A5060612868- COVID-19 Clinical Research Studies
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Nosocomial Infections in ICU
- Fluid Dynamics and Turbulent Flows
- Intensive Care Unit Cognitive Disorders
- Wind and Air Flow Studies
- SARS-CoV-2 and COVID-19 Research
- Renal function and acid-base balance
- Cardiac Arrest and Resuscitation
- Long-Term Effects of COVID-19
- Antibiotic Use and Resistance
- Extracellular vesicles in disease
- Combustion and flame dynamics
- Electrolyte and hormonal disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Aerodynamics and Acoustics in Jet Flows
- Cardiac and Coronary Surgery Techniques
- Aerodynamics and Fluid Dynamics Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Mesenchymal stem cell research
- Abdominal Surgery and Complications
- Family and Patient Care in Intensive Care Units
- Emergency and Acute Care Studies
Marmara University
2016-2025
Heinrich Heine University Düsseldorf
2007-2023
Istanbul University
2022
Marmara Üniversitesi Eğitim ve Araştırma Hastanesi
2016-2021
Ankara Atatürk Eğitim ve Araştırma Hastanesi
2018
Afyon Kocatepe University
2018
Karadeniz Technical University
2018
Adıyaman University
2018
Amerikan Hastanesi
2018
Sakarya University
2018
This study was conducted methodologically to evaluate the Turkish validity and reliability of Feeling Safe During Surgery Scale assess its suitability for population. methodological collected data from 148 patients who underwent elective surgery with regional anesthesia in general clinics a university hospital Istanbul between December 1, 2021 June 30, 2022. Data were obtained through face-to-face interviews using Patient Information Form, developed by researchers based on literature,...
Aim: New coronavirus disease (COVID-19) has become an international emergency. As many of the intensive care unit (ICU) patients with also present multiple organ failure, blood purification techniques might be a good choice in their treatment. In this study we aimed to investigate role cytokine removal COVID-19 managed ICUs. Methods: For case-control have investigated by means two resin membranes (HA330 and Mediasorb) Particularly, overtime variation clinical severity scores, laboratory...
The scale of the COVID-19 pandemic forced urgent measures for development new therapeutics. One these strategies is use convalescent plasma (CP) as a conventional source passive immunity. Recently, there has been interest in CP-derived exosomes. In this report, we present structural, biochemical, and biological characterization our proprietary product, human immune plasma-derived exosome (ChipEXO), following guidelines set forth by Turkish Ministry Health Red Crescent, Good Manufacturing...
This is a single-center prospective, open-label, single arm interventional study to test the safety and efficacy of recently described ChipEXO™ for severe COVID-19 pneumonia. The natural product derived from convalescent human immune plasma patients recovered moderate infection. In September 2021, 13 with pending respiratory failure were treated adapted aerosolized formulation delivered via jet nebulizer. Patients received 1-5x1010 nano vesicle/5 mL in distilled water twice daily five days...
Background Coronaviruses have been the cause of 3 major outbreaks during last 2 decades. Information on coronavirus diseases in pregnant women is limited, and even less known about seriously ill women. Data are also lacking regarding real burden disease 2019 (COVID-19) infection from low/middle-income countries. The aim this study was to determine characteristics clinical course COVID-19 pregnant/puerperal admitted ICUs Turkey. Methods This a national, multicenter, retrospective study....
Abstract Background We report a nosocomial outbreak caused by Burkholderia cepacia that occurred among six patients admitted in the medical and surgical intensive care unit between 04 March 2019 02 April Istanbul, Turkey. Methods The investigation was launched on 11 five days after detection of B. four different patients. defined potential reservoirs started environmental screening. sampled liquid solutions used patient activities. Pulse-field gel electrophoresis (PFGE) performed to...
Vaccines against coronavirus disease-19 (COVID-19) have been effective in preventing symptomatic diseases, hospitalizations, and intensive care unit (ICU) admissions. However, data regarding the effectiveness of COVID-19 vaccines reducing mortality among critically ill patients with remains unclear.To determine vaccination status investigate impact vaccine on 28-day COVID-19.Multicenter prospective observational clinical study.This study was conducted 60 hospitals ICUs managing COVID-19....
Neurologic complications during on-pump cardiovascular surgery are often induced by mobilization of atherosclerotic plaques, which is directly related to enhanced wall shear stress. In the present study, we numerically evaluated impact dispersive aortic cannulas on blood flow characteristics, with special regard resulting stress profiles. An idealized numerical model human aorta and its branches was created used straight as well bent meshlike tips inserted in distal ascending aorta. Standard...
Management of Crush-related Acute Kidney Injury After DisastersRecently, on February 6, 2023, a 7.8 magnitude earthquake struck southeastern Turkey and neighboring states.It has become the worst disaster ever recorded in region, with over 40,000 deaths, rescue operations have not been finalized yet.This incident should stress importance preparedness, foresight, organization our management system for during natural or artificial disasters.The experiences these mournful days are hard-learned...
Healthcare-associated infection is an important cause of mortality and morbidity worldwide. Well-regulated control hand hygiene are the most effective methods for preventing healthcare-associated infections. This study evaluated compared conventional observation electronic hand-hygiene recording reminder system infections.This pre- post-intervention study, employed infections at a tertiary referral center. surveillance was recorded in anesthesia reanimation intensive care unit from April...
Abstract Candida bloodstream infections are associated with high mortality among critically ill patients in intensive care units (ICUs). Studies that explore the risk factors for candidemia may support better patient units. We conducted a retrospective, multicenter case-control study to investigate noncatheter-related (CBSI) adult ICUs. Participants selected controls randomly on 1:1 basis all noncase stayed during same period Data 139 cases and 140 were deemed eligible. Among controls, 69...
BACKGROUND: Intra-abdominal hypertension (IAH) is a frequent cause of acute kidney injury (AKI) among critically ill patients who have risk factors.This study aimed to determine the relation between Abdominal Perfusion Pressure (APP) and AKI showed by Doppler-based renal resistive index (RRI). METHODS:In this study, 38 older than 18 years old received mechanical ventilation had factors for development IAH were prospectively studied.All measurements parameters divided into two groups...
Sepsis, defined as an increase of 2 points or more in the sequential organ failure assessment score, is a life-threatening dysfunction caused by dysregulated host response to infection. Volume-conductivity-scatter (VCS) parameters cell counters which are known population data (CPD) have been suggested be beneficial diagnosing sepsis. We aimed evaluate diagnostic value CPD sepsis comparison nonsystemic infection cases (NSI) and non-infectious acute chronic inflammatory conditions.We...
Agmatine (CAS 2482-00-0), an amine formed by decarboxylation of L-arginine, interacts with several targets like α<sub>2</sub>-adrenergic, imidazoline and N-methyl-D-aspartic acid (NMDA) receptors besides it is involved in the nitric oxide mediated effects. It has also been proposed that possesses vasodilator effects increases glomerular filtration rate rats. The aim this study was to supply evidence for agmatine a rat model hemorrhagic shock explain possible mechanisms action. iliac arteries...
Abstract An industrial biomass boiler of 200 kW thermal power is analyzed by computational and experimental methods. Gas composition temperature within the furnace in downstream heat exchanger are measured. Combustion, flow transfer processes furnace, exhaust tract as well forced convection on water side computationally investigated finite volume method‐based fluid dynamics procedures. The predictions compared with experiments. A satisfactory overall agreement between predicted measured...
Flow in a polyurethane model of human aorta, driven by heart-lung machine, is analyzed experimentally and computationally for antegrade retrograde perfusion. The purpose the analysis validation previously proposed loss-coefficient-based outlet boundary condition aortic branches. This claimed to be commonly applicable different perfusion modes unlike alternative straightforward constant-pressure condition. First, experimentally. step delivers loss-coefficients that are used any other mode...
We aimed to obtain information about the characteristics of ICUs in our country via a point prevalence study.
ABSTRACT Background Coronavirus disease 2019 (COVID-19) quickly spread worldwide to become a pandemic. This study aimed define the predictors of critical illness development within 28 days postadmission. Methods We conducted prospective cohort including 477 PCR-positive COVID-19 patients admitted tertiary care hospital in Istanbul from March 12 May 12, 2020. The illness, e.g., invasive mechanical ventilation and/or death, was followed for period Demographic characteristics, number...