A5085667324- Glycosylation and Glycoproteins Research
- Microbial bioremediation and biosurfactants
- Invertebrate Immune Response Mechanisms
- Pancreatic function and diabetes
- Infant Nutrition and Health
- Metabolism and Genetic Disorders
- Neurobiology and Insect Physiology Research
- Blood groups and transfusion
- Silk-based biomaterials and applications
- Mass Spectrometry Techniques and Applications
- Aquaculture disease management and microbiota
- Silkworms and Sericulture Research
- Anaerobic Digestion and Biogas Production
- Seaweed-derived Bioactive Compounds
- Effects and risks of endocrine disrupting chemicals
- Skin and Cellular Biology Research
- Inflammatory mediators and NSAID effects
- Retinal Diseases and Treatments
- Carbohydrate Chemistry and Synthesis
- Respiratory and Cough-Related Research
- Marine Toxins and Detection Methods
- Digestive system and related health
- Advanced Cellulose Research Studies
- Echinoderm biology and ecology
- RNA Research and Splicing
Ege University
2013-2023
Manisa Celal Bayar University
2022
SUMMARY Sialic acid is a terminal sugar of carbohydrate chains that participates in numerous biological events. Recent studies have explored the mechanism carbohydrate‐mediated fertilisation to understand biochemistry fertilisation, although type and quantity sialic role during remain unknown. Echinoderm particular has been studied extensively, yet our understanding mechanisms remains incomplete. In this study, we characterised types egg jelly coat sea urchin, Paracentrotus lividus , using...
Biodegradation is a cost-effective process commonly used to eliminate many xenobiotic hydrocarbons such as diesel oils. However, their hydrophobic character reduces the biodegradation efficiency. In order overcome this hurdle, kurstakins isolated from Bacillus thuringiensis strain 7SA were emulsifying agents. The influence of kurstakin molecules on oil degradation by Acinetobacter haemolyticus 2SA was evaluated in presence and absence aforementioned lipopeptide. rates gene expressions alkane...
Sea urchin eggs are surrounded by a carbohydrate-rich layer, termed the jelly coat, that consists of polysaccharides and glycoproteins. In present study, we describe two mass spectrometric strategies to characterize N-glycosylation Paracentrotus lividus egg which has an alecithal-type extracellular matrix like mammalian eggs. Egg was isolated, lyophilized, dialyzed, followed peptide N-glycosidase F (PNGase-F) treatment release N-glycans from their protein chain. These were then derivatized...
Purpose: The purpose of this experiment was to investigate the possible toxic effects Nepafenac, a nonsteroidal anti-inflammatory molecule, after its intravitreal application in various concentrations. Methods: Forty pigmented rabbits were randomly divided into 4 groups, each including 10 rabbits. active ingredient Nepafenac prepared be applied different doses, for use. Under topical anesthesia, following pupil dilatation, 0.3, 0.5, 0.75, and 1.5 mg doses intravitreally right eye. In rabbit,...
Sialic acids mainly occur as components on cell surface glycoproteins and glycolipids. They play a major role in the chemical biological diversity of glycoconjugates. Although sialic exhibit great structural variability vertebrates, glycoconjugates with have also been determined small amounts invertebrates. It has suggested that important roles development function nervous system. Despite Bombyx mori being model organism for investigation many physiological processes, acid changes its system...
The implementation of nanotechnology in pulmonary delivery systems might result better and more specific therapy. Therefore, a nano-sized drug carrier should be toxicologically inert not induce adverse effects. We aimed to investigate the responses polymer nano carrier, lysine poly-hydroxyethyl methacrylate nanoparticle (NP) [Lys-p(HEMA)], loaded with formoterol, both vitro vivo an ovalbumin (OVA) asthma model. successfully synthesized nanodrug formulation showed expectedly steady release...
Abstract Background Cytidine monophospho-n-acetylneuraminic acid hydroxylase ( CMAH ) gene associated with blood groups in cats encodes enzyme that converts Neu5Ac to Neu5Gc. Although variations of pedigree have been revealed, the presence/lack them non-pedigree stray is unknown. Therefore, present study aimed investigate and quantity Neu5Gc on erythrocytes (n:12) living İzmir, Turkey. Also, frequency types was determined 76 including 12 were used for Neu5A/Neu5Gc analysis. Results In total,...
Abstract Cytidine monophospho-n-acetylneuraminic acid hydroxylase ( CMAH ) gene associated with blood groups in cats encodes enzyme that converts Neu5Ac to Neu5Gc. Although variations of pedigree have been revealed, the presence/lack them non-pedigree stray is unknown. Therefore, present study aimed investigate and quantity Neu5Gc on erythrocytes (n:12) living İzmir, Turkey. Meanwhile, these 12 were typed using mitochondrial DNA control region. Also, frequency types was determined 76...
Nicotine, is an alkaloid compound consisting of pyridine and pyrolidine ring. Its closed formula C10H4N2. During smoking peak plasma concentration changes from 25 to 50 ng/mL. half-life 1–2 h. Nicotine metabolized primarily in the liver excreted by kidneys. The nicotine metabolite cotinine 10 times more than its longer around 15 20 Cotinine can be found both amniotic fluid umbilical cord blood given that it passes across placental barrier. Adverse effects metabolites on fetus are suggested...
Glycans are expressed as conjugates of glycoproteins, glycolipids, and proteoglycans. The huge diversity glycans on glycoconjugates contributes to many biological processes, from glycan-based molecular recognition developmental events, such regeneration in the nervous system. Echinoderms, which have a close phylogenetic relationship with chordates, an important group marine invertebrates for body regeneration. Although major roles known, their role glycosylation profile system sea urchins is...
Oligosaccharides from regular milk and lactose-free were analyzed by Electrospray Ionization interface coupled with Ion Trap Mass Spectrometry (IT-MS). The negative mode mass spectrometry of sugar compositions was obtained either direct infusion Liquid Chromatography (LC). Hexose (Hex) the other oligomeric components observed in both milk. While lactose derivatives (deprotonated dimer, chloride adducts, dimer) have seen to be dominated, monosaccharide (Hex-H2O, Hex, Hex-Cl) as abundant which...