Emine Hafize Erdeniz
A5027376250- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Kawasaki Disease and Coronary Complications
- Respiratory viral infections research
- Diabetes and associated disorders
- COVID-19 and Mental Health
- COVID-19 Impact on Reproduction
- Inflammasome and immune disorders
- Mechanical Circulatory Support Devices
- Immunodeficiency and Autoimmune Disorders
- SARS-CoV-2 detection and testing
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 epidemiological studies
- Infant Development and Preterm Care
- interferon and immune responses
- Viral Infections and Outbreaks Research
- Bone Tumor Diagnosis and Treatments
- Immune Cell Function and Interaction
- Dermatological and COVID-19 studies
- Child Therapy and Development
- Infection Control and Ventilation
- Family and Patient Care in Intensive Care Units
- Pharmaceutical studies and practices
- Family and Disability Support Research
Ondokuz Mayıs University
2021-2024
Erzurum Regional Training and Research Hospital
2019-2024
Istanbul 29 Mayis University
2022
University of Health Sciences
2021
Samsun University
2021
Erzurum Technical University
2019
Sağlık Bilimleri Üniversitesi
2019
Bozok Universitesi
2016
S.B. Keçiören Eğitim ve Araştırma Hastanesi
2015
Recessive or dominant inborn errors of type I interferon (IFN) immunity can underlie critical COVID-19 pneumonia in unvaccinated adults. The risk children, which is much lower than adults, remains unexplained. In an international cohort 112 children (<16 yr old) hospitalized for pneumonia, we report 12 (10.7%) aged 1.5–13 with (7 children), severe (3), and moderate (2) 4 the 15 known clinically recessive biochemically complete IFN immunity: X-linked TLR7 deficiency children) autosomal...
We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19 pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-α2 in 10 patients: IFN-α2 only three, plus IFN-ω five, and IFN-α2, IFN-β two; nine patients). Seven (3.8%) Abs at least ng/ml one IFN, whereas the other 12 (6.6%) 100 pg/ml. The auto-Abs neutralized both unglycosylated glycosylated IFNs. also detected pg/ml 4 2,267 uninfected (0.2%) 45 (2%). odds ratios (ORs) life-threatening were, therefore,...
Human cells homozygous for rare loss-of-expression (LOE) TYK2 alleles have impaired, but not abolished, cellular responses to IFN-α/β (underlying viral diseases in the patients) and IL-12 IL-23 mycobacterial diseases). Cells common P1104A allele selectively impaired isolated disease). We report three new forms of deficiency six patients from five families (R864C, G996R, G634E, or G1010D) compound heterozygous a (A928V). All these missense encode detectable proteins. The R864C G1010D are...
Objectives: The aim of this study is to identify the epidemiological, clinical, and laboratory features coronavirus disease 2019 (COVID-19) in children. Methods: A retrospective was conducted by pediatric infectious specialists from 32 different hospitals all over Turkey case record forms. Pediatric cases who were diagnosed as COVID-19 between March 16, 2020, June 15, 2020 included. Case characteristics including age, sex, dates onset diagnosis, family, contact information recorded. Clinical...
Aim Multisystem inflammatory syndrome in children (MIS‐C) may cause shock and even death children. The aim of this study is to describe the clinical features, laboratory characteristics outcome diagnosed with MIS‐C 25 different hospitals Turkey. Methods retrospective was conducted between 8 April 28 October 2020 from 17 cities. Data were collected patients' medical records using a standardised form. Clinical outcomes according age groups, gender body mass index percentiles compared...
Tularemia is one of the most prevalent zoonoses across world. Patients in Turkiye mostly contract oropharyngeal form, acquired through drinking, or contact with microorganism-contaminated water.
The studies on children with COVID-19 are very limited. aim of this study is to reveal the effect serum 25-hydroxy vitamin D level clinical and laboratory parameters.The included 74 (35 boys 39 girls) diagnosed COVID-19. retrospective data were obtained from file records patients. Seventy-four patients divided into 3 groups (group 1, deficient; group 2, insufficient; 3, sufficient) according their levels.The mean age all was 113.25 ± 64.55 months. leucocyte count substantially higher in...
Health care workers (HCWs) are disproportionately exposed to infectious diseases and play a role in nosocomial transmission, making them key demographic for vaccination. HCW vaccination rates not optimal many countries; hence, compulsory policies have been implemented some countries. Although these effective necessary under certain conditions, resolving HCWs' hesitancies misconceptions about vaccines is crucial. HCWs the advantage of direct contact with patients; they can respond safety...
To determine the healthcare satisfaction of parents staying in hospital with their children diagnosed Covid-19 towards family-centered care and to relationship between them. This was a descriptive, correlational cross-sectional type study. Data were collected pediatric outpatient clinic university March-June 2021. The universe study consisted 141 parents, calculated sample size 59. completed 64 parents. light literature by using Sociodemographic Information Form, Family-Centered Care Scale...
Objective: Multisystem Inflammatory Syndrome in Children (MIS-C) is a disease developed after about eight weeks of the new coronavirus (COVID-19) infection children. The underlying reason for MIS-C still unknown. This study aims to assess nasopharyngeal expressions Angiotensin-converting enzyme 2 (ACE2), differentiation 147 receptor cluster (CD147), and transmembrane serine protease (TMPRSS2) receptors population. Since these are related COVID-19 infection, children with previous history...
Multisystem inflammatory syndrome in children (MIS-C) is a rare condition following SARS-CoV-2 infection associated with intestinal manifestations. Genetic predisposition, including inborn errors of the OAS-RNAseL pathway, has been reported. We sequenced 154 MIS-C patients and utilized novel statistical framework gene burden analysis, "burdenMC," which identified an enrichment for predicted-deleterious variants BTNL8 (OR = 4.2, 95% CI: 3.5-5.3, P < 10-6). encodes epithelial regulator Vγ4+γδ...
An eight-year old boy who was healthy previously had a history of use trimethoprime-sulphametoxsazole (TPM-SMX) because diarrhea ten days before presentation. He hospitalized painful swelling occured in the legs under this treatment, he fever and joint pain for last five days. In his personal history, there no pathology except frequent aphtous ulcers mouth it learned that familial any hereditary or rheumatic disease.
Introduction This report provides insight into three distinct pediatric cases exhibiting a nexus between multisystem inflammatory syndrome in children (MIS-C) and thrombotic microangiopathy (TMA) triggered by COVID-19. The aim is to underscore the range of clinical presentations essentiality early interventions. Case presents aged 10 months, 7 years, 3 years with persistent fever, diarrhea, nausea, vomiting. first case, 10-month-old girl, demonstrated acute kidney injury (AKI)...
Uygunsuz antibiyotik kullanımı ilaç yan etkisi,
Objective: In the early stages of any epidemic caused by new emerging pathogens healthcare personnel is subject to a great risk. Pandemic SARS-CoV-2, proved be no exception. Many workers died in pandemic due inadequate precautions and insufficient protection. It essential protect maintain safety for confinement as well continuity qualified services which already under strain. Educating on appropiate use personal protective equipment (PPE) procuring them. Material Methods: A survey conducted...
Objective: In the early stages of any epidemic caused by new emerging pathogens healthcare personnel is subject to a great risk. Pandemic SARS-CoV-2, proved be no exception. Many workers died in pandemic due inadequate precautions and insufficient protection. It essential protect maintain safety for confinement as well continuity qualified services which already under strain. Educating on appropiate use personal protective equipment (PPE) procuring them. Material Methods: A survey conducted...
Since December 2019, 2019 outbreak of coronavirus (Covid-19) spread all over the world as well in Turkey. In this study, we aimed to investigate clinical and laboratory effects covid 19 disease on children. The epidemiological, laboratory, radiological, treatment features 30 pediatric patients with covid-19 evaluated retrospectively. median age was 10 years, boys girls ratio 1.5 (18/12). Of patients, 80.7% had family contact 11.5% comorbidity. most common symptom fever (84.6%), cough second...