Mehmet Burhan Oflaz

ORCID: 0000-0003-1515-4654
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About
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Research Areas
  • Congenital Heart Disease Studies
  • Cardiovascular Function and Risk Factors
  • Streptococcal Infections and Treatments
  • Tracheal and airway disorders
  • Cardiac Arrhythmias and Treatments
  • Coronary Artery Anomalies
  • Aortic Disease and Treatment Approaches
  • Cardiovascular and Diving-Related Complications
  • Viral Infections and Vectors
  • Cardiovascular Issues in Pregnancy
  • Pulmonary Hypertension Research and Treatments
  • Cardiovascular Syncope and Autonomic Disorders
  • Kawasaki Disease and Coronary Complications
  • Inflammasome and immune disorders
  • Vascular anomalies and interventions
  • Connective tissue disorders research
  • Cardiac Valve Diseases and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular Disease and Adiposity
  • Viral Infections and Outbreaks Research
  • Protein Tyrosine Phosphatases
  • Poisoning and overdose treatments
  • Atrial Fibrillation Management and Outcomes
  • Urological Disorders and Treatments
  • Pericarditis and Cardiac Tamponade

Necmettin Erbakan University
2015-2024

Sivas Cumhuriyet Üniversitesi
2012-2021

Izmir Tepecik Eğitim ve Araştırma Hastanesi
2019

Yeditepe University
2015

Seoul National University Hospital
2013

Azienda Ospedaliero Universitaria San Giovanni Battista
2013

University of Turin
2013

Sivas State Hospital
2013

Türkiye Yüksek İhtisas Hastanesi
2009-2013

Van Yüzüncü Yıl Üniversitesi
2012

Objectives The aims of this study were to evaluate the prevalence, complications, and mortality hypernatremic dehydration in neonates compare effect correction rate at 48 hours on neurological outcome short term. Methods This retrospective was conducted between January 2007 2011 neonatal intensive care unit. Term included. patients grouped as follows: group 1 = 150 160 mmol/L, 2 161 170 mmol/L 3 171 189 mmol/L. Results Among 4280 neonates, 81 cases (1.8%) had dehydration. Groups 1, 2,...

10.1097/pec.0b013e3182983bac article EN Pediatric Emergency Care 2013-07-01

Aim Multisystem inflammatory syndrome in children (MIS‐C) may cause shock and even death children. The aim of this study is to describe the clinical features, laboratory characteristics outcome diagnosed with MIS‐C 25 different hospitals Turkey. Methods retrospective was conducted between 8 April 28 October 2020 from 17 cities. Data were collected patients' medical records using a standardised form. Clinical outcomes according age groups, gender body mass index percentiles compared...

10.1111/jpc.15913 article EN Journal of Paediatrics and Child Health 2022-02-24

Occlutech Figulla ASD Occluder (FSO) is an alternative device to Amplatzer Septal (ASO) with some structural innovations including increased flexibility, minimizing the amount of material implanted, and absence left atrial clamp. We aimed report our experiences FSO compare outcomes this novel versus ASO.Between December 2005 February 2009, 75 patients diagnosed secundum septal defects underwent transcatheter closure. The was used in 33 patients, ASO 42.Patient characteristics, stretch size...

10.1111/j.1540-8183.2009.00497.x article EN Journal of Interventional Cardiology 2009-09-04

Neonatal thrombocytopenia is one of the most common hematologic disorders in neonatal intensive care units (NICUs). The purpose this study was to determine prevalence and whether has an effect on occurrence intraventricular hemorrhage (IVH) ≥ grade 2 mortality rate. This carried out retrospectively neonates admitted NICU Cumhuriyet University Sivas, Turkey, between 2009 2012. Among 2218 evaluated, 208 (9.4%) developed thrombocytopenia. IVH more infants with (7.2%) than those without (4.4%),...

10.3109/08880018.2012.725454 article EN Pediatric Hematology and Oncology 2012-09-26

Impaired subclinical ventricular function may contribute to the risk of cardiovascular disease in obesity.The aim this study was determine influence obesity on left (LV) longitudinal myocardial normotensive obese children using two-dimensional (2D) speckle tracking echocardiography (STE).Case-control study.Sixty aged 10-16 years (mean age, 13.9±2.3 years) were compared with 50 normal-weight controls. Obese participants had a body mass index (BMI)≥95(th) percentile. Regional strain/strain...

10.5152/balkanmedj.2015.15136 article EN cc-by-nc-nd Balkan Medical Journal 2015-02-16

There are increasing reports about the potential role of kynurenine pathway metabolites in autism spectrum disorder (ASD). Early childhood is a very crucial period time for etiopathogenesis ASD and previous studies reported an age-dependent alteration metabolism. However, no study specifically examined young children with ASD. This aimed to investigate metabolite levels, enzyme activities neuroprotective index (kynurenic acid/3-hydroxykynurenine ratio) toddlers preschool ASD.A total 68 44...

10.1080/00207454.2020.1841187 article EN International Journal of Neuroscience 2020-10-22

Primary systemic carnitine deficiency is caused by homozygous or compound heterozygous mutation in the SLC22A5 gene on chromosome 5q31. The most common presentations are infancy and early childhood with either metabolic decompensation cardiac myopathic manifestations. We report a case of 9-year-old boy dysmorphic appearance hypertrophic cardiomyopathy. Tandem MS spectrometry analysis was compatible uptake defect (CUD). His sister had died due to sudden infant death at 19 months. second...

10.1155/2015/259627 article EN cc-by Case Reports in Genetics 2015-01-01

The aim of the study is to discuss clinical effects, treatments, and outcomes pediatric colchicine poisoning.This was designed as an observational case series study. medical records children aged between 0 18 years, who were hospitalized for poisoning at Department Pediatric Intensive Care Unit, Cumhuriyet University Faculty Medicine, January 2010 2012, retrospectively evaluated.We presented 17 with poisoning. mean (SD, range) age patients 71.5 (69.19, 18-204) months. period apply hospital...

10.1097/pec.0000000000000728 article EN Pediatric Emergency Care 2016-03-01

Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic viral disease with high mortality rate. In clinical practice, we observed bradycardia in some pediatric patients CCHF during the course. So aimed to report cases that presented course and relation of findings ribavirin therapy.Charts all hospitalized were reviewed respect age, sex, history tick bite or removing tick, other risk factors for transmission, interval between onset symptoms. Outcomes laboratory medications recorded each patient....

10.1089/vbz.2012.1200 article EN Vector-Borne and Zoonotic Diseases 2013-10-09

Background: Apoptosis is a main regulator in responses of cellular immunity throughout systemic viral infections. Perforin, soluble Fas ligand, caspase-3 and caspase-cleaved cytokeratin-18 (M-30) are mediators apoptosis. The aim this study the evaluation Crimean-Congo hemorrhagic fever (CCHF) disease changes levels these apoptotic markers relation with severity. Methods: Forty-nine hospitalized children CCHF 36 healthy controls were enrolled prospective study. patients classified into 2...

10.1097/inf.0000000000000530 article EN The Pediatric Infectious Disease Journal 2014-08-29

The anatomic changes of the patent ductus arteriosus (PDA) in adult patients can complicate its transcatheter occlusion. aim study was to determine procedural approaches facilitate closure PDA using Amplatzer duct occluder (ADO).In this prospective study, 33 consecutive with a moderate large-sized underwent closure. Conventional antegrade approach used 14 patients, while retrograde wire-guided assisted remaining 18 access antegrade. If initial procedure failed, snare-assisted technique pass...

10.5152/akd.2011.001 article EN Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology 2010-12-03

The aim of present study was (a) to evaluate the relationship between neutrophil/lymphocyte (N/L) ratio and mutation types familial Mediterranean fever (FMF) in children (b) N/L age.Three hundred forty-three with attack-free period 283 healthy control were included study. Patients divided into subgroups according types. Neutrophil lymphocyte counts retrieved from medical records patients calculated these parameters.The found be significantly higher than that controls (p<0.001). Among 343...

10.5152/eurjrheumatol.2015.0093 article EN cc-by-nc European Journal of Rheumatology 2015-03-09

We aimed to assess the association between serum levels of soluble IL-2 receptor (sIL-2r) and endothelin-1 severe infection in children with Crimean-Congo hemorrhagic fever (CCHF). Fifty-two patients under 18 years age a laboratory- confirmed diagnosis CCHF 38 healthy controls were enrolled study. Patients classified into two groups based on disease severity (severe group non-severe group). The sIL-2r observed be significantly higher compared those control (p < 0.05). In addition, also found...

10.1111/apm.12209 article EN Apmis 2013-12-10

Amplatzer septal occluder (ASO) is the most widely used device for closure of atrial defect (ASD). Figulla (FSO) a similar to ASO with some structural innovations. The aim study assess maximum P-wave duration (Pmax) and dispersion (Pd) in patients who underwent ASD both devices, determine effects innovations on electrical inhomogeneity.The retrospective cohort analysis. Between December 2005 March 2010, 121 percutaneous secundum were included this study. FSO was 79 patients, 42 patients....

10.5152/akd.2012.069 article EN cc-by-nc Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology 2012-03-01

Proinflammatory and anti-inflammatory cytokines have an important role in the pathogenesis of febrile seizures (FS). Adipocytokines like interleukin 6 (IL-6), leptin, adiponectin released from adipose tissue play a inflammation. This study aimed to assess probable children with FS. We measured serum IL-6, levels evaluated clinical laboratory findings FS (n = 32) compared results values same age illness without (febrile control, FC; n 26) healthy control group (HC; 29). The white blood cells,...

10.1177/0960327114561662 article EN Human & Experimental Toxicology 2014-12-09

We aimed to assess the association between resting heart rate (RHR) and severe infection in children with Crimean-Congo hemorrhagic fever (CCHF).In all, 121 patients under 18 years of age a laboratory-confirmed diagnosis CCHF were enrolled study. Patients classified into two groups based on disease severity (severe group nonsevere group). RHR was measured by electrocardiography (ECG) admission. Maximum P-wave duration (Pmax), dispersion (Pd), QRS duration, corrected QT interval, also...

10.1089/vbz.2013.1384 article EN Vector-Borne and Zoonotic Diseases 2013-12-20
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