- Adrenal Hormones and Disorders
- Inflammasome and immune disorders
- Immunodeficiency and Autoimmune Disorders
- Myasthenia Gravis and Thymoma
- Renal Diseases and Glomerulopathies
- Lung Cancer Research Studies
- Diabetes and associated disorders
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Galectins and Cancer Biology
- Chronic Lymphocytic Leukemia Research
- Platelet Disorders and Treatments
- T-cell and B-cell Immunology
- Atherosclerosis and Cardiovascular Diseases
- Protein Tyrosine Phosphatases
- Autoimmune and Inflammatory Disorders Research
- Urticaria and Related Conditions
Ege University
2020-2024
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi
2023
Uniwersytecki Szpital Dziecięcy
2020
Introduction. Most patients with primary and secondary immunodeficiencies need regular Intravenous Immunoglobulin (IVIG) or Subcutaneous (SCIG) treatment. This study aimed to evaluate the serum IgG trough levels, frequency of mild severe infections, duration hospitalization, absence school, quality life in switching their IVIG therapy SCIG administration. Materials. Twenty-nine immunodeficiency on treatment who agreed receive were included. Seven discontinued after first We collected data...
Background. APECED is a syndrome characterized by autoimmune polyendocrinopathy, candidiasis, and ectodermal dystrophy. The most observed clinical findings are chronic mucocutaneous hypoparathyroidism, adrenal insufficiency. Case Presentation. A three-year-old male patient was admitted with classical signs of juvenile idiopathic arthritis treated nonsteroidal anti-inflammatory drugs. During follow-up, autoimmunity, nail dystrophy, onychomycosis were observed. parents consanguineous, targeted...
Systemic autoimmune rheumatic diseases (SARDs) pose diagnostic challenges, particularly in pediatric populations, due to their diverse presentations and overlapping symptoms. This study aimed evaluate the concordance between indirect immunofluorescence (IIF) at different dilution levels (1/80 1/640) immunoblot findings for anti-centromere antibody (ACA) positivity. Additionally, clinical significance of ACA positivity its association with SARDs patients was assessed. retrospective,...
Abstract Objective; Immunoglobulin-A vasculitis (IgAV) is an inflammatory vascular disease that affects small blood vessels. This study was performed with the aim of identifying association between PTPN22+788G>A (rs33996649), TGF-β-509C>T (rs18004069), IL-1 β - 511C>T (rs16944), IL-5-746C/T (rs2069812), ACE I/D (rs4646994) gene polymorphisms and susceptibility to IgAV. Method; A total 53 IgAV patients 50 healthy controls were enrolled. PTPN22, TGF-β-, IL-1β polymorphisms,...
Abstract Background: APACED is a syndrome characterized by autoimmune polyendocrinopathy, candidiasis and ectodermal dystrophy. The most often observed clinical findings are chronic mucucutaneous candidiasis, hypoparatiroidism adrenal insufficiency. Case presentation: A three-year-old male patient admitted with classical signs of juvenile idiopathic arthritis began to be treated non-sterodial anti-inflammatory drugs. During follow-up, autoimmunity, nail dystrophy onychomycosis were observed....