- Pediatric Urology and Nephrology Studies
- Metabolism and Genetic Disorders
- Eosinophilic Esophagitis
- Renal and Vascular Pathologies
- Streptococcal Infections and Treatments
- Vascular anomalies and interventions
- Dialysis and Renal Disease Management
- Gastrointestinal disorders and treatments
- Eosinophilic Disorders and Syndromes
- Neonatal Health and Biochemistry
- Cardiac Imaging and Diagnostics
- Chronic Kidney Disease and Diabetes
- Coronary Artery Anomalies
- Human Health and Disease
- Liver Disease Diagnosis and Treatment
- Transplantation: Methods and Outcomes
- Acute Kidney Injury Research
- Bladder and Urothelial Cancer Treatments
- Renal function and acid-base balance
- Urinary Bladder and Prostate Research
- Kidney Stones and Urolithiasis Treatments
- Adenosine and Purinergic Signaling
- Urinary Tract Infections Management
- Cancer, Hypoxia, and Metabolism
- Renal Diseases and Glomerulopathies
Karadeniz Technical University
2014-2024
Koç University
2019-2021
Pediatric Nephrology of Alabama
2012-2019
Johns Hopkins Medicine
2018
Johns Hopkins University
2018
Pediatrics and Genetics
2014
Harefield Hospital
1990-1992
It is controversial to test for urinary tract infection (UTI) in patients with unexplained indirect hyperbilirubinemia the first 2 weeks of life. We aimed study prevalence and significance UTIs such neonates who were requiring phototherapy.Subjects 2- 14-day-old bilirubin levels above phototherapy limit no other abnormality their bilirubinaemia-related etiologic workup. UTI was diagnosed by consecutive positive cultures obtained catheterisation, documenting growth >10,000 colonies same...
Objectives. This study aimed to demonstrate if the addition of anti-inflammatory treatment antibiotic therapy shows any superiority with only. Methods. Forty-nine Wistar rats were divided into 7 groups. Pyelonephritis was performed by E. coli injection upper pole kidneys except control group. Group 2 not treated. Ceftriaxone, ketoprofen, “ceftriaxone + ketoprofen,” methylprednisolone, and methylprednisolone” given in The technetium-99m-dimercaptosuccinic acid scintigraphies 3rd day detect...
Eosinophilic cystitis is a rare inflammatory disease of the bladder; it rarely occurs in children. Patients typically show irritative urination symptoms frequently, with possible need for urgency, alongside dysuria, gross haematuria, suprapubic pain and painful urination. Sometimes bladder mass accumulation possibility malignancy also observed. We present an 8-year-old male patient who gained admission terminal hematuria discuss management eosinophilic cystitis.
INTRODUCTION: To describe the clinical and laboratory profile, natural course, treatment outcome, risk factors of posttransplant esophageal nonesophageal eosinophilic gastrointestinal disorders (EGIDs). METHODS: All children (aged <18 years) who underwent liver transplantation, between 2011 2019, in a single transplant center with follow-up period 1 year or more history endoscopic evaluation were included this study. RESULTS: During study period, 89 met inclusion criteria. Patients...
Background Neurological involvement is common in hemolytic uremic syndrome (HUS), but each neurological symptom may be due to a variety of factors. Objective We aimed evaluate predisposing factors the symptoms HUS. Materials and Methods The 10-year follow-up data on HUS patients were retrospectively analyzed. Statistical comparisons made across subgroups based age symptoms. Results rate was 37.5%. female-to-male ratio increased with (3.8 vs. 1.37). Regarding all patients, hemoglobin levels...
To define the incidence, possible causes, operative procedure, and early medium term results of patients undergoing reoperation for coronary artery disease.A retrospective analysis in one hospital during a 10 year period.A regional cardiothoracic centre.115 had recurrent angina, 1-17 years (mean (SD) 7.4 (3.9)) after primary revascularisation.They received 279 grafts (2.4 per patient); 58% were anasatomosed to previously grafted vessels. The internal mammary was used 87% who required left...
Objective: Infections are major causes of morbidity and mortality in burn patients.The most common infections include wound infection, bloodstream infections, sepsis.Pseudomonas aeruginosa Staphylococcus aureus the organisms.The aim this study was to determine epidemiological characteristics patients, burns, responsible microorganisms, treatment strategies.Methods: This a cross-sectional study.The medical records patients aged between 1 month 18 years 2012-2018 were retrospectively...
Ataxia-telangiectasia (AT) is a hereditary recessive autosomal disorder following course of progressive cerebellar ataxia, and oculocutaneous telangiectasia. Disease-specific telangiectasias are generally localized in the region, while located within bladder rarely seen patients with AT. The patient who had been followed-up diagnosis AT since age 3 years was later diagnosed acute lymphoblastic leukemia at 8 years. developed hematuria approximately 29th month treatment. cystoscopy revealed...
Gastrointestinal bleeding is a rare but potentially life-threatening manifestation of eosinophilic gastrointestinal disorders (EGIDs). Here, we describe case series comprising 5 pediatric patients between 7 and 12 years age, who presented to the emergency department with hematemesis were subsequently diagnosed EGID. Accompanying allergic history, peripheral eosinophilia, total IgE elevation common. Despite more severe presentation, response medical dietary therapy was favorable. A...
The presented study aimed to evaluate the utility of magnetic resonance angiography (MRA) in pediatric population with nutcracker syndrome.Patients suggestive clinical symptoms and laboratory findings got diagnosis syndrome Doppler ultrasonography between January 2011–2019 were included study. In addition, children who had renal MRA due hypertension evaluated as control group. images all patients examined retrospectively by three radiologists at different levels experience, superior...
Shiga toxin–producing Escherichia coli (STEC) refers to a group of bacteria that can cause infections, which are common worldwide and pose serious public health problem, as they lead conditions such hemorrhagic colitis hemolytic uremic syndrome (HUS). HUS is disease characterized by microangiopathic anemia, thrombocytopenia, renal failure. Determination serogroups toxin profiles STEC important for estimating their disease-causing potential predicting epidemiological changes. This study...
Background. Previous studies demonstrated critical deficits in diagnosis and management of childhood food allergy (FA), recent developments FA research support adopting a proactive approach management. Our objective was to describe knowledge patterns pediatricians. Method. We applied 24-item survey 170 general pediatricians, pediatric allergists gastroenterologists practicing Turkey. Results. Some IgE-mediated symptoms such as cough, urticaria, wheezing anaphylaxis were falsely recognized...
Background. Atypical hemolytic uremic syndrome (aHUS) occurs due to defective regulation of the alternative complement pathway (ACP) on vascular endothelial cells. Plasma based therapy (PT) was mainstay treatment for aHUS many years until introduction therapies targeting blockage system. The aim this study evaluate patients with who had been treated plasma alone. Methods. outcomes seven genetically confirmed (2 girls, 5 males) were evaluated by means clinical presentation, response therapy,...
What is known and objective Erlotinib a small molecule tyrosine kinase inhibitor which blocks the activation of epidermal growth factor receptor (EGFR), transmembrane that upregulated in many cancer types. Inhibition angiogenesis with consequent impairments intratumoral microcirculation one mechanisms through EGFR inhibition halts progression cancer. A consequence impaired hypoxia, results increases serum uric acid levels. The goal this study was to investigate relationship between levels...
Varicella infections are usually considered to be benign. Although very rare, infection of an immunocompetent patient by this virus may result in a severe illness. We describe case varicella previously healthy, 5-y-old boy, complicated with compartment syndrome, disseminated intravascular coagulation (DIC), pneumonia, and acute renal failure. He was treated successfully aciclovir intravenous immunoglobulins for the infection, fasciotomy fresh frozen plasma DIC.