Gülçin Aytaç

ORCID: 0000-0003-3821-5288
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About
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Research Areas
  • Adrenal Hormones and Disorders
  • Inflammasome and immune disorders
  • Immunodeficiency and Autoimmune Disorders
  • Myasthenia Gravis and Thymoma
  • Renal Diseases and Glomerulopathies
  • Lung Cancer Research Studies
  • Diabetes and associated disorders
  • Vasculitis and related conditions
  • Systemic Lupus Erythematosus Research
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Galectins and Cancer Biology
  • Chronic Lymphocytic Leukemia Research
  • Platelet Disorders and Treatments
  • T-cell and B-cell Immunology
  • Atherosclerosis and Cardiovascular Diseases
  • Protein Tyrosine Phosphatases
  • Autoimmune and Inflammatory Disorders Research
  • Urticaria and Related Conditions

Ege University
2020-2024

Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi
2023

Uniwersytecki Szpital Dziecięcy
2020

Introduction. Most patients with primary and secondary immunodeficiencies need regular Intravenous Immunoglobulin (IVIG) or Subcutaneous (SCIG) treatment. This study aimed to evaluate the serum IgG trough levels, frequency of mild severe infections, duration hospitalization, absence school, quality life in switching their IVIG therapy SCIG administration. Materials. Twenty-nine immunodeficiency on treatment who agreed receive were included. Seven discontinued after first We collected data...

10.23822/eurannaci.1764-1489.179 article EN European Annals of Allergy and Clinical Immunology 2020-11-13

Background. APECED is a syndrome characterized by autoimmune polyendocrinopathy, candidiasis, and ectodermal dystrophy. The most observed clinical findings are chronic mucocutaneous hypoparathyroidism, adrenal insufficiency. Case Presentation. A three-year-old male patient was admitted with classical signs of juvenile idiopathic arthritis treated nonsteroidal anti-inflammatory drugs. During follow-up, autoimmunity, nail dystrophy, onychomycosis were observed. parents consanguineous, targeted...

10.1155/2023/2363760 article EN cc-by Case Reports in Immunology 2023-04-25

Systemic autoimmune rheumatic diseases (SARDs) pose diagnostic challenges, particularly in pediatric populations, due to their diverse presentations and overlapping symptoms. This study aimed evaluate the concordance between indirect immunofluorescence (IIF) at different dilution levels (1/80 1/640) immunoblot findings for anti-centromere antibody (ACA) positivity. Additionally, clinical significance of ACA positivity its association with SARDs patients was assessed. retrospective,...

10.3390/children12010036 article EN cc-by Children 2024-12-28

Abstract Objective; Immunoglobulin-A vasculitis (IgAV) is an inflammatory vascular disease that affects small blood vessels. This study was performed with the aim of identifying association between PTPN22+788G>A (rs33996649), TGF-β-509C>T (rs18004069), IL-1 β - 511C>T (rs16944), IL-5-746C/T (rs2069812), ACE I/D (rs4646994) gene polymorphisms and susceptibility to IgAV. Method; A total 53 IgAV patients 50 healthy controls were enrolled. PTPN22, TGF-β-, IL-1β polymorphisms,...

10.21203/rs.3.rs-3205527/v1 preprint EN cc-by Research Square (Research Square) 2023-07-31

Abstract Background: APACED is a syndrome characterized by autoimmune polyendocrinopathy, candidiasis and ectodermal dystrophy. The most often observed clinical findings are chronic mucucutaneous candidiasis, hypoparatiroidism adrenal insufficiency. Case presentation: A three-year-old male patient admitted with classical signs of juvenile idiopathic arthritis began to be treated non-sterodial anti-inflammatory drugs. During follow-up, autoimmunity, nail dystrophy onychomycosis were observed....

10.21203/rs.3.rs-1473397/v1 preprint EN cc-by Research Square (Research Square) 2022-04-08
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