Tuncay Dağel

ORCID: 0000-0002-1281-6571
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Research Areas
  • Dialysis and Renal Disease Management
  • Diet, Metabolism, and Disease
  • Lipoproteins and Cardiovascular Health
  • Renal Diseases and Glomerulopathies
  • Chemotherapy-induced organ toxicity mitigation
  • Cardiovascular Health and Disease Prevention
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Electrolyte and hormonal disorders
  • Liver Disease Diagnosis and Treatment
  • Cerebrovascular and Carotid Artery Diseases
  • Chronic Kidney Disease and Diabetes
  • Muscle and Compartmental Disorders
  • Diet and metabolism studies
  • Intraperitoneal and Appendiceal Malignancies
  • Biomarkers in Disease Mechanisms
  • Brucella: diagnosis, epidemiology, treatment
  • Erythropoietin and Anemia Treatment
  • Venous Thromboembolism Diagnosis and Management
  • Biomedical Research and Pathophysiology
  • Diabetes Management and Research
  • Case Reports on Hematomas
  • Inflammasome and immune disorders
  • Celiac Disease Research and Management
  • Sodium Intake and Health
  • Melamine detection and toxicity

Ministry of Health
2024

Erzincan University
2023

Koç University
2017-2022

Bursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi
2015

ABSTRACT Capillary rarefaction is broadly defined as a reduction in vascular density. the kidneys thought to promote hypoxia, impair hemodynamic responses and predispose chronic kidney disease (CKD) progression hypertension development. Various mechanisms have been suggested play role development of capillary rarefaction, including inflammation, an altered endothelial-tubular epithelial cell crosstalk, relative deficiency angiogenic growth factors, loss pericytes, increased activity...

10.1093/ckj/sfx133 article EN cc-by-nc Clinical Kidney Journal 2017-11-23

In the present study, protective effects of adenosine triphosphate (ATP), Benidipine, and Lacidipine on potential kidney damage induced by 5-fluorouracil (5-FU) were investigated in rats.

10.26355/eurrev_202403_35760 article EN PubMed 2024-03-01

It is classically thought that it the amount of salt critical for driving acute blood pressure responses. However, recent studies suggest responses, at least acutely, may relate to changes in serum osmolality. Here, we test hypothesis responses can be altered by concomitant water loading. Ten healthy patients free any disease and medication underwent 4 interventions each a week apart which they took 300 mL lentil soup with no (visit 1), 3 g 2), or 500 3) 750 4). At visit, hourly measurements...

10.1111/jch.13374 article EN Journal of Clinical Hypertension 2018-09-19

Background: The consumption of sweetened beverages is associated with increased risk metabolic syndrome, cardiovascular disease, and type 2 diabetes mellitus. Objective: We hypothesized that the effects fructose in sugary might be modulated by speed ingestion addition to overall amount. Design: Thirty healthy subjects free any disease medication were recruited into two groups. After overnight fasting, group 1 drank 500 mL apple juice over an hour drinking 125 every 15 min, while 5 min. Blood...

10.3390/nu13061916 article EN Nutrients 2021-06-02

We aimed to determine whether serum SPON2 is a useful biomarker in the detection of Diabetic Nephropathy (DN) and compare levels with 24-hour urinary albumin excretion rate (UAER) patients DN at different stages.The cohort included 80 adult T2D 20 healthy controls. The were divided into four groups according UAER creatinine (sCr) levels. Group 1 consisted normoalbuminuria (n = 20), 2 microalbuminuria 3 macroalbuminuria 20) 4 albuminuria sCr > 1.5 mg/dL 20).There no significant differences...

10.1111/nep.12507 article EN Nephrology 2015-05-14

Background and aim Glycemic fluctuations around a mean glucose level, referred as glycemic variability blood pressure (BPV) are considered independent risk factors for cardiovascular diseases, all-cause mortality, disease-mortality. With this background in mind, we aimed to investigate the association between BPV their normoglycemic normotensive individuals. Materials method Twenty-seven individuals were recruited. Twenty-four hour Holter devices utilized measure ambulatory (BP) while...

10.1097/mbp.0000000000000491 article EN Blood Pressure Monitoring 2020-10-16

Objective Blood pressure variability (BPV) is considered as a novel risk factor for cardiovascular disease including left ventricular hypertrophy, vascular stiffness, and renal dysfunction. In this study, we aimed to determine the relationship between ambulatory BPV with subclinical organ damage stiffness parameters in normotensive healthy subjects. Methods A total of 100 subjects over 18 years age were included cross-sectional study. We divided participants into two groups according median...

10.1097/mbp.0000000000000430 article EN Blood Pressure Monitoring 2020-01-08

Background and Objective: Amiodarone-induced kidney damage is associated with an increase in oxidant proinflammatory cytokines.This study was planned to investigate the effect of thiamine pyrophosphate (TPP) on amiodarone-induced oxidative inflammatory rats both a biochemical histopathological basis.Materials Methods: Albino Wistar-type male (6 per group) were divided into healthy (HG), amiodarone (ADG) amiodarone+TPP (TAG) groups.The TPP (20 mg kgG 1 ) (50 treatment continued for 14...

10.3923/ijp.2023.521.530 article EN International Journal of Pharmacology 2023-04-15

Abstract Objectives In many diseases, immature platelet fraction (IPF%) is related to coagulopathy and poor outcome. This study aimed investigate the predictive value of IPF% for severity pneumonia in patients with Coronavirus Disease 2019 (COVID-19). Methods A total 154 COVID‐19 infections were included. The divided into two groups according (severe non-severe) regarding their oxygen demand. Results Given laboratory parameters, median was significantly higher severe group (11.9 vs. 3.9%,...

10.1515/tjb-2021-0070 article EN cc-by Turkish Journal of Biochemistry 2021-07-13

What is known and objective Erlotinib a small molecule tyrosine kinase inhibitor which blocks the activation of epidermal growth factor receptor (EGFR), transmembrane that upregulated in many cancer types. Inhibition angiogenesis with consequent impairments intratumoral microcirculation one mechanisms through EGFR inhibition halts progression cancer. A consequence impaired hypoxia, results increases serum uric acid levels. The goal this study was to investigate relationship between levels...

10.1111/jcpt.13071 article EN Journal of Clinical Pharmacy and Therapeutics 2019-11-28

Tuberculosis (Tbc) continues to threaten humanity. Amyloidosis is one of the most common complication Tbc. Proteinuria can be observed during clinical follow-up and it may mimic nephrotic syndrome. In this case report, a 45-year-old man who was diagnosed with cavitary Tbc detected search for etiology proteinuria presented. The symptoms regressed anti-tbc therapy. KEy wORDS: Tuberculosis, Proteinuria, doi: 10.5262/tndt.2013.1001.21 Yazisma Adresi: Bennur Esen GULLU Bursa Sevket Yilmaz Egitim...

10.5262/tndt.2013.1001.21 article TR Turkish Nephrology Dialysis Transplantation 2013-01-16

Retroperitoneal fibrozis (RPF) steroid tedavisine sıklıkla yanıt veren kronik enflamatuvar hastalıktır.Bu yazıda, anüri nedeni ile başvuran, RPF'ye bağlı bilateral hidronefrozu tespit edilen ve steroide çok hızlı bir olgu sunuldu.Altmış beş yaşında erkek hasta, üç gündür idrar yapamama yakınması başvurdu.Laboratuvar testlerinde üre: 156 mg/dl, kreatinin: 15 mg/dl idi.Karın bilgisayarlı tomografisinde (BT) retroperitenal mesafede paraaortik alanlarda yaygın yumuşak doku yoğunluk artışı...

10.5505/1304.8503.2011.03511 article TR Istanbul Medical Journal 2011-01-01

Renal onkositoma goreceli olarak bobregin nadir gorulen neoplazmadir. Literaturde cok az vakada oncesinde non-Hodgkin lenfoma (NHL) tanisi ile izlenen bir hastada renal tanimlanmistir. Bu yazida NHL izlenirken konulan hasta sunuldu. Otuz alti yasinda kadin poliklinigimize 2 gundur olan yan agrisi ve dizuri yakinmasi basvurdu. Hasta 15 yil once 8 kur kemoterapi almis, halen son 10 yildir remisyonda izleniyordu. Fiziki muayenesi normaldi. Hem ultrasonografide hem de abdominal tomografide sag...

10.5505/1304.8503.2012.72692 article TR Istanbul Medical Journal 2012-01-01
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