A5033547827- Extracellular vesicles in disease
- RNA Interference and Gene Delivery
- Tissue Engineering and Regenerative Medicine
- Biomedical Ethics and Regulation
- Sphingolipid Metabolism and Signaling
- SARS-CoV-2 and COVID-19 Research
- MicroRNA in disease regulation
- COVID-19 Clinical Research Studies
- Pluripotent Stem Cells Research
- Retinoids in leukemia and cellular processes
Yeditepe University
2022-2024
Abstract Extracellular vesicles are secreted by all eukaryotic cells and they have an important role in intercellular signaling. Plant extracellular (PEVs) a novel area of research that has gained attention due to their potential implications biomolecule transport therapeutic applications. PEVs lipid bilayer‐enclosed structures contain diverse cargo biomolecules such as proteins lipids. Moreover, it is known noticeable for various conditions inflammation oxidative stress. However, there...
The scale of the COVID-19 pandemic forced urgent measures for development new therapeutics. One these strategies is use convalescent plasma (CP) as a conventional source passive immunity. Recently, there has been interest in CP-derived exosomes. In this report, we present structural, biochemical, and biological characterization our proprietary product, human immune plasma-derived exosome (ChipEXO), following guidelines set forth by Turkish Ministry Health Red Crescent, Good Manufacturing...
Melanoma arises from the uncontrolled multiplication of melanocytes, and poses an escalating global health concern. Despite importance early detection surgical removal for effective treatment, metastatic melanoma treatment challenges, with limited options. Among optional therapies, including chemotherapy immunotherapy, all-trans retinoic acid (ATRA), a natural metabolite vitamin A, has shown promise in treating by inducing differentiation, apoptosis, growth arrest, immune modulation cells....