- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Macrophage Migration Inhibitory Factor
- Respiratory Support and Mechanisms
- COVID-19 diagnosis using AI
- Nutrition and Health in Aging
- Pneumonia and Respiratory Infections
- Intensive Care Unit Cognitive Disorders
- Cardiac Arrest and Resuscitation
- Organ Donation and Transplantation
- Long-Term Effects of COVID-19
- Inflammasome and immune disorders
- Emergency and Acute Care Studies
- SARS-CoV-2 and COVID-19 Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Family and Patient Care in Intensive Care Units
- Organ Transplantation Techniques and Outcomes
- Refrigeration and Air Conditioning Technologies
- Nosocomial Infections in ICU
- Neurological and metabolic disorders
- Gender Studies and Social Issues
- Skin Diseases and Diabetes
- Abdominal Surgery and Complications
- Historical Turkish Studies
Dokuz Eylül University
2013-2022
Izmir University
2019-2022
Faculty (United Kingdom)
2022
Antalya IVF
2021
Türk Anesteziyoloji ve Reanimasyon Derneği
2019
Ege University
2017
Abstract Objective To assess whether there is a statistically significant difference in the frequency of common MEFV allele variants patients with ankylosing spondylitis (AS) as compared control rheumatoid arthritis (RA) and healthy subjects. Methods Sixty‐two AS, 50 subjects, 46 RA were assessed for presence variants. Exon 10 was analyzed by direct sequencing. E148Q restriction endonuclease enzyme digestion (REED) or sequencing when REED analysis failed. Results The all AS group...
Background/aim: Coronavirus disease 2019 (COVID-19) is a with high rate of progression to critical illness. However, the predictors mortality in critically ill patients admitted intensive care unit (ICU) are not yet well understood. In this study, we aimed investigate risk factors associated ICU our hospital. Materials and methods: single-centered retrospective enrolled 86 adult COVID-19 Dokuz Eylül University Hospital (İzmir, Turkey) between 18 March 2020 31 October 2020. Data on...
Introduction. We sought to identify possible risk factors associated with mortality in patients high-risk pulmonary embolism (PE) after intensive care unit (ICU) admission. Patients and Methods. PE patients, diagnosed computer tomography angiography, were included from two ICUs categorized into groups: group 1 2 intermediate/low-risk patients. Results. Fifty-six included. Of them, 41 (73.2%) 15 (26.7%) 2. When compared 2, need for vasopressor therapy (0 vs 68.3%; p < 0.001) invasive...
Objective: In reports, abnormal macrophage migration-inhibitory factor (MIF) production has been associated with several diseases. Furthermore, despite scarce data, increasing evidence suggest that MIF plays a central role in glucose homeostasis and the development of type 1 2 diabetes. However, serum levels gestational diabetes mellitus (GDM) have not yet investigated. To address this question, we performed prospective study between group pregnant women GDM healthy controls. Materials...
Objective . Oxygen therapy is one of the most common treatment modalities for hypoxemic patients, but target goals normoxemia are not clearly defined. Therefore, iatrogenic hyperoxia a very situation. The results from recent clinical researches about indicate that can be related to worse outcomes than expected in some critically ill patients. According our literature knowledge, there any reports researching effect on course patients who treated with invasive mechanical ventilation. In this...
To determine the level of macrophage migration inhibitory factor (MIF), its relationship with Mediterranean fever (MEFV) gene mutations and oxidative stress in familial (FMF).Fifty one unrelated attack free FMF patients (24 M 27 F, 32.8±8.7 years) 30 healthy controls (16 14 32.7±7 were included study. Serum MIF, total oxidant status (TOS) anti-oxidant (TAS) studied.Age, sex distribution, anthropometrical indices, smoking status, serum lipids TAS concentrations similar between controls....
Penetrating gunshot head injuries have a poor prognosis and require prompt care. Brain CT is routine component of the standard evaluation wounds suspected brain injury. We aimed to investigate effect findings on mortality in injury patients who were admitted our emergency department (ED) from Syrian Civil War.The study group comprised ED with Patients' GCS scores, prehospital intubations examined.104 included (92% male, mean age 25 years). Pneumocephalus, midline shift, penetrating injury,...
Levothyroxine intoxication is a rare clinical entity which usually asymptomatic. However, severe symptoms such as respiratory failure, malignant hyperthermia, seizures, arrhythmia, and coma have been reported. In this case report, patient who ingested high dose (15 mg) levothyroxine for suicide admitted to intensive care unit was presented. There decrease in Glasgow score the follow-up. The intubated due acute failure. Gastric lavage, activated charcoal, methylprednisolone, cholestyramine...
Scleromyxedema is an uncommon connective tissue disease characterized by mucin deposits, fibrosis, and proliferation of fibroblasts in the dermis. Although it shares similar sclerodermoid features, a different clinical entity than scleroderma. A monoclonal gammopathy almost always present; however, progression to multiple myeloma rare. It may have many systemic manifestations, which most notable being dermato-neuro syndrome because its rarity potential fatal outcome. We present case...
Objective: Emotional and physical burden is heavy in the intensive care unit (ICU) employees, risk of burnout has significantly increased.The purpose this study to determine frequency depression nurses serving tertiary ICUs a university hospital by questionnaire. Material Methods:The questionnaire was conducted on studying actively Dokuz Eylül University School Medicine Anesthesia Internal ICU between 22-26 August 2016.Burnout assessed Maslach Burnout Scale (MBS) with Beck Depression...
We aimed to obtain information about the characteristics of ICUs in our country via a point prevalence study.
Diabetic ketoacidosis (DKA) is an acute and major life-threatening complication of diabetes mellitus. Fluid resuscitation, insulin therapy, electrolyte replacement are essential for DKA treatment. Rarely, life threatening allergic reactions might develop in a patient treated with insulin. If anaphylaxis develops after insulin, the treatment options restricted. A limited number case reports have been reported patients severe anaphylactic to human who were then synthetic analogues. We present...
Pneumocephalus is a complication of trauma to the chest and many iatrogenic interventions. It may arise due systemic air embolism or retrograde cerebral venous which an extremely rare complication. We report 26-years-old female patient who presented Emergency Department suffering multiple stab wounds. She was in state shock after first aid evaluation she operated successfully. In early postoperative period generalized tonic clonic convulsions were observed following cardiopulmonary...
Objective: Although many new interventions including changes in diagnostic policies are performed to increase the rates of diagnosis brain death (BD) and organ donation recent years Turkey, data about longitudinal effects limited.The aim this study was understand current status İzmir find out whether regulations have any effect on BD rates.Materials Methods: All patients diagnosed with between January 2001 December 2016 a tertiary university hospital were included, patient collected from...
In patients with coronavirus disease 2019, the gastrointestinal symptoms have been reported increasingly in addition to respiratory system symptoms. The studies show that prevalence of and how contributes severity prognosis is still not clear. This study aims find correlation between clinical results hospitalized diagnosed 2019.This retrospectively analyzes 2019 pandemic unit March 2020 August compares their demographic characteristics, laboratory radiologic findings, treatments received,...
Background: The aim of this study is to evaluate the prognostic factors at medical ICU admittance predicting intensive care unit (ICU) mortality in cancer patients.Methods: Retrospectively data adult patients admitted a 1200-bed university hospital during January 2012-December 2013 interval were analysed. divided into three groups; with solid tumor, hematologic malignancy and without cancer. end point was mortality.Results: 512 identified; 374 cancer, 89 tumor 49 malignancy. Overall rate 46%...
ÖZET Halen tartışmalı olması ve literatürde sık rastlanmaması nedeniyle noninvaziv mekanik ventilasyon ile başarılı bir şekilde tedavi ettiğimiz Akut respiratuvar distress sendromu (ARDS) olgumuz ilgili tecrübelerimizi paylaşmak istiyoruz.Yirmi altı yaşındaki Burkitt lenfoma tanılı erkek hasta kemoterapi sonrası nötropenik ateş sepsis ilişkili ARDS tanılarıyla yoğun bakıma yatırıldı.Hastanın bilincinin kooperasyonunun iyi sebebiyle PO 2 /FiO =114,2 olmasına rağmen başlandı.Noninvaziv destek...
<h3>Background</h3> Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent, inflammatory, self-limited episodes of and serositis. Neutrophils are one the key players in pathophysiology FMF. Macrophage migration inhibitory factor (MIF) a pleiotropic cytokine involved several inflammatory processes including innate adaptive immune responses. In addition, MIF has been shown to regulate trafficking cells neutrophils sites inflammation. Because its...