- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Resistance in Staphylococcus
- Central Venous Catheters and Hemodialysis
- Urinary Tract Infections Management
- Bacterial biofilms and quorum sensing
- Nosocomial Infections in ICU
- Streptococcal Infections and Treatments
- Sepsis Diagnosis and Treatment
- Infections and bacterial resistance
- Enterobacteriaceae and Cronobacter Research
- Mycobacterium research and diagnosis
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Hematopoietic Stem Cell Transplantation
- Antifungal resistance and susceptibility
- Infection Control in Healthcare
- Diphtheria, Corynebacterium, and Tetanus
- Disaster Response and Management
- Infectious Disease Case Reports and Treatments
- Neonatal and Maternal Infections
- Intensive Care Unit Cognitive Disorders
- Fetal and Pediatric Neurological Disorders
Ege University
2011-2024
Trakya University
2021
Ege Üniversitesi Tıp Fakültesi Hastanesi
2015
In this study, we aimed to evaluate the epidemiology and antimicrobial resistance (AMR) patterns of bacterial pathogens in COVID-19 patients compare results with control groups from pre-pandemic pandemic era.
Abstract Background Acinetobacter spp has emerged as an important nosocomial pathogen causing life-threatening infections in hospitalized patients. Since carbapenem-resistant bloodstream have been increasingly reported the pediatric population worldwide recent years, we aimed to evaluate clinical characteristics and identify possible risk factors patients with infections. Methods We retrospectively analyzed results of blood-stream caused by spp. children between 2014-2022. Demographic...
AbstractThe increasing prevalence of resistant Gram-positive cocci requires the need to search for more effective agents and synergistic combinations. Forty-two vancomycin- Enterococcus faecium (VREF), 30 methicillin-resistant Staphylococcus aureus (MRSA) 36 epidermidis (MRSE) strains were studied. Minimum inhibitory concentrations (MICs) determined synergy testing was performed by using E test daptomycin, ampicillin-sulbactam, piperacillin-tazobactam ticarcillin-clavulanate against...
The increasing incidence of Stenotrophomonas maltophilia ( S. ) infections raises concern because the high fatality/case ratio. This study aimed to evaluate risk factors for infection and mortality associated with bloodstream (BSIs) in children compare them Pseudomonas aeruginosa BSIs.All BSIs caused by (n:73) P. (n:80) were enrolled this between January 2014 December 2021 at Medical School Ege University.Previous Pediatric Intensive Care Unit (PICU) admission, prior glycopeptide, carbapenem...
BACKGROUND: Despite the well‐known contamination rates and presence of microbial agents in stem cell products, risk factors affecting have not been well described. STUDY DESIGN AND METHODS: In a 12‐year period, we retrospectively reviewed culture results peripheral blood products with intent identifying for contamination. RESULTS: Microbial was detected 28 (5.7%) postprocessing period 18 (3.66%) postthawing period. Large‐volume leukapheresis (LVL; odds ratio [OR], 5.85; 95% confidence...
OBJECTIVE Cerebrospinal fluid (CSF) shunt infections caused by gram-negative bacteria are difficult to treat given the limited treatment options and emergence of carbapenem-resistant (CR) strains. This study aimed evaluate demographic clinical characteristics children with CSF external ventricular drain (EVD) bacteria, identify risk factors for acquiring CR infections, report on outcomes these infections. METHODS A retrospective cohort was designed pediatric patients EVD between January 2013...
The increasing prevalence of resistant Gram-positive cocci requires the need to search for more effective agents and synergistic combinations. Forty-two vancomycin- Enterococcus faecium (VREF), 30 methicillin-resistant Staphylococcus aureus (MRSA) 36 epidermidis (MRSE) strains were studied. Minimum inhibitory concentrations (MICs) determined synergy testing was performed by using E test daptomycin, ampicillin-sulbactam, piperacillin-tazobactam ticarcillin-clavulanate against staphylococci;...
Two new zinc phthalocyanine derivatives bearing four 3,5-di-tert-butyl-4-hydroxyphenyl (ZnPc1) and 3,5-dimethylphenoxy (ZnPc2) have been synthesized proved by elemental analyses UV-vis, 1 H NMR, FTIR MALDI-TOF mass spectra as spectroscopic determination. Thermal stabilities of these neutral Zn -phthalocyanines were performed thermal gravimetric analysis and, significantly, found stable up to 373 °C for ZnPc1 550 ZnPc2. In addition, the photostability sensitizers was quite successful within...
The aim of this study was to evaluate the performance EVIGENE VRE Detection kit and compare it with PCR, considered gold standard for detection vancomycin-resistant enterococci (VRE). correlation between MIC values vancomycin teicoplanin using epsilon test also determined. In kit, DNA probes specific bacterial target sequences are bound microwell plates. A hundred ten (104 Enterococcus faecium six faecalis ) 45 vancomycin-susceptible E. were tested. All strains found be positive vanA...
Giriş: Hastane kökenli ya da sağlık bakımı ile ilişkili enfeksiyonların (HE) görülme sıklığı ülkeden ülkeye, hatta aynı hastanenin farklı birimlerine göre değişebilmektedir
Objective: In this study, it was aimed to investigate in vitro activities of linezolid combined with vancomycin, teicoplanin, fusidic acid, and ciprofloxacin against Gram-positive pathogens. Material Methods: This study conducted at Ege University, Faculty Pharmacy, Department Pharmaceutical Microbiology. Clinical isolates used were obtained retrospectively from the collection University Medical Faculty, Microbiology Microbiology, Bacteriology Laboratory. Minimal inhibitor concentrations...
Amaç: Bu çalışmanın amacı, 2014 ve 2018 yılları arasında yoğun bakım ünitelerinde (YBÜ) sağlık çalışanlarının el hijyeni uyum oranını saptamaktır. Gereç Yöntem: araştırma yedi YBÜ’de (Çocuk Sağlığı Hastalıkları, Yenidoğan, İç Anestezi Reanimasyon, Göğüs Nöroloji Kalp Damar Cerrahisi) çalışan doktor, hemşire yardımcı personelinin uyumunu değerlendiren prospektif, gözlemsel bir çalışmadır. El uyumu enfeksiyon kontrol hemşireleri tarafından Dünya Sağlık Örgütü (DSÖ) beş endikasyonuna göre Ocak...
Abstract Purpose: In this study, we aimed to evaluate the epidemiology and antimicrobial resistance (AMR) patterns of bacterial pathogens in COVID-19 patients compare results with control groups from pre-pandemic pandemic era. Methods: Microbiological database records all diagnosed Ege University Hospital between March 15, 2020, June evaluated retrospectively. Patients who acquired secondary infections (SBIs) co-infections were analyzed. Etiology AMR data collected. Results also compared era...
Aim: During the COVID-19 pandemic, a large number of intensive care unit beds have been organized for critically ill patients. However, need non-COVID-19 critical patients continues. In our study, we aimed to compare admitted internal medicine from emergency department before and during pandemic period.
 Materials Methods: Patients who were grouped as pre-pandemic (March 2018-March 2020) 2020-March 2022) compared retrospectively in terms hospitalisations, demographic characteristics,...
Amaç: Sağlık bakımı ile ilişkili enfeksiyonların önlenmesinde el yıkama, çevre temizliği, izolasyon kurallarına uyum gibi temel uygulamalar birlikte Enfeksiyon kontrol komitesinin yürüttüğü aktif sürveyans ve personel eğitimi büyük önem taşımaktadır. Bu çalışmada karbapenem dirençli Enterobacteriaceae (KDE) salgın yönetim tecrübesinin aktarılması yapılan uygulamaların değerlendirilmesi amaçlanmıştır. Gereç Yöntem: Organ Nakli Servis’inde 22.05.20 14.06.20 tarihleri arasında yatan tüm...
Abstract Background The increasing prevalence of carbapenem-resistant Enterobacteriaceae (CRE) infections among children represents a significant global concern, leading to elevated mortality rates. aim this study was evaluate the risk factors, outcomes, 30-day rates and contributing factors in with CRE bloodstream (CRE-BSIs). Methods Data regarding demographic characteristics, treatment approaches outcomes hospitalized aged 0–18 years diagnosed CRE-BSIs between January 2018 December 2022...