Sevim Şahin

ORCID: 0000-0001-5415-5874
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About
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Research Areas
  • Epilepsy research and treatment
  • Pharmacological Effects and Toxicity Studies
  • Multiple Sclerosis Research Studies
  • Neurological and metabolic disorders
  • Metabolism and Genetic Disorders
  • Neurogenetic and Muscular Disorders Research
  • Mitochondrial Function and Pathology
  • Ophthalmology and Eye Disorders
  • Bladder and Urothelial Cancer Treatments
  • Cerebral Venous Sinus Thrombosis
  • Connective tissue disorders research
  • Neonatal and fetal brain pathology
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Infectious Diseases and Tuberculosis
  • Genetics and Neurodevelopmental Disorders
  • Toxin Mechanisms and Immunotoxins
  • Bacterial Infections and Vaccines
  • Attention Deficit Hyperactivity Disorder
  • Traumatic Brain Injury Research
  • Family and Disability Support Research
  • Cancer, Lipids, and Metabolism
  • Nutritional Studies and Diet
  • Electrolyte and hormonal disorders
  • Neuroscience and Neuropharmacology Research
  • Infectious Encephalopathies and Encephalitis

Karadeniz Technical University
2015-2024

Mardin Artuklu University
2024

Istinye University
2024

Ege Üniversitesi Tıp Fakültesi Hastanesi
2018

Schön Klinik Nürnberg Fürth
2014

Istanbul University
2010

Istanbul University-Cerrahpaşa
2010

ABSTRACT Aim : The purpose of this study was to compare HMGB‐1, TLR4, IL‐1β, IL‐1R1, and TNF‐α levels in patients with mild severe epilepsy those a healthy control group. Methods Children aged 4–17 years, diagnosed for at least three years no progressive neurological disease, metabolic disease or infection, were selected the study. group consisted 28 children one episode week despite receiving more antiepileptic drugs. 29 seizures previous year, only drug, while 27 as IL‐1β investigated...

10.1684/epd.2020.1155 article EN Epileptic Disorders 2020-04-01

ÖZET Amaç: Epilepsili hastalarda kullanılan nöbet önleyici ilaçların lökopeni ve nötropeni gibi yan etkileri yakından bilinmekle birlikte, lökosit alt tipleri üzerine iyi bilinmemektedir. Lökosit tiplerindeki değişiklikler, vücudun enflamasyon durumunu değerlendirmek için de kullanılmaktadır. Nötrofilin lenfosite oranı (NLR), bu amaçla son yıllarda yaygın indekslerdendir. Bu çalışma, bilinen ilaçlardan valproat ( VPA) karbamazepinin (KBZ) monoterapisinin NLR etkinin serum ilaç düzeyleriyle...

10.30733/std.2025.01806 article TR Selçuk tıp dergisi/Selçuk Üniversitesi Tıp Fakültesi dergisi 2025-03-22

Studies show that anti-epileptic drugs increase oxidative stress. Thus, low-density lipoprotein oxidation increases and atherogenesis is induced. Paraoxonase-associated high-density protects oxidation. The effects of on paraoxonase activity has not been investigated yet. aim this study to investigate the effect activity, lipid profiles, folat, vitamin B12, homocysteine, thyroid hormones, apolipoprotein A-1, total anti-oxidant capacity, malondialdehyd, nitric oxide, oxidised lipoprotein....

10.1017/s1047951110000697 article EN Cardiology in the Young 2010-06-02

Purpose To examine the effects of COVID-19 pandemic on lifestyle, habits, and behavioral differences in children, their changing internet use habits. Methods The research was planned as a cross-sectional study involving 4892 children aged 8 to 17 years attending schools city center Trabzon, Turkey. Children’s daily living activities, social mood temperament changes, were investigated before during pandemic. In terms problematic use, addiction rates evaluated using validated Turkish-language...

10.1177/00099228211065842 article EN Clinical Pediatrics 2021-12-10

Levetiracetam (LEV) efficacy in the treatment of chorea Huntington disease, paroxysmal nonkinesigenic dyskinesia, kinesigenic choreoathetosis, and dyskinetic cerebral palsy was reported some studies. We described a case child with Sydenham treated LEV. A 7.5-year-old male patient presented chorea, orofacial speech impairment, irritability. Echocardiographic examination revealed mitral insufficiency. diagnosed after excluding other diseases causing chorea. Although his choreiform movements...

10.1097/wnf.0000000000000084 article EN Clinical Neuropharmacology 2015-07-01

The aim of the study was to determine prevalence, risk, and predisposing factors diabetic foot ulcers in adults with diabetes. This is multi-centered descriptive cross-sectional research. Data were collected between June 2022 November seven cities, including five teaching research hospitals two public hospitals. included 357 people sample selected using stratified systematic sampling. General demographic characteristics, medical history, laboratory examination results, history ulcer and/or...

10.1016/j.jtv.2024.12.003 article EN cc-by-nc-nd Journal of Tissue Viability 2024-12-09

Background Neurological involvement is common in hemolytic uremic syndrome (HUS), but each neurological symptom may be due to a variety of factors. Objective We aimed evaluate predisposing factors the symptoms HUS. Materials and Methods The 10-year follow-up data on HUS patients were retrospectively analyzed. Statistical comparisons made across subgroups based age symptoms. Results rate was 37.5%. female-to-male ratio increased with (3.8 vs. 1.37). Regarding all patients, hemoglobin levels...

10.1055/s-0037-1603643 article EN Neuropediatrics 2017-06-01

<b>Introduction:</b> Fluid intake was reported to reduce migraine attacks. This may be due its effect on hemoconcentration. Hemoconcentration manifest itself by increasing in the hemoglobin and platelet-related values. study aimed reveal hemoconcentration evaluating complete blood cell counts attack-free periods of pediatric patients with migraine. <b>Materials Methods:</b> Consecutive children (<i>n</i> = 70) tension-type headache (TTH) 65) were compared control groups. Control 1 2 60)...

10.4103/jpn.jpn_73_19 article EN Journal of Pediatric Neurosciences 2020-01-01

ÖzGiriş: Ventriküloperitoneal şant (VPŞ) enfeksiyonları, hidrosefali nedeniyle takılan erişkin ve çocuk hastalarda, morbidite mortalitenin önemli nedenlerinden biridir.Hızlı uygun tedavi edilmeyen hastalarda zeka geriliğine, nörolojik hasarlara, hatta ölüme neden olabilmektedir.Bu çalışmanın amacı VPŞ takılmış

10.5578/ced.201843 article TR Çocuk Enfeksiyon Dergisi/Journal of Pediatric Infection 2018-12-29
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