A5066171147- Bacterial Identification and Susceptibility Testing
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- Urinary Tract Infections Management
- Bacterial Infections and Vaccines
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Clostridium difficile and Clostridium perfringens research
- Mycobacterium research and diagnosis
- Respiratory viral infections research
- Respiratory and Cough-Related Research
- Antibiotic Use and Resistance
- Pediatric Urology and Nephrology Studies
- Diphtheria, Corynebacterium, and Tetanus
- Tuberculosis Research and Epidemiology
- Bacterial biofilms and quorum sensing
- Viral gastroenteritis research and epidemiology
- Urinary Bladder and Prostate Research
- Immunodeficiency and Autoimmune Disorders
- Neonatal and Maternal Infections
- Neonatal skin health care
- Cystic Fibrosis Research Advances
- Antifungal resistance and susceptibility
- Antibiotics Pharmacokinetics and Efficacy
- Radiopharmaceutical Chemistry and Applications
Marmara University
2012-2025
TÜBİTAK Marmara Research Center
2024
ENT and Allergy
2023
Türkisch-Deutsche Universität
2019
Objective: This study aimed to compare the performance of carbapenem inactivation method (CIM) and modified hodge test (MHT) screen carbapenemase activity in Klebsiella pneumoniae isolates with genotypically confirmed results. Materials Methods: A total 114 carbapenem-resistant K. clinical were collected from hospitalized patients. Two methods, MHT CIM, used investigate production. The CIM was evaluated at 6th hour for preliminary decision 24th final decision. hour. polymerase chain reaction...
The increasing prevalence of Gram-negative bloodstream infections in pediatric patients poses significant treatment challenges, particularly from multi-drug resistant (MDR) strains. Despite advances medical care, mortality remains a concern. Our study aims to understand patients` demographics, clinical conditions, and microorganisms causing infections, as well identify factors affecting outcomes mortality. A retrospective, observational bacteremia, including all < 18 years age, hospitalized...
HIV-1 genotyping and drug resistance tests are routinely performed in virology laboratories some countries, aiding clinical management. In Istanbul, between January 2021 March 2024, plasma samples from 1029 HIV-1-infected patients were analyzed using the NGS method, mutation results retrospectively evaluated alongside demographic data. Subtype B (54.4%) was most frequent Turkish patients, while A1 (43.5%) predominant among foreign nationals. The common CRFs CRF02_AG (3.8%) CRF56_cpx (1.6%)....
The aim of this study was to determine the association between Clostridium difficile (C. difficile) and vancomycin-resistant Enterococcus (VRE) efficacy screening stools submitted for C. toxin assay prevalence VRE. Between April 2012 February 2014, 158 stool samples Marmara University Microbiology Laboratory, were included in study. Stool analyzed by enzyme immuno test; VIDAS (bioMerieux, France) Toxin A&B. Samples inoculated on chromID VRE incubated 24h at 37°C. Manuel tests API20 STREP...
To investigate the effect of intravesical hyaluronic acid on Escherichia coli-induced cystitis and cystitis-induced hypercontractility in rats.Bacterial was induced Wistar female rats by inoculation E. coli. Isotonic saline instilled control group (n = 6). The were either non-treated, treated with gentamycin (4 mg/kg, 5 days) or intravesically (0.5 mL, 0.5%). On eighth day, bladder tissues excised for histological examination, measurements myeloperoxidase, superoxide dismutase catalase...
Antimicrobial resistance (AMR) is one of the most important problems threatening human health worldwide. The impact Coronavirus disease-2019 (COVID-19) pandemic on AMR continues to be discussed. Some researchers argue that will increase rates, while others suggest opposite. aim this study was investigate change in Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus strains three cross-sectional periods Türkiye, first before COVID-19 pandemic, second third during pandemic....
Abstract Background : An absence of Haemophilus influenzae type b (Hib) disease surveillance and epidemiological data on the pharyngeal carriage Turkish children causes delay in introduction conjugated Hib vaccination into proposed national programs. Methods Oropharyngeal cultures were obtained from 1404 healthy infants children. Six child clinic (HCC), 11 day‐care centers (DCC) seven elementary schools (ES) randomly selected different counties at Anatolian side Istanbul between January...
Background/aim: Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry is an alternative way of identifying mycobacteria via the analysis biomolecules. It being increasingly used in routine microbiology practice since it permits early, rapid, and cost-effective identification pathogens clinical importance. In this study, we aimed to evaluate efficacy phenotypic by MALDI-TOF MS MBT Mycobacteria Library (ML) 4.0 (Bruker, Daltonics) compared standard sequence...
Abstract Urinary tract infections are one of the most common bacterial and rapid diagnosis infection is essential for appropriate antibiotic therapy. The goal our study was to identify urinary pathogens directly by MALDI-TOF MS perform susceptibility tests in order shorten period spent culturing. Urine samples submitted culture Clinical Microbiology Laboratory were enrolled this study. screened leukocyte bacteria amount flow cytometry. Samples with load 10 6 –10 7 /mL tested (AST) performed....
Sepsis, defined as an increase of 2 points or more in the sequential organ failure assessment score, is a life-threatening dysfunction caused by dysregulated host response to infection. Volume-conductivity-scatter (VCS) parameters cell counters which are known population data (CPD) have been suggested be beneficial diagnosing sepsis. We aimed evaluate diagnostic value CPD sepsis comparison nonsystemic infection cases (NSI) and non-infectious acute chronic inflammatory conditions.We...