2011
Fluid overload is a common and serious problem that leads to severe complications in dialysis patients. We aimed compare hydration status as measured with bioimpedance analysis (BIA) method hemodialysis (HD) peritoneal (PD) patients, well investigating the association between blood pressure, left ventricular mass index (LVMI) status. examined 43 HD 33 PD Blood pressure was recorded. In each group, echocardiographic examinations were performed on all Hydration assessed using multifrequency...
BACKGROUND:Pulmonary arterial hypertension (PAH) is common disease among hemodialysis (HD) patients and associated with increased morbidity mortality. However, its pathogenesis has not been completely elucidated. We aimed to evaluate the frequency of PAH in HD patients, as well relationship between fluid status PAH. MATERIAL AND METHODS:We enrolled 77 this study. Multifrequency bioimpedance analysis (BIA) was used assess status. BIA performed before 30 min after midweek HD. Overhydration...
Background: Determination of fluid overload is important in chronic kidney disease. Early diagnosis and treatment volume may decrease morbidity mortality. We aimed to determine body composition by using bioelectrical impedance analysis, studying other clinical characteristics, inferior vena cava diameter, N-terminal pro-B natriuretic peptide associated with hydration status disease Stages 3&4 5 patients not undergoing dialysis. Method: examined 62 68 Stage Plasma NT-proBNP was measured...
Sleep disorders have recently become a significant public health problem worldwide and deleterious consequences. Obstructive sleep apnea (OSA) is the most common type of sleep-related breathing disorders. We aimed to evaluate anthropometric measurements, glucose metabolism, cortisol levels in patients with obstructive (OSA).A total 50 body mass index ≥30 major OSA symptoms were included this study. Anthropometric measurements recorded blood samples drawn for laboratory analysis. A 24-hour...
Maintenance of fluid status within an optimal range and accurate assessment dry weight (DW) is essential in patients on intermittent haemodialysis (HD) treatment. In this study, we aimed to investigate the association measured by bioimpedance analysis (BIA) with N-terminal pro-B natriuretic peptide (NT-proBNP), blood pressure left ventricular mass index (LVMI) hemodialysis patients.A total 45 were enrolled study. (NT-proBNP) was immunoassay. Blood (BP) recorded. Echocardiographic...
<i>Background:</i> Lichen sclerosus (LS), is characterized by localized patches of atrophy and whitening the skin. The cause LS remains unknown, but genetic, hormonal, immunologic factors autoimmune mechanisms have been incriminated. There are conflicting data regarding association between human leukocyte antigens (HLA). <i>Methods:</i> We analyzed HLA alleles a family, in which 4 5 children lichen sclerosus. <i>Results:</i> HLA-B*08 HLA-B*18 were detected...
There is a need for laboratory marker that correlates with the clinical activity of Behçet's disease (BD).We aimed to investigate whether serum galectin-3 (Gal-3) levels were affected during course regard activity.A total 131 subjects involved in study as follows: Group 1: BD active (n = 39); 2: inactive 31); 3: Disease controls leucocytoclastic vasculitis confirmed skin biopsy 22); and 4: Healthy control 39). The patients followed regularly samples taken their periods over 2-year...
The pathophysiology of coronary slow flow (CSF) has not been clarified. Salusin-β is released predominantly from the atheroma plaques and influences pathophysiologic processes atherosclerosis. Therefore, this study aimed to determine serum salusin-β levels in CSF its correlation with CSF.The included 39 patients CSF, control group (n=42) consisted consecutive subjects normal arteriogram. We measured thrombolysis myocardial infarction frame count (TFC).Age, body mass index (BMI), systolic...
INTRODUCTION: Sepsis is an important cause of mortality and morbidity, inflammatory response oxidative stress play major roles underlying its pathophysiology. Here, we evaluated the effect intraperitoneal etanercept administration on inflammation indicators in kidney blood experimental sepsis-induced rats. METHODS: Twenty-eight adult Sprague Dawley rats were classified into Control (Group 1), 2), Sepsis+Cefazolin 3), Sepsis+Cefazolin+Etanercept 4) groups. Kidney tissue serum samples obtained...
To evaluate the relationship between disease activity and levels of alpha 1-acid glycoprotein pentraxin 3 in patients with Behçet's (BD).Forty-eight BD 29 age- gender-matched healthy control subjects were included study. Serum measured using enzyme-linked immunosorbent assay (ng/ml), nephelometry (mg/dl). Disease was assessed Current Activity Form (BDCAF).Serum alpha-1 acid significantly higher compared to group (P = 0.048). There no significant differences two groups terms 0.697). According...
Data on health problems and fatal complications associated with coronavirus disease (COVID-19) have consistently been reported. Although immune thrombocytopenia has multiple viral infections, only few studies shown its association COVID-19. Here, we reported a case series of two cases pertaining to patients diagnosed COVID-19-associated thrombocytopenia, elaborating the clinical course, management, response treatment.
To investigate the effectiveness of controlled reperfusion (CR) on ovarian tissue malondialdehyde, total glutathione and 8-hydroxyguanine levels infertility rates in a rat model induced ischemia-reperfusion (I/R) injury with unilateral oophorectomy.A 135 adult female albino Wistar rats were divided into 9 groups (n = 15 for each group): ovariectomy + I/R (OIR), alone (OEG), sham operation group (SG), CR performed at different intervals (the clips released 10 times 10, 8, 6, 4, 2 or 1 s...
Introduction and aim Acute kidney injury (AKI) is part of the multiple organ dysfunction syndrome in critically ill patients a common condition intensive care units (ICUs). Renal replacement therapy (RRT) cornerstone treatment for AKI patients. This patient population has high mortality rate despite RRT. There are two methods RRT ICUs: intermittent hemodialysis (IHD) continuous renal (CRRT). Both CRRT IHD similarly provide adequate metabolic control. We aimed to compare these modalities...
BACKGROUND The main cause of mortality among chronic kidney disease (CKD) patients is cardiovascular (CVD). Epicardial adipose tissue (EAT) considered to be novel risk factor. We assessed EAT in non-dialyzed stage 5 CKD and explored the association with body composition as determined by multi-frequency BIA. MATERIAL AND METHODS present included 70 who had not undergone dialysis 40 healthy control subjects. thickness was echocardiography. Hydration status were evaluated bioelectrical...
Monocyte to high-density lipoprotein (HDL) cholesterol ratio (MHR) has emerged as a novel marker of endothelial injury, inflammation, and oxidative stress. This study aimed investigate the effect MHR on primary nephrotic syndrome (NS) its relationship with severity proteinuria. enrolled 161 patients newly diagnosed NS 100 healthy individuals. Demographic characteristics patients, diagnosis, basal laboratory parameters, amount 24-hour urinary protein excretion, were recorded. The groups...
Aim: Acute kidney injury (AKI) is a clinical syndrome that can cause disturbances in fluid-electrolyte and acid-base balance, resulting the accumulation of nitrogen uremic toxins along with loss functions within hours or days. In this study, it was aimed to retrospectively examine patients acute determine whether there relationship between infection parameters urine volume. Materials Methods: The study included total 144 (n=74) without (n=70) out 294 AKI who received treatment 1 January 2020...
Amaç: Bu çalışmada, rutin hemodiyalize giren HBsAg negatif hasta serum örneklerinde HBV DNA incelemesi ile okült prevalansı ve HCV prevalansının saptanması hedeflendi. Aynı zamanda non-invaziv bir metot olan fibrometer karaciğer fibrozis düzeyi belirlenmesi amaçlandı. Yöntemler: Çalışmaya hemodiyaliz amacıyla başvuran tarama testlerinde 100 dahil edildi. Hastadan alınan örneklerde, ALT, HBsAg, Anti-HBc IgG, DNA, Anti HCV, RNA aynı örneklerinden çalışıldı. pozitif hastalar Hepatit B olarak...
Objective: It is known that the need for invasive mechanical ventilation due to severe respiratory failure develops in COVID-19 patients followed intensive care unit. has been reported literature coagulopathy seen during disease an important cause of mortality and morbidity. Our aim our study was evaluate coagulation disorders developing between intubated non-intubated patients. Method: The data 812 diagnosed with Intensive Care Unit, March 2020 September 2021 were retrospectively analyzed....
<title>Abstract</title> <bold>Purpose: </bold>Chronic kidney disease (CKD) is a global public health issue, often associated with high mortality and morbidity, especially due to cardiovascular diseases. Epicardial adipose tissue (EAT), the visceral fat surrounding heart, has been recognized as significant factor in risk. This study aims assess relationship between EAT thickness body composition patients stage 4 5 CKD usingbioelectrical impedance analysis (BIA). <bold>Methods: </bold>The...
Amaç: Böbrek biyopsisi, böbrek parankimal hastalıkların histopatolojik tanısının konulmasında sıklıkla kullanılan altın standart bir yöntemdir. biyopsi kayıtları ile hastalıklarının epidemiyolojisi belirlenir. Literatürdeki çalışmalar incelendiğinde proteinüri en sık endikasyonu olarak karşımıza çıkmaktadır. Glomerulonefritler ise (GN) görülen sonuçlar olmaktadır. GN alt tiplerinin dağılımı coğrafi bölge, yaş, etnik kökene göre değişebilmektedir. Bizde bu çalışmada bölgemizdeki sonuçlarına...
Objective: Acute kidney injury (AKI) is an important clinical entity that known to increase mortality in patients with sepsis. Erythrocyte maturation and proliferation are inhibited by pro-inflammatory cytokines; these cytokines exert effects on red cell distribution width (RDW) well. Based this knowledge; our aim study was evaluate the impact of RDW acute Methods: 120 diagnosed sepsis admitted intesive care unit (ICU) treated between 2009-2013 were retrospectively evaluated. Patients...
Introduction: Hospital-acquired infections (HAI) occurring in intensive care units (ICUs) are an important risk factor for mortality and morbidity. In some patient groups followed ICUs, the of developing nosocomial increases even more. Especially, patients with end-stage renal disease (ESRD) carry a serious HAI when they hospitalized ICUs. Our aim is to determine rate incidence hospital infection, distribution most common microorganisms our ICU, initiate appropriate empirical treatment...