Abstract Purpose To investigate the incidence and risk factors of retinal detachment (RD) bacterial endophthalmitis in a cohort children who underwent cataract surgery before age eight. Methods Data was retrieved from Swedish national paediatric register. All eyes with congenital or infantile that between January 1, 2007, December 31, 2023 at least one follow‐up were included. Cases associated trauma, uveitis RD excluded. Parameters could be important for complications analysed. Results...

Thiosemicarbazides (2a–e) were obtained by the interaction of pyridine-4-carboxylic acid hydrazide (1) with five different isothiocyanate (RNCS) derivatives. By addition KOH to reaction medium, ethyl, allyl, phenyl and benzyl, p-tolyl substituted 1,2,4-triazoles (3a–e) obtained. 3a–e dissolved in dry acetone containing K2CO3 presence 2-chloro-1-(3-methyl-3- mesitylcyclobutyl) ethanone (4) give 3,4,5-trisubstituted 1,2,4-triazole sulfanyl compounds a cyclobutane ring (5a–e). The structures...

To determine the demographic and ocular features affecting contrast sensitivity levels in healthy individuals.Seventy-four eyes of 37 subjects (7-65 years old) with refractive errors less than 1.0 diopter, no history surgery, 20/20 visual acuity were included study. The participants divided by age into three groups: group 1, 7-19 years, n=11; 2, 20-49 n=15; 3, 50-65 n=11. All underwent anterior posterior segment evaluation, intraocular pressure measurements, refraction clinical evaluation...

To compare and evaluate the phacoemulsification parameters postoperative endothelial cell changes of two different machines, each with modes, but also to assess relationship between loss parameters, as well other factors in both groups.This prospective observational study was comprised consecutive eligible cataract patients operated technique performed by same surgeon using either a WHITESTAR Signature Ellips FX (transversal, group 1) or Infiniti OZil IP (torsional, 2) machine.The included...

To investigate subfoveal choroidal thickness (SFCT) in patients with pre-eclampsia using enhanced depth imaging optical coherence tomography (EDI-OCT).A sample of 73 pregnant women was studied over 28 weeks gestation. The divided into two groups: one comprising pre-eclamptic (n=32), and the other healthy (n=41). SFCT determined for all EDI-OCT during pregnancy at third month postpartum period.The SFCTs were 351.97 ± 22.44 332.28 20.32 µm periods (p<0.001), respectively, whereas these values...

Purpose: To obtain aqueous humor and tear fluid samples during cataract surgery of the hepatitis C virus (HCV)-antibody-positive patients in order to analyze them for HCV RNA compare these measurements with serum levels.Methods: Twenty-nine anti-HCV-positive were included this study. viral load levels determined by commercial real-time polymerase chain reaction system. Antibodies screened enzyme-linked immunosorbent assay (ELISA) using anti-HCV test kit.Results: Log10 found be 6.00 ± 1.06...

Abstract 1,2,4‐Triazoles are used as antifungal, antibacterial, antimicrobial, and antioxidant against some oxidative radical species. Recently, many 1,2,4‐triazoles continue to be synthesized. In this study, the effect of 1,2,4‐triazole derivatives on human colon cancer (HT29) was investigated in vitro vivo rats. MTT test applied experiments. For rats were divided into seven groups follows: Control group (negative control), azoxymethane (AOM), AOM + cisplatin 15, L1, L2, L3, L4. To create...

Purpose: The purpose of this experiment was to investigate the possible toxic effects Nepafenac, a nonsteroidal anti-inflammatory molecule, after its intravitreal application in various concentrations. Methods: Forty pigmented rabbits were randomly divided into 4 groups, each including 10 rabbits. active ingredient Nepafenac prepared be applied different doses, for use. Under topical anesthesia, following pupil dilatation, 0.3, 0.5, 0.75, and 1.5 mg doses intravitreally right eye. In rabbit,...

The aim of this study was to investigate the effect Valsalva maneuver on corneal morphology and anterior chamber parameters in patients with keratoconus.A total 39 eyes from keratoconus 41 age-matched gender-matched healthy individuals were included cross-sectional study. Measurements front keratometry values (K-flat, K-steep, K-max), central thickness, apex thinnest volume, volume (ACV), depth (ACD), iridocorneal angle (ICA) performed a Pentacam Scheimpflug camera (Oculus, Germany) before...

There are many etiological factors that have led to the development of retinal pigment epithelial detachment (PED). In this paper, we reported a patient with isolated multiple PEDs. Based on fact, paper aimed give an overview causes

To determine the qualitative and quantitative vitreoretinal interface characteristics with spectral domain optical coherence tomography (SD-OCT) in eyes macular hole (MH) investigate their relation best corrected visual acuity (BCVA) MH duration.Sixty-one of 46 consecutive patients diagnosed idiopathic were included study. The mean age was 66.7±7.5 (51-79) years. Complete ophthalmologic examination SD-OCT performed all stages determined according to findings. Qualitative investigated,...

Purpose: We aimed to evaluate the differences in corneas of eyes with isolated iris coloboma.Methods: This study was designed as a prospective study. Among patients who applied our hospital within last 3-year period, those coloboma one eye and completely normal contralateral were included In addition complete ophthalmologic examination, all scanned by Pentacam Scheimpflug camera dark, corneal endothelium cell count taken using Topcon Specular Microscope. Data entered SPSS software then...

There is an urgent need for a drug to be used against COVID-19, which negatively affects human life worldwide and causes pandemic leading the death of many people. Although some drugs are included in treatment protocols health institutions, there currently no specific COVID-19 or unknown, effective options remain very limited. Since designing novel testing its pharmacological properties may take long years, here we faster virtual study approach our compounds with different chemical...

Objective . We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods The study included 20 cases with POAG (group 1, mean age<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mn>58.68</mml:mn><mml:mo>±</mml:mo><mml:mn>13.3</mml:mn></mml:math>years) 30 healthy individuals 2, id="M2"><mml:mn>58.68</mml:mn><mml:mo>±</mml:mo><mml:mn>13.6</mml:mn></mml:math>years). In all cases,...

Objectives: The aim of this study was to compare the thickness each corneal sublayer in patients with mitral valve prolapse (MVP) and healthy individuals. Methods: A total 38 eyes from MVP 34 age- sex-matched individuals were included study. epithelium, Bowman layer, stroma, Descemet membrane—endothelium complex measured on central cornea (i.e., apex) both inferior superior halves anterior segment module spectral domain optical coherence tomography. Results: No statistically significant...

In this study, the cytotoxic effects of some 2- (4H- [1,2,4] triazol-3-yl-sulfanyl)-acetamide derivatives compounds on L1210 rodent leukemia cancer cell line were investigated. At same time, effect MDA concentration showing degree lipid peroxidation in Saccharomyces cerevisiae yeast cells treated with these and vitamin A, E C values addition, antioxidant properties investigated by DPPH radical scavenging method. It was determined that did not make a statistically significant difference E,...

In this research, the effect of thiophene derivatives on (MDA) concentration which is an indicator lipid peroxidation, antioxidant vitamins A, E and in vitro activity antitumor activity, were investigated cell culture media. comparison done among groups, it was observed that MDA vitamin A concentrations statistically (P&lt;0.05) changed. Looking at measured parameters during experiment, number live cells, compounds effective L 1210 types. The oxidative stress are used for all compounds.