Tevfik Demir

ORCID: 0000-0003-0319-9572
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About
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Research Areas
  • Thyroid Disorders and Treatments
  • Diabetes and associated disorders
  • Thyroid Cancer Diagnosis and Treatment
  • Adrenal and Paraganglionic Tumors
  • Nuclear Structure and Function
  • Hormonal Regulation and Hypertension
  • COVID-19 Clinical Research Studies
  • Diabetes Treatment and Management
  • Hormonal and reproductive studies
  • Sexual function and dysfunction studies
  • Pituitary Gland Disorders and Treatments
  • Adrenal Hormones and Disorders
  • Blood Coagulation and Thrombosis Mechanisms
  • Diabetes Management and Research
  • Sexual Differentiation and Disorders
  • Vitamin D Research Studies
  • Metabolism, Diabetes, and Cancer
  • Cancer, Hypoxia, and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Gestational Diabetes Research and Management
  • Inflammasome and immune disorders
  • Bone health and treatments
  • RNA Research and Splicing
  • Growth Hormone and Insulin-like Growth Factors
  • Diabetes, Cardiovascular Risks, and Lipoproteins

Dokuz Eylül University
2015-2024

Izmir Bozyaka Eğitim ve Araştırma Hastanesi
2021

Education Training And Research
2021

Izmir Kâtip Çelebi University
2021

Istanbul University
2006-2017

Ege University
2017

Bursa Uludağ Üni̇versi̇tesi̇
2017

Dr. Behçet Uz Çocuk Hastalıkları Hastanesi
2017

Eskişehir Osmangazi University
2010-2013

Afyon Kocatepe University
2008-2011

This study assessed the effects of glucagon-like peptide-1 (GLP-1)/glucagon receptor co-agonist efinopegdutide relative to selective GLP-1 agonist semaglutide on liver fat content (LFC) in patients with non-alcoholic fatty disease (NAFLD).This was a phase IIa, randomized, active-comparator-controlled, parallel-group, open-label study. A magnetic resonance imaging-estimated proton density fraction assessment performed determine LFC at screening and Week 24. Participants an ≥10% were...

10.1016/j.jhep.2023.05.013 article EN cc-by-nc-nd Journal of Hepatology 2023-06-23

Aim: We wished to investigate the relationship between metabolic syndrome and erectile dysfunction (ED). Materials methods: A total of 268 patients were included in this study. All asked fill an International Index for Erectile Function (IIEF) questionnaire. The presence was determined when any three or more five risk factors present according National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP)‐III. factor ED status logistic regression analysis. Results: Eighty‐nine...

10.1111/j.1442-2042.2006.01310.x article EN International Journal of Urology 2006-04-01

Context: Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near-total lack of body fat. Objective: We aimed to study natural history and disease burden various subtypes CGL. Design: attempted ascertain nearly all patients with CGL in Turkey. Setting: This was nationwide study. Patients or Other Participants: Participants included 33 (22 families) 30 healthy controls. Main Outcome Measure(s): wanted genotypes sequencing the known genes....

10.1210/jc.2016-1005 article EN The Journal of Clinical Endocrinology & Metabolism 2016-05-04

We determine the prevalence of premature ejaculation in patients with hyperthyroidism and observed intravaginal latency time alterations before after treatment.Between January 2004 June 2007, 49 no history treatment were enrolled study. After obtaining a detailed sexual anamnesis an erectile function questionnaire was completed patient self-reported outcome measure difficult control over examined. assessed stopwatch measurements performed by or partner. Patient anxiety status also evaluated....

10.1016/j.juro.2008.10.150 article EN The Journal of Urology 2009-01-30

Coronavirus disease 2019 (COVID-19) has been reported to be associated with a more severe course in patients type 2 diabetes mellitus (T2DM). However, adverse outcomes are not recorded all patients. In this study, we assessed and without T2DM hospitalized for COVID-19.A nationwide retrospective cohort of confirmed COVID-19 infection from 11 March 30 May 2020 the Turkish Ministry Health database was investigated. Multivariate modeling used assess independent predictors demographic clinical...

10.1111/1753-0407.13171 article EN Journal of Diabetes 2021-03-03
Adnan Batman Dilek Yazıcı Oğuz Dikbaş Kemal Ağbaht Emre Sedar Saygılı and 87 more İbrahim Demirci Nurbanu Bursa Görkem Ayas Cüneyd Anıl Mustafa Cesur Fatma Nur Korkmaz Adile Begüm Bahçecioğlu Demet Çorapçıoğlu Murat Faik Erdoğan Hayri Bostan Murat Çalapkulu Sema Hepşen Bekir Uçan Erman Çakal Bağdagül Yüksel Güler Cem Haymana Süleyman Hilmi İpekçi Selami Aydın Havva Sezer Seçil Özışık Oğuzhan Deyneli Faruk Alagöl Refik Tanakol Mustafa Eroğlu Ümmü Mutlu Hülya Hacışahinoğulları Ayşe Kubat Üzüm Canan Demir Gönül Koç Sevde Nur Fırat Tülay Omma Nurcan İnce Şefika Burçak Polat Oya Topaloğlu Cevdet Aydın Bekir Çakır Çiğdem Tura Bahadır Mehmet Güven Mehmet Sözen Alev Selek Zeynep Cantürk Berrin Çetinarslan Mustafa Aydemir Işılay Taşkaldıran Yusuf Bozkuş Özlem Turhan İyidir Filiz Ekşi Haydardedeoğlu Seda Erem Basmaz Mehmet Çağrı Ünal Tevfik Demir Ayten Oğuz Özlem Çelik Merve Yılmaz Aykut Çimşir Serdar Kayıhan Ziynet Alphan Üç Sakin Tekin Ömercan Topaloğlu Başak Özgen Saydam Yasemin AYDOĞAN ÜNSAL Özge Özer Göknur Yorulmaz Kader Uğur Sezin Doğan Çakır Mehmet Aşık Mustafa Ünübol Selin Genç Burak Andaç Mine Okur Özlem Doğan Ersen Karakılıç Gökçen Ünal Kocabaş Cem Onur Kıraç Güven Barış Cansu Meliha Melin Uygur Zafer Pekkolay Sadettin S. Ozturk Aşkın Güngüneş Eren Gürkan Lezan Keskin Kenan Çağlayan Yasemin Günay Eren İmre Selçuk Yusuf Şener Ahmet Toygar Kalkan Deniz Engin Gök Mustafa Şahi̇n

Abstract Context The aims of the study are to compare characteristics subacute thyroiditis (SAT) related different etiologies, and identify predictors recurrence SAT incident hypothyroidism. Methods This nationwide, multicenter, retrospective cohort included 53 endocrinology centers in Turkey. participants were divided into either COVID-19–related (Cov-SAT), SARS-CoV-2 vaccine–related (Vac-SAT), or control (Cont-SAT) groups. Results Of 811 patients, 258 (31.8%) Vac-SAT group, 98 (12.1%)...

10.1210/clinem/dgad235 article EN The Journal of Clinical Endocrinology & Metabolism 2023-04-25

Abstract Background Lipodystrophy is a rare disease characterized by loss of adipose tissue. Natural history studies have demonstrated significant burden disease; however, there limited data on the impact lipodystrophy quality life (QoL) and psychoemotional well-being. The QuaLip study prospective observational real-world that aims to determine QoL well-being explore subjective disease. Sixty-seven adult patients eight pediatric with were included. Patients followed up for 24 months...

10.1186/s13023-023-03004-w article EN cc-by Orphanet Journal of Rare Diseases 2024-01-05

We aimed to evaluate the predictors of subsequent development postpartum carbohydrate intolerance, metabolic syndrome and cardiovascular risk factors in women with previous GDM. Two hundred fifty-two consecutive GDM were enrolled. After exclusion who did not attend hospital for follow-up visits minimum 1 year, data 195 patients evaluated. Seventy-one lean negative screening included as a control group. The prevalence diabetes, impaired glucose tolerance fasting was significantly higher than...

10.3109/09513590.2010.492885 article EN Gynecological Endocrinology 2010-06-14

AimsTo confirm non-inferiority of insulin degludec/insulin aspart (IDegAsp) once-daily (OD) versus glargine (IGlar) U100 OD + (IAsp) for HbA1c after 26 weeks, and compare efficacy safety between groups at W26 W38.MethodsA 38-week, randomised, open-label, treat-to-target (HbA1c < 7.0%) trial in adults with type 2 diabetes mellitus (on basal ± oral antidiabetic drugs; 7.0–10.0%). Randomisation (1:1): IDegAsp or IGlar IAsp. Intensification to twice daily (BID) was permitted W32, additional IAsp...

10.1016/j.diabres.2018.10.024 article EN cc-by-nc-nd Diabetes Research and Clinical Practice 2018-11-16

Heterozygous mutations in thyroid hormone receptor-beta (TRbeta) gene are the cause of resistance to (RTH) more than 85% families having syndrome. In 23% families, TRbeta occur de novo. Of 141 with RTH investigated by us, 21 (15%) had no detectable sequencing from genomic DNA (gDNA) or cDNA (non-TR RTH).The objective study was investigate genotype a family and correlate it phenotype.The isolated different tissues, sequence determined. Clinical studies involved administration incremental...

10.1210/jc.2006-0727 article EN The Journal of Clinical Endocrinology & Metabolism 2006-06-28

The influence of hypothyroidism on haemostasis is an active research area. Not only bleeding tendency but also hypercoagulable states have been reported in hypothyroid patients. Decreased and increased fibrinolytic activity patients has shown several studies. Thrombin activatable fibrinolysis inhibitor (TAFI) fibrinolysis, which recently isolated from human plasma. aim our study was to determine plasma TAFI antigen levels overt subclinical hypothyroidism, investigate the effect levothyroxine...

10.1507/endocrj.k06-062 article EN Endocrine Journal 2007-01-01
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