A5102859573- Autoimmune and Inflammatory Disorders Research
- Adolescent and Pediatric Healthcare
- Kawasaki Disease and Coronary Complications
- Systemic Lupus Erythematosus Research
- Renal Diseases and Glomerulopathies
- Immunodeficiency and Autoimmune Disorders
- Eosinophilic Esophagitis
- Coronary Artery Anomalies
- Inflammasome and immune disorders
- Mechanical Circulatory Support Devices
- Pharmacological Effects and Toxicity Studies
- Ocular Diseases and Behçet’s Syndrome
- Blood disorders and treatments
- Otitis Media and Relapsing Polychondritis
- Child Development and Digital Technology
- Renal cell carcinoma treatment
- Pediatric health and respiratory diseases
- Hemoglobinopathies and Related Disorders
- Epilepsy research and treatment
- COVID-19 Clinical Research Studies
- Peripheral Artery Disease Management
- Cardiovascular Issues in Pregnancy
- Peripheral Neuropathies and Disorders
- Pregnancy and Medication Impact
- Streptococcal Infections and Treatments
Dr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi
2022-2025
Memorial Ankara Hospital
2024-2025
Ministry of Health
2012-2023
Sağlık Bilimleri Üniversitesi
2021
Ankara University
2017
Abstract Background Juvenile idiopathic arthritis (JIA) is a prevalent childhood chronic arthritis, often persisting into adulthood. Effective transitional care becomes crucial as these patients transition from pediatric to adult healthcare systems. Despite the concept of being recognized, its real-world implementation remains inadequately explored. This study aims evaluate thoughts and practices providers regarding for JIA patients. Methods A cross-sectional survey was conducted among...
Objective The study aimed to report the efficacy and safety of anakinra treatment in patients with refractory multisystemic inflammatory syndrome children (MIS-C). Methods This is a cross-sectional retrospective consisting pediatric diagnosed MIS-C who were treated anakinra. Results Among 378 MIS-C, 82 (21.6%) included study. median age was 115 (6-214) months. duration hospitalization 15 (6-42) days. Sixty (73.1%) admitted intensive care unit. Patients dose 2.7 mg/kg/day concomitant IVIG...
Background: Interleukin-10 (IL-10) is a crucial anti-inflammatory cytokine essential for maintaining immune homeostasis, particularly in the gastrointestinal system. Defects IL-10 signaling pathway, including mutations interlaukin-10 receptor (IL-10R) beta, have been implicated early-onset inflammatory bowel disease (IBD), often resistant to conventional treatments. Case Presentation: We report 1.5-month-old male patient with IL-10R beta deficiency presenting fever, vomiting, malnutrition,...
Cyclophosphamide (CYC) is an inactive alkylating agent that transforms the alkyl radicals into other molecules and used in combination with systemic corticosteroids treatment of many childhood rheumatic diseases, such as lupus erythematosus (SLE), ANCA-associated vasculitis (AAV). In recent years, rituximab (RTX), a B-cell-targeting anti-CD20 monoclonal antibody, has emerged new alternative modality over CYC for induction therapy childhood-onset diseases. Clinicians adopt different practices...
Aim Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection may result in a life‐threatening hyperinflammatory condition named multisystem inflammatory children (MIS‐C). We aimed to assess demographics, clinical presentations, laboratory characteristics and treatment outcomes of patients with MIS‐C. Methods performed retrospective study MIS‐C managed between August 2020 March 2021 at Dr. Sami Ulus Maternity Child Health Diseases Training Research Hospital Turkey. Results A...
The aim of this study was to evaluate the outcomes patients with multisystem inflammatory syndrome in children (MIS-C) according phenotypes disease and define prognostic factors for severe course. This cross-sectional included 293 MIS-C from seven pediatric rheumatology centers. A two-step cluster analysis performed spectrum their were compared between each group. Four subgroups identified as follows: I, predominantly Kawasaki-like features (n = 100); II, MAS-like 34); III, LV dysfunction...
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome (PFAPA) is the most common periodic fever condition in children. There no consensus on treatment to prevent attacks reduce their frequency. In this study, we aimed evaluate effectiveness of colchicine PFAPA syndrome. addition, described demographic clinical features patients.
Pediatric-onset systemic lupus erythematosus is among the prototypic autoimmune diseases seen in children. Although neuropsychiatric involvement rate varies during course of disease, it an important cause morbidity and mortality. The clinical picture SLE (NPSLE) highly variable, neurological features can precede findings, leading to some diagnostic difficulties. NPSLE requires early aggressive immunosuppressive therapy. Some patients be resistant Chorea a rare manifestation that occurs...
The field of transitional care for chronic conditions in adolescents, notably juvenile idiopathic arthritis (JIA), is rapidly growing. Transitioning these patients to adult healthcare systems presents significant challenges practical implementation. Consequently, it would be appropriate each country develop a transition program tailored its specific infrastructure. To pursue this goal, Delphi study was conducted identify the key components JIA. Three panels and two rounds were held...
ABSTRACT: Objective: Juvenile idiopathic arthritis (JIA) is the most common autoimmune and familial Mediterranean fever (FMF) autoinflammatory chronic rheumatic disease in childhood. We aimed first to identify developmental behavioral problems of preschool-age children with diseases, second compare diagnostic categories, third elucidate associated factors these difficulties. Method: Of 91 participants included this study, 46 were diseases (27 JIA 19 FMF) 45 healthy children. The general...
Amaç: Juvenil idiyopatik artrit (JİA), çocukluk çağının en sık görülen kronik romatizmal hastalığıdır. Metotreksat (MTX), leflunomid (LFN) gibi hastalık modifiye edici antiromatizmal ilaçlar (DMARD) JİA'da birinci basamak tedavilerdir. MTX reçete edilen ilaçtır ve çalışmalar ağırlıklı olarak etkinliğini güvenliğini ele almaktadır. Ancak LFN ile ilgili veriler sınırlıdır. Bu çalışmada, JİA hastalarında tedavisi kliniğimizin deneyimlerini sunmayı amaçladık. Gereç Yöntem: retrospektif çalışmaya...
Objective : We aimed to investigate the efficacy of mycophenolate mofetil (MMF) for maintaining remission and reduce number relapses in childhood steroid-sensitive nephrotic syndrome. The effects MMF on growth blood pressure parameters were also evaluated. Material Methods: This retrospective, single-center observational study included patients with syndrome who treated using between 2009 2019 Department Pediatric Nephrology our hospital. Results: Ten had steroid-dependent syndrome; six...
Behçet’s disease (BD) is a multisystemic inflammatory with unknown etiology. It characterized by recurrent oral and genital ulcerations, uveitis, skin lesions, various musculoskeletal, gastrointestinal, central nervous system, vascular manifestations. The aim of this study was to analyse the demographic characteristics clinical features, treatment in Turkish paediatric BD from single center experience. records 36 patients who were diagnosed according International Study Group criteria...