- Thyroid Disorders and Treatments
- Diabetes and associated disorders
- Thyroid Cancer Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Nuclear Structure and Function
- Hormonal Regulation and Hypertension
- COVID-19 Clinical Research Studies
- Diabetes Treatment and Management
- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Pituitary Gland Disorders and Treatments
- Adrenal Hormones and Disorders
- Blood Coagulation and Thrombosis Mechanisms
- Diabetes Management and Research
- Sexual Differentiation and Disorders
- Vitamin D Research Studies
- Metabolism, Diabetes, and Cancer
- Cancer, Hypoxia, and Metabolism
- Liver Disease Diagnosis and Treatment
- Gestational Diabetes Research and Management
- Inflammasome and immune disorders
- Bone health and treatments
- RNA Research and Splicing
- Growth Hormone and Insulin-like Growth Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
Dokuz Eylül University
2015-2024
Izmir Bozyaka Eğitim ve Araştırma Hastanesi
2021
Education Training And Research
2021
Izmir Kâtip Çelebi University
2021
Istanbul University
2006-2017
Ege University
2017
Bursa Uludağ Üni̇versi̇tesi̇
2017
Dr. Behçet Uz Çocuk Hastalıkları Hastanesi
2017
Eskişehir Osmangazi University
2010-2013
Afyon Kocatepe University
2008-2011
This study assessed the effects of glucagon-like peptide-1 (GLP-1)/glucagon receptor co-agonist efinopegdutide relative to selective GLP-1 agonist semaglutide on liver fat content (LFC) in patients with non-alcoholic fatty disease (NAFLD).This was a phase IIa, randomized, active-comparator-controlled, parallel-group, open-label study. A magnetic resonance imaging-estimated proton density fraction assessment performed determine LFC at screening and Week 24. Participants an ≥10% were...
Aim: We wished to investigate the relationship between metabolic syndrome and erectile dysfunction (ED). Materials methods: A total of 268 patients were included in this study. All asked fill an International Index for Erectile Function (IIEF) questionnaire. The presence was determined when any three or more five risk factors present according National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP)‐III. factor ED status logistic regression analysis. Results: Eighty‐nine...
Context: Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near-total lack of body fat. Objective: We aimed to study natural history and disease burden various subtypes CGL. Design: attempted ascertain nearly all patients with CGL in Turkey. Setting: This was nationwide study. Patients or Other Participants: Participants included 33 (22 families) 30 healthy controls. Main Outcome Measure(s): wanted genotypes sequencing the known genes....
We determine the prevalence of premature ejaculation in patients with hyperthyroidism and observed intravaginal latency time alterations before after treatment.Between January 2004 June 2007, 49 no history treatment were enrolled study. After obtaining a detailed sexual anamnesis an erectile function questionnaire was completed patient self-reported outcome measure difficult control over examined. assessed stopwatch measurements performed by or partner. Patient anxiety status also evaluated....
Coronavirus disease 2019 (COVID-19) has been reported to be associated with a more severe course in patients type 2 diabetes mellitus (T2DM). However, adverse outcomes are not recorded all patients. In this study, we assessed and without T2DM hospitalized for COVID-19.A nationwide retrospective cohort of confirmed COVID-19 infection from 11 March 30 May 2020 the Turkish Ministry Health database was investigated. Multivariate modeling used assess independent predictors demographic clinical...
Abstract Context The aims of the study are to compare characteristics subacute thyroiditis (SAT) related different etiologies, and identify predictors recurrence SAT incident hypothyroidism. Methods This nationwide, multicenter, retrospective cohort included 53 endocrinology centers in Turkey. participants were divided into either COVID-19–related (Cov-SAT), SARS-CoV-2 vaccine–related (Vac-SAT), or control (Cont-SAT) groups. Results Of 811 patients, 258 (31.8%) Vac-SAT group, 98 (12.1%)...
Abstract Background Lipodystrophy is a rare disease characterized by loss of adipose tissue. Natural history studies have demonstrated significant burden disease; however, there limited data on the impact lipodystrophy quality life (QoL) and psychoemotional well-being. The QuaLip study prospective observational real-world that aims to determine QoL well-being explore subjective disease. Sixty-seven adult patients eight pediatric with were included. Patients followed up for 24 months...
We aimed to evaluate the predictors of subsequent development postpartum carbohydrate intolerance, metabolic syndrome and cardiovascular risk factors in women with previous GDM. Two hundred fifty-two consecutive GDM were enrolled. After exclusion who did not attend hospital for follow-up visits minimum 1 year, data 195 patients evaluated. Seventy-one lean negative screening included as a control group. The prevalence diabetes, impaired glucose tolerance fasting was significantly higher than...
AimsTo confirm non-inferiority of insulin degludec/insulin aspart (IDegAsp) once-daily (OD) versus glargine (IGlar) U100 OD + (IAsp) for HbA1c after 26 weeks, and compare efficacy safety between groups at W26 W38.MethodsA 38-week, randomised, open-label, treat-to-target (HbA1c < 7.0%) trial in adults with type 2 diabetes mellitus (on basal ± oral antidiabetic drugs; 7.0–10.0%). Randomisation (1:1): IDegAsp or IGlar IAsp. Intensification to twice daily (BID) was permitted W32, additional IAsp...
Heterozygous mutations in thyroid hormone receptor-beta (TRbeta) gene are the cause of resistance to (RTH) more than 85% families having syndrome. In 23% families, TRbeta occur de novo. Of 141 with RTH investigated by us, 21 (15%) had no detectable sequencing from genomic DNA (gDNA) or cDNA (non-TR RTH).The objective study was investigate genotype a family and correlate it phenotype.The isolated different tissues, sequence determined. Clinical studies involved administration incremental...
The influence of hypothyroidism on haemostasis is an active research area. Not only bleeding tendency but also hypercoagulable states have been reported in hypothyroid patients. Decreased and increased fibrinolytic activity patients has shown several studies. Thrombin activatable fibrinolysis inhibitor (TAFI) fibrinolysis, which recently isolated from human plasma. aim our study was to determine plasma TAFI antigen levels overt subclinical hypothyroidism, investigate the effect levothyroxine...