A5023551520- Renal Diseases and Glomerulopathies
- Pediatric Urology and Nephrology Studies
- Biomedical Research and Pathophysiology
- Autoimmune and Inflammatory Disorders Research
- Complement system in diseases
- Kidney Stones and Urolithiasis Treatments
- Urological Disorders and Treatments
- Neonatal Health and Biochemistry
- Adolescent and Pediatric Healthcare
- Vasculitis and related conditions
- Adenosine and Purinergic Signaling
- Inflammasome and immune disorders
- Urinary Tract Infections Management
- Vascular anomalies and interventions
- Systemic Lupus Erythematosus Research
- Acute Kidney Injury Research
- Kawasaki Disease and Coronary Complications
- Endoplasmic Reticulum Stress and Disease
- Ocular Diseases and Behçet’s Syndrome
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Cerebrovascular and genetic disorders
- Retinal and Optic Conditions
- Streptococcal Infections and Treatments
Ondokuz Mayıs University
2018-2024
Ministry of Health
2013-2023
Sağlık Bilimleri Üniversitesi
2020
Dr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi
2015-2018
Wolfram Research (United States)
2015
Başkent University
2015
Boston Children's Hospital
2013-2014
To report sarcoid-like uveitis with or without tubulointerstitial nephritis (TIN) during coronavirus disease 2019 (COVID-19) and to discuss diagnostic evaluation treatment.Detailed information on the subject's demographics, medical history, ophthalmic examination findings, laboratory results were obtained from records. Fluorescein angiography (FA) indocyanine green (ICGA) images evaluated.All seven patients aged between 8 17 had bilateral granulomatous panuveitis. TIN preceded in four...
To evaluate the underlying causes and outcomes of neonates who underwent acute peritoneal dialysis (APD).This report describes a 7-year experience with APD in 77 neonates.Underlying requiring were tubular necrosis (ATN; n = 53), inborn error metabolism (n 18), bilateral renal vein thrombosis 3), obstructive uropathy 2; posterior urethral valve neurogenic bladder), artery 1). Fifteen 53 patients developed post-cardiac surgery ATN. The mean duration was 6.2 ± 10.7 days (range 1 to 90 days)....
To investigate the demographic, clinical and laboratory data of children with idiopathic nephrotic syndrome (INS), to determine prognostic factors that affect outcome patients.Medical charts 372 patients diagnosed have INS followed up at least 5 years between January 1990 December 2008 were evaluated, respectively. After initial findings documented, therapeutic protocols, prognosis investigated.299 (80.4%) steroid responsive 73 (19.6%) not. Focal segmental glomerulosclerosis (FSGS) was...
Background Congenital anomalies of the kidney and urinary tract (CAKUT) are defined as structural malformations and/or tract. Heat shock proteins (HSPs) expressed in response to cellular changes, such thermal, hemodynamic, osmotic, inflammatory, mechanical stresses. This study aimed assess uHSP70 levels during acute infections (UTI) non-infection periods patients with CAKUT, evaluate whether is elevated CAKUT subtypes. Methods Among 89 UTI (CAKUT-A), 111 without (CAKUT-B), 74 healthy...
Abstract Background The aim of this study was to identify the cut‐offs postnatal anteroposterior renal pelvic diameter ( APRPD ), according urinary tract dilation UTD ) classification system, predictors final diagnosis and need for surgery. Methods A total 260 infants (336 units) with prenatally detected were prospectively evaluated on serial ultrasonography by same radiologist. Additional voiding cystourethrography scintigraphy done clinical algorithm. Results Prenatal in patients transient...
Juvenile idiopathic arthritis (JIA) is the commonest chronic rheumatic disease among children. When not treated effectively, JIA can lead to functional disability, due joint damage, along with long-term morbidities.To describe use of tocilizumab therapy for 11 patients polyarticular (pJIA) and systemic (sJIA) who presented inadequate response or were refractory disease-modifying anti-rheumatic drugs (DMARDs) and/or other biological therapies; evaluate its benefits, safety...
Acute kidney injury (AKI) is an important clinical condition that associated with increased mortality and morbidity. This study was performed to identify the factors influence AKI stage, undergoing renal replacement therapy (RRT) mortality.This retrospectively conducted on 219 children who had been referred paediatric nephrology division of Dr Sami Ulus Teaching Hospital during their inpatient treatment from 2008 2012. defined using pRIFLE criteria.From enrolled patients, 131 were identified...
Background: The prognostic factors, the outcome and most favorable treatment regimen are not entirely known for children with membranoproliferative glomerulonephritis (MPGN). MPGN is a rarely observed disease more prevalent in adolescents, so we aimed to review clinical histological properties, treatments of our patients who were diagnosed as MPGN. Methods: Fifty-one – selected from biopsy records Dr. Sami Ulus Maternity Children's Hospital Pediatric Nephrology Department January 1999 2011....
Introduction This report provides insight into three distinct pediatric cases exhibiting a nexus between multisystem inflammatory syndrome in children (MIS-C) and thrombotic microangiopathy (TMA) triggered by COVID-19. The aim is to underscore the range of clinical presentations essentiality early interventions. Case presents aged 10 months, 7 years, 3 years with persistent fever, diarrhea, nausea, vomiting. first case, 10-month-old girl, demonstrated acute kidney injury (AKI)...
To investigate the renal expression of apoptosis regulatory proteins b-cell lymphoma 2 (bcl-2) and bcl-2 associated X (bax) in children with Henoch–Schönlein nephritis (HSN) Materials methods: Renal antiapoptotic proapoptotic bax were studied immunohistochemically 22 HSN. The kidneys 5 who died due to nonrenal reasons used as control. patients compared according their histopathology prognosis. Results: Nephrotic or nephrotic-nephritic involvement was most common presentation....
Background. Atypical hemolytic uremic syndrome (aHUS) occurs due to defective regulation of the alternative complement pathway (ACP) on vascular endothelial cells. Plasma based therapy (PT) was mainstay treatment for aHUS many years until introduction therapies targeting blockage system. The aim this study evaluate patients with who had been treated plasma alone. Methods. outcomes seven genetically confirmed (2 girls, 5 males) were evaluated by means clinical presentation, response therapy,...
Amaç: Hematüri çocuklarda üriner sistem hastalıklarının önemli bir bulgusudur. Altta yatan ciddi hastalıkların belirtisi olabileceğinden ayırıcı tanı için dikkatli değerlendirme ve iyi klinik yaklaşım gerektirmektedir. Bu çalışmada pediatrik nefroloji kliniğimize hematüri nedeni ile başvuran hastaların demografik özellikleri nin incelenmesi tanıya yol gösterecek özelliklerin belirlenmesi amaçlandı. Hastalar Yöntem: çalışma, kliniğimizde makroskopik ve/veya mikroskopik nedeniyle izlenmiş olan...
hastalıkta fenotip-genotip ilişkisi kurmak zordur.Aynı mutasyon çok farklı fenotiplere neden olabilmektedir (2)