A5069911233- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Pharmaceutical and Antibiotic Environmental Impacts
- Plant Pathogens and Fungal Diseases
- Antifungal resistance and susceptibility
- Bacteriophages and microbial interactions
- Biosensors and Analytical Detection
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Infections and bacterial resistance
- Vibrio bacteria research studies
- Amoebic Infections and Treatments
- Enterobacteriaceae and Cronobacter Research
- Nail Diseases and Treatments
- Salmonella and Campylobacter epidemiology
- Bacillus and Francisella bacterial research
- Herpesvirus Infections and Treatments
- Fungal Infections and Studies
- Burkholderia infections and melioidosis
- Corporate Taxation and Avoidance
- Streptococcal Infections and Treatments
- Yeasts and Rust Fungi Studies
- Bacterial Infections and Vaccines
Växjö Kommun
2020-2024
Acıbadem University
2015-2019
Acıbadem Adana Hospital
2015-2018
Kent Hastanesi
2018
Istanbul University
2016
Marmara University
2010-2013
Pseudomonas aeruginosa, a ubiquitous opportunistic pathogen considered one of the paradigms antimicrobial resistance, is among main causes hospital-acquired and chronic infections associated with significant morbidity mortality. This growing threat results from extraordinary capacity P. aeruginosa to develop resistance through chromosomal mutations, increasing prevalence transferable determinants (such as carbapenemases extended-spectrum β-lactamases), global expansion epidemic lineages. The...
Introduction Standard, phenotypic antimicrobial susceptibility testing (AST) methods require 16–20 h of incubation and are considered as the bottleneck in providing timely input for appropriate treatment. In this study, a novel adenosine triphosphate (ATP)-bioluminescence-based method which allows rapid AST within 3 was described. Methods Standard performed 56 Enterobacterales isolates using EUCAST disk diffusion (DD) methodology. For bioluminescence-based AST, suspensions bacteria were...
Carbapenems are the choice of treatment in infections caused by multidrug resistant Enterobacteriaceae. In recent years carbapenem-resistant Enterobacteriaceae isolates due to carbapenemases have been increasingly reported worldwide. Multicenter studies on scarce Turkey. The aim this study was determine distribution from different parts Turkey as a part European Survey Carbapenemase Producing (EuSCAPE) project. Beginning November 2013, at least one agents, namely imipenem, meropenem, and...
Recently, new carbapenemases in Enterobacteriaceae strains and non-fermentative gram-negative bacilli have been reported. The New Delhi metallo-β-lactamase-1 (NDM-1) is a major problem around the world. purpose of this article to address NDM-1 Klebsiella pneumoniae epidemic detected eight cases our hospital.Bacteria identified were from patients already admitted intensive care unit Sakarya University Training Research Hospital during efforts toward establishment infection surveillance...
ObjectivesMelioidosis, caused by Burkholderia pseudomallei, requires intensive antimicrobial treatment. However, standardized susceptibility testing (AST) methodology based on modern principles for determining breakpoints and ascertaining performance of methods are lacking B. pseudomallei. This study aimed to establish MIC zone diameter distributions which set epidemiological cut-off (ECOFF) values pseudomallei using standard EUCAST non-fastidious organisms.MethodsNon-consecutive,...
Hepatitis C infection is a public health problem. The aim of this retrospective study was to determine the distribution hepatitis virus (HCV) genotypes in seven regions Turkey, by evaluating 7002 patients with chronic HCV six-year period. During 2009–2014 period, serum/plasma samples from new consecutive RNA positive were collected. female 3867 (55.2%). genotype patiens evaluated ages and years. Statistical analysis performed using Mann–Whitney test χ2 analysis. 1b most common (67.7%)...
In this study, the performance of "RESIST-3 O.K.N. K-SeT" (Coris BioConcept, Gembloux, Belgium) immunochromatographic assay was evaluated in 132 Klebsiella pneumoniae comprising 102 carbapenem resistant and 30 susceptible isolates. Genotypically known isolates Gram negative bacteria (n=22) including various species were also tested by as controls. The run PCR for blaKPC, blaIMP, blaVIM, blaNDM, blaOXA-48. rates blaOXA-48, blaKPC found at 52.9%, 39.2%, 2.0%, respectively. Both blaNDM...
Staphylococcus aureus is one of the first bacteria colonizing in cystic fibrosis (CF) respiratory tract and different virulence factors are responsible for disease progression. It not clear if CF S. strains more virulent than isolated from non-CF patients.Biofilm production was detected by a modified tissue culture plate method, presence genes encoding Panton-Valentine leukocidin (PVL) investigated signal amplified sandwich hybridization assay antimicrobial susceptibility patterns were disk...
Francisella tularensis is the cause of zoonotic disease tularemia and classified among highly pathogenic bacteria (HPB) due to its low infection dose potential for airborne transmission. In case HBP, there a pressing need rapid, accurate reliable identification. Phenotypic identification species inappropriate clinical microbiology laboratories because it time-consuming, hazardous subject variable interpretation. Matrix-assisted laser desorption ionization-time flight mass spectrometry...
The objective of this study was to investigate the development a surface plasmon resonance (SPR) sensor platform equipped with multiple channels for simultaneous determination methicillin-resistant
Abstract Objectives Most human infections caused by Vibrio spp. do not warrant antimicrobial treatment but in severe cases, targeted can be lifesaving. For spp., standardized susceptibility testing (AST) guidelines with EUCAST methodology are lacking. In this study, we aimed to produce data suitable for establish clinical MIC breakpoints and zone diameter correlates Methods An intercontinental collection (N = 524) comprising five important (V. alginolyticus, V. cholerae, fluvialis,...
Accurate and rapid identification of yeast isolates have become important in recent years for not only antifungal susceptibility testing due to the species-specific clinical resistance breakpoints but also early initiation appropriate therapy. In microbiology laboratories species yeasts is often performed with several commercial systems based on biochemical properties rarely according physiological morphological characteristics. The aim this study was compare two common systems, VITEK 2 YST...
There is an urgent need to be able identify carbapenemase-producing Enterobacterales. In this study we aimed compare the performance of MALDI Biotyper Selective Testing Antibiotic Resistance-βLactamase (MBT STAR-BL) test with in-house Carba NP in their ability rapidly detect carbapenemase production Escherichia coli and Klebsiella pneumoniae strains. MBT STAR-BL testing were performed parallel. One hundred sixty-nine isolates total tested. K. (n = 139) E. 14) strains previously characterized...
Amebiasis olgularının üçte birinde amip trofozoitlerinin bağırsak duvarını delip dolaşımla vücuda dağılmaları sonrası hastalarda karaciğer absesi oluşabilmektedir.Bu tabloya çoğunlukla 20-45 yaş arası erkek rastlanılmakta ve olgularda yüksek ateş sağ üst kadranda ağrı ile giden ciddi bir tablo gözlenmektedir.Amebik Karaciğer Absesi (AKA) hastalarına tanı konulduğunda ne gastrointestinal sisteme ait yakınmalara de dışkı incelemelerinde ntamoeba histolytica (E.histolytica) kist veya...
ÖZETStreptococcus pneumoniae ve Haemophilus influenzae bakteriyel alt solunum yolu infeksiyonu etkenleri arasında önde gelmeleri tedavileri için kullanılan antibiyotiklere karşı geliştirdikleri direnç nedeniyle klinik önemlerini korumaktadırlar.Ampirik tedavi seçeneklerinin belirlenmesi epidemiyolojisinin izlenmesi gerekmektedir.Çalışmamızda 2012-2014 yıllarında örneklerinden izole edilmiş S.pneumoniae (n = 223) H.influenzae 363) suşunun antimikrobiyal duyarlılıklarının değerlendirilmesi...
We evaluated the usefulness of Carba NP test for rapid detection carbapenemase activity in Bacteroides spp. The minimum inhibitory concentration (MIC) imipenem was determined with gradient strips, and cfiA gene investigated by polymerase chain reaction 27 clinical isolates. performed according to recommendations Clinical Laboratory Standards Institute. Among three harboring isolates, two resistant isolates were positive, while intermediate isolate negative. Our preliminary results suggest...
Brucellosis is a zoonotic infectious disease caused by the bacterial genus Brucella.It may affect several species of domestic and wild animals, as well humans considered one most common diseases worldwide.The organism has ability to survive in intracellular environment, contained within polymorphonuclear cells macrophages.The infection be localized or systemic soft tissue involvement rare presentations brucellosis.Brucellosis breast tissue, however quite human infections.These nonspecific...