A5026072872- Antibiotic Resistance in Bacteria
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Pneumonia and Respiratory Infections
- Antimicrobial Resistance in Staphylococcus
- Antifungal resistance and susceptibility
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial Infections and Vaccines
- Bacterial biofilms and quorum sensing
- Vibrio bacteria research studies
- Infections and bacterial resistance
- Neonatal and Maternal Infections
- Escherichia coli research studies
- Fungal Infections and Studies
- Chronic Lymphocytic Leukemia Research
- Nosocomial Infections in ICU
- Salmonella and Campylobacter epidemiology
- Yersinia bacterium, plague, ectoparasites research
- Infective Endocarditis Diagnosis and Management
- Urinary Tract Infections Management
- Plant Pathogens and Fungal Diseases
- Pharmaceutical and Antibiotic Environmental Impacts
- Heparin-Induced Thrombocytopenia and Thrombosis
- Oral health in cancer treatment
Karadeniz Technical University
2012-2024
University of Kara
2012
Ministry of Health
2012
Psychiatric Association of Turkey
2012
Janssen (Switzerland)
2011
A multiple-locus variable-number tandem-repeat analysis (MLVA) was applied to investigate the epidemiological relationship and genetic diversity among 162 human Brucella isolates collected from all geographic regions of Turkey in an 8-year period (2001 2008). The were genotyped by using MLVA assay developed Orsay, France (MLVA-16(Orsay)) including eight minisatellite (panel 1) microsatellite 2, subdivided into 2A 2B) markers. Panels 1 distinguish 14 genotypes; two these represented 85%...
ObjectivesDoripenem is a new carbapenem recently introduced into Europe. The COMParative Activity of Carbapenem Testing (COMPACT) study compared the susceptibility common Gram-negative bacilli causing serious infections in hospitalized patients with doripenem, imipenem and meropenem.
Carbapenems are the choice of treatment in infections caused by multidrug resistant Enterobacteriaceae. In recent years carbapenem-resistant Enterobacteriaceae isolates due to carbapenemases have been increasingly reported worldwide. Multicenter studies on scarce Turkey. The aim this study was determine distribution from different parts Turkey as a part European Survey Carbapenemase Producing (EuSCAPE) project. Beginning November 2013, at least one agents, namely imipenem, meropenem, and...
It was recently proposed that Candida parapsilosis represents a complex composed of three closely related species, i.e., C. sensu stricto, orthopsilosis, and metapsilosis. The aim this study to describe the distribution isolates among clinical samples. We also evaluated antifungal susceptibility profiles, in vitro presence lipase secreted aspartyl proteinase, as well their ability grow total parenteral nutrition (TPN) solution, biofilm production. A 413 non-C. albicans were obtained from...
Serratia marcescens is a well-known but relatively uncommon cause of nosocomial infections, particularly in neonatal intensive care unit (NICU) patients. We investigated an outbreak S the NICU at Farabi Hospital Karadeniz Technical University Trabzon, Turkey.Between March 21 and May 27, 2006, nine neonates were identified with cultures marcescens, there three deaths because septicemia. For purpose identifying source infection, 85 environmental samples, two breast milk samples from babies'...
Objective To evaluate the serotype distribution and antibiotic resistance in pneumococcal infections adults to provide a perspective regarding coverage of both current future vaccines.Patients methods This passive surveillance study was conducted with Streptococcus pneumoniae strains isolated from specimens patients pneumonia (materials bronchoalveolar lavage), bacteraemia, meningitis, pleuritis peritonitis between 2015 2018. Serogrouping serotyping were performed by latex particle...
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most important nosocomial pathogens and also emerging in Turkish hospitals. The aim this study was to determine antimicrobial susceptibility profiles MRSA isolated from hospitals.A total 397 strains 12 hospitals Turkey were included present study. Antimicrobial susceptibilities tested using agar dilution method. Presence ermA, ermB, ermC, msrA, tetM, tetK, linA aac-aph genes studied by PCR.All susceptible vancomycin linezolid....
It is controversial to test for urinary tract infection (UTI) in patients with unexplained indirect hyperbilirubinemia the first 2 weeks of life. We aimed study prevalence and significance UTIs such neonates who were requiring phototherapy.Subjects 2- 14-day-old bilirubin levels above phototherapy limit no other abnormality their bilirubinaemia-related etiologic workup. UTI was diagnosed by consecutive positive cultures obtained catheterisation, documenting growth >10,000 colonies same...
Successful vaccination policies for protection from invasive pneumococcal diseases (IPD) dependent on determination of the exact serotype distribution in each country. We aimed to identify serotypes strains causing IPD children Turkey and emphasize change before after with 7-valent conjugate vaccine (PCV-7) was included PCV-13 newly changed Turkish National Immunization Program. Streptococcus pneumoniae were isolated at 22 different hospitals Turkey, which provide healthcare services...
This study presents data on species distribution and antifungal susceptibility profiles of Candida bloodstream isolates obtained from a Turkish Tertiary Care Hospital during 4-year period. All hospitalized patients who had ≥ 1 blood culture positive for yeast their hospital stay January 2005 through 2009 were included in this study. identified to level using CHROMagar ID 32 C. Fluconazole voriconazole testing was performed the disk diffusion method according CLSI M44-A. In vitro activity...
Stenotrophomonas maltophilia, which is a non-fermentative gram-negative bacillus, has an increasing importance in nosocomial and opportunistic infections. Since it exhibits resistance to numerous broad-spectrum antibiotics such as aminoglycosides, beta-lactams tetracyclines, may considerably limit empirical treatment options. Trimethoprim-sulfamethoxazole (SXT) recommended the first-line therapy of S.maltophilia infections thanks its high potency usefulness range patients. In recent years,...
A rapid, practical, and accurate identification of carbapenemase-producing Enterobacteriaceae isolates is crucial for the implementation appropriate infection control measures proper treatment infections. For this purpose, a large number phenotypic test methods have been developed, although none has 100% sensitivity specificity. Variations in specificity these tests based on type beta-lactamase enzymes carried by that might result differences between regions countries. The aim study was to...
To investigate changes in antibiotic susceptibility of Streptococcus pneumoniae and Haemophilus influenzae from the Survey Antibiotic Resistance (SOAR) community-acquired respiratory tract infections (CA-RTIs) between 2002 2009 Turkey.Previously published SOAR data were used for this analysis. MICs determined using Etest(®) gradient strips or disc diffusion. Susceptibility against a range antimicrobial agents was assessed CLSI breakpoints.A total 900 S. isolates analysed: 2002-03 (n = 75),...
The aim of the study was to evaluate relationship between carbapenem-resistant Acinetobacter baumannii isolates carrying oxacillinase-type carbapenemase genes with "international high-risk clones" (IC I, II, and III) by different molecular epidemiological methods statistically compare concordance discrimination power methods. Carbapenem-resistant moderately susceptible A.baumannii from non-repeating blood cultures 72 patients were included in study. presence "blaOXA-23 , blaOXA-24 blaOXA-51...
Staphylococcus aureus is one of the most frequent agents causing hospital infections. S.aureus has a great ability to adapt itself variety conditions and successful clones can be epidemic even pandemic by its spread from continent another. The aims this study were detect spa types 397 methicillin-resistant (MRSA) strains isolated 12 centers in different geographical regions Turkey 2006 2008, investigate their clonality PFGE MLST typing. Additionally, 91 MRSA four those during 2011 also...
One of the treatment options Escherichia coli and Klebsiella spp. infections which are most common opportunistic pathogens gram-negative sepsis is quinolones. Resistance to quinolones act by disrupting DNA synthesis has been increasing. Horizontal transfer plasmid-mediated quinolone resistance (PMQR) genes play an important role in spread resistance. The data about prevalence PMQR our country quite limited. aim this study was investigate presence known namely qnrA, qnrB, qnrC, qnrS, qnrD,...
Objective: Neonatal sepsis, especially nosocomial sepsis (NS) is one of the main causes mortality and morbidity in neonates. Our aim was to investigate microorganisms responsible for NS antimicrobial susceptibility patterns compare them a different period.Methods: Blood culture registers from Microbiology Laboratory were reviewed study population. The neonates with proven enrolled study. Microorganisms recordedResults: incidence Gram-positive, Gram-negative, fungal 61.6% (n = 570), 27.1%...