A5085743117- Inflammasome and immune disorders
- Autoimmune and Inflammatory Disorders Research
- Ocular Diseases and Behçet’s Syndrome
- Kawasaki Disease and Coronary Complications
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Streptococcal Infections and Treatments
- Gout, Hyperuricemia, Uric Acid
- Osteomyelitis and Bone Disorders Research
- Renal Diseases and Glomerulopathies
- Eosinophilic Disorders and Syndromes
- Otitis Media and Relapsing Polychondritis
- Infectious Diseases and Tuberculosis
- IgG4-Related and Inflammatory Diseases
- Spondyloarthritis Studies and Treatments
- Mast cells and histamine
- Dermatological and COVID-19 studies
- Immunodeficiency and Autoimmune Disorders
- Urticaria and Related Conditions
- Genital Health and Disease
- Systemic Sclerosis and Related Diseases
- Adolescent and Pediatric Healthcare
- IL-33, ST2, and ILC Pathways
- Orthopedic Infections and Treatments
- Mechanical Circulatory Support Devices
Ankara University
2018-2025
Memorial Ankara Hospital
2019-2024
Antalya Eğitim ve Araştırma Hastanesi
2023
Sağlık Bilimleri Üniversitesi
2017-2022
City Hospital
2022
Selçuk Üniversitesi Tıp Fakültesi Hastanesi
2021
Ankara Mevki Asker Hastanesi
2021
Ministry of Health
2016-2021
University of Health Sciences
2021
Bilkent University
2021
Background Familial Mediterranean fever (FMF) is the most common hereditary monogenic autoinflammatory disease caused by mutations in MEFV gene. It controversial whether E148Q alteration an insignificant variant or a disease‐causing mutation. The aim of this study was to evaluate clinical features and severity FMF patients carrying Methods Files were retrospectively evaluated. Patients with at least one mutation included study. characteristics who only compared compound heterozygous for...
Abstract Aims Recently, multisystem inflammatory syndrome in children (MIS‐C) has been recognized association with coronavirus disease 2019 as a cytokine storm syndrome. MIS‐C presents symptoms similar to Kawasaki and macrophage activation (MAS). We aimed better understand this by comparing the initial laboratory findings of MAS. Methods Patients who were diagnosed MAS due systemic juvenile idiopathic arthritis our clinic between March 2002 November 2020 20 September October enrolled into...
Cyclophosphamide (CYC) is an inactive alkylating agent that transforms the alkyl radicals into other molecules and used in combination with systemic corticosteroids treatment of many childhood rheumatic diseases, such as lupus erythematosus (SLE), ANCA-associated vasculitis (AAV). In recent years, rituximab (RTX), a B-cell-targeting anti-CD20 monoclonal antibody, has emerged new alternative modality over CYC for induction therapy childhood-onset diseases. Clinicians adopt different practices...
Abstract Introduction Rheumatological diseases (RD) in childhood are systemic that occur on the basis of auto-immunity or inflammation, and they can be accompanied by inflammatory bowel disease (IBD). When there is no knowledge this association, treatments applied may not sufficient and/or given for RD even lead to aggrevation IBD findings. Thus, early identification an association crucial correct management diseases. Objectives The aim study show frequency patients with RDs. We also aimed...
Accumulation of free radicals in the epidermis and role oxidative stress have been demonstrated pathogenesis vitiligo. So, new treatment modalities that support antioxidant systems may be a choice for treatment. We sought to determine clinical efficacy narrow band ultraviolet B plus topical formulation including Cucumis melo superoxide dismutase catalase (Vitix), over alone. Thirty vitiligo patients (18 female, 12 male; mean age 34 +/- 13 years) were included this study. 15 Group 1 treated...
Familial Mediterranean fever (FMF) is an autosomal recessive disease, characterized by recurrent, self-limited attacks of with serositis. Various diseases were reported to be associated FMF. The aim this study was investigate the frequency and characteristics sacroiliitis in children FMF.Files FMF patients who had been seen 2 reference hospitals Ankara retrospectively evaluated. Patients concomitant included study. All magnetic resonance imaging evidence sacroiliitis.Among 650 patients, 17...
Background: Blood neutrophil to lymphocyte ratio (NLR) and mean platelet volume (MPV) both have been used as a simple marker of inflammation in many disorders. Here, we aimed investigate the relationship between NLR, MPV, familial Mediterranean fever (FMF). Materials Methods: In this retrospective study, files FMF patients pediatric rheumatology outpatient clinic were reviewed. There 160 participants (68.4%) patient group 74 (31.6%) control group. Ninety attack-free period, 70 attack period....
The aims of this study were to evaluate the role biological agents in treatment severe multisystem inflammatory syndrome children (MIS-C) and assess current application, outcomes, adverse effects patients who are followed up a pediatric intensive care unit (PICU).This observational, descriptive, medical records review was performed on with MIS-C admitted PICU between September 1 November 1, 2020. Through review, we confirmed that positive for or recent SARS-CoV-2 infection COVID-19 exposure...
Background: The Nd:YAG laser has been considered the gold standard of treatment for leg veins, but pain and side effects have fueled physicians to use alternatives. Objective: To compare clinical efficacy long-pulsed 1064-nm with KTP irradiation in telangiectasia. Methods: A series 16 patients size-matched superficial telangiectases lower extremities were randomly assigned receive three consecutive monthly treatments on one 532-nm other. Results: For who completed study, 64 vein sites...
Nailfold capillaroscopy is used for the identification of microvascular involvement in many rheumatic and extrarheumatic diseases.To determine nailfold capillary changes patients with Behçet disease (BD) by videodermoscopy, i.e. videocapillaroscopy (NVC).We a videodermatoscope (Molemax II, × 30 magnification) to perform on 40 BD healthy controls (HC). All images were evaluated density, distribution morphology, assessing features such as enlargement or tortuosity capillaries,...
Abstract Aim The aim of this study is to evaluate the clinical parameters, acute‐phase reactants, side effects, genetic mutations among colchicine‐resistant Familial Mediterranean fever (FMF) patients who received anti‐interleukin‐1 (anti‐IL‐1) treatment. We also quality life and school attendance FMF patients, in relation treatment with anti‐IL‐1. Introductıon most common inherited autoinflammatory disorder. Although main colchicine, a small group are resistant colchicine Anti‐IL‐1...
Objectives: Familial Mediterranean fever (FMF) is an autosomal recessive disease, characterized by recurrent, self limited attacks of with serositis. The aim this study was to describe the frequency musculoskeletal complaints in children FMF and investigate effect genotype on these findings.Methods: Files patients who had been seen our department (during routine follow-up visits) were retrospectively evaluated. Comparisons regarding findings performed between homozygous/compound heterozygous...
Adverse effects of desensitization injections mostly consist local transient reactions. Rarely, persistent subcutaneous nodular lesions may also develop at the site injection. These reactions have been attributed to vaccines containing aluminium hydroxide. Aluminium hydroxide is used as an adjuvant in and hyposensitization solutions. We describe a patient who presented persistent, itchy nodules reaction allergen immunotherapy for treatment allergic asthma.