A5032374590- Systemic Lupus Erythematosus Research
- Ocular Diseases and Behçet’s Syndrome
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Mesenchymal stem cell research
- COVID-19 Clinical Research Studies
- Wound Healing and Treatments
- Birth, Development, and Health
- Cardiovascular Disease and Adiposity
- COVID-19 and Mental Health
- Reproductive Biology and Fertility
- Smoking Behavior and Cessation
- Genital Health and Disease
- Corneal surgery and disorders
- Neuroscience of respiration and sleep
- Adipose Tissue and Metabolism
- Vasculitis and related conditions
- Cardiac, Anesthesia and Surgical Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Neuroendocrine regulation and behavior
- Chemotherapy-induced organ toxicity mitigation
- Corneal Surgery and Treatments
- Inflammasome and immune disorders
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Ocular Surface and Contact Lens
Ege University
2011-2024
Stem Cell Institute
2024
Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie
2022
Urology Foundation
2021
NIHR Birmingham Biomedical Research Centre
2021
University of Birmingham
2021
Yorkshire Cancer Research
2021
Association for Cancer Surgery
2021
Introduction: Diabetic burn wounds and ulcers are significant complications of diabetic patients.The aim this study was to investigate the use platelet rich-plasma (PRP) and/or keratinocytelike cells (KLCs) in thermal wound rat model evaluate EGF, FGF-2, TGF-β1, COL1α2, MCP-1 VEGF-α as healing markers at gene expression level.Methods: In study, we used adipose tissue source mesenchymal stem (MSCs) differentiated MSCs into KLCs.KLCs were characterized transferred areas on dorsum...
Several studies have shown increased oxidative stress in patients with pre-diabetes and newly diagnosed Type 2 diabetes mellitus (T2DM). It has been proposed that initiates insulin resistance genetically predisposed individuals. The aim of this study was to evaluate the markers offspring T2DM.We examined 60 lean normoglycemic diabetics, 52 age, sex body mass index matched subjects without family history T2DM as controls. Anthropometric, biochemical carotid intima media thickness (IMT)...
Despite the promising potential of cell-based therapies developed using tissue engineering techniques to treat a wide range diseases, including limbal stem cell deficiency (LSCD), which leads corneal blindness, their commercialization remains constrained. This is primarily attributable limited sources, use non-standardizable, unscalable, and unsustainable techniques, extended manufacturing processes required produce transplantable tissue-like surrogates. Herein, we present first...
The signaling pathway OPG/RANK/RANKL is a key in maintaining the balance between activity of osteoblasts and osteoclasts order to prevent bone loss. In this study, our aim was assess effects long-term nicotine exposure on plasma RANKL OPG levels, tissue immunoreactivities, mineral density (BMD) scores rats.Thirty-six Swiss Albino rats weighing 70 ± 10 g were divided into three groups. While controls (n = 12) only given normal drinking water, for low-dose (LDN) group 0.4 mg/kg/day; high-dose...
The aim of this study is to investigate the effects miR150 transfection on NK-like cells differentiated from adipose tissue derived mesenchymal stem (AD-MSCs).NK-like were AD-MSCs and activated by transfection. Transfected/non-transfected characterized immunohistochemical RT-PCR analyzes. Apoptotic efficiency transfected/non-transfected pancreatic cancer PANC1 determined TUNEL RT-PCR.In miR150-transfected cells, increased expression NK cell-specific genes such as GKMB, KIR2DL2, CD16, CD56,...
<b>Background:</b> Most women do not stop smoking either during pregnancy or in the lactation period. This study was carried out to investigate effect of long term per oral pre/postnatal low/high dose nicotine exposure on fetal plasma/tissue oxidant-antioxidant status rats. <b>Methods:</b> The groups were composed pups whose parents used did use and divided into 3 groups, each consisting 10 rats; control group (normal drinking water), low high according (0.4 mg/kg 6.0 BW/day, respectively)...
Introduction: The objective of this study was to evaluate a dressing material on ischemic wound model in diabetic rats. Study conducted during the months June 2012-March 2013 at Ege University Izmir, Turkey.Materials and Methods: Spraque Dawley rats weighing 200-250 g obtained from an experimental animal production center (Saki YeniliAnkara,Turkey) were used study. Animals randomly assigned (n= 20) nondiabetic groups. After diabetes induction creation, animals within each group two groups by...
The aim of this study was to investigate the possible protective effects apelin, which is known have antioxidant and anti-inflammatory effects, on changes in neurogenesis newborns pregnant rats with L-NAME-induced preeclampsia. Wistar albino female were divided into four experimental groups: Control, Apelin, Preeclampsia + Apelin. Blood pressure measured 5th, 11th 17th days gestation, urine protein analyzed from samples collected for 24 h 6th, 12th 18th serum creatinine samples. Maternal...
To investigate the effect of nicotine exposure starting before coitus and continuing during pregnancy lactation period on delivery rate, fetal growth addiction in rats.Ten female Swiss Albino rats were divided into 2 groups as group (NG) (n=5), control conceived by adding male to each group. While was given only normal drinking water, 0.4 mg/kg body weight (BW)/day NG water. After delivery, BWs pups recorded weekly for 6 weeks their water preferences assessed. Meanwhile, continued receive...
Nicotine is one of the main chemicals in cigarettes responsible for addiction formation. Many researches investigating effects nicotine on coronary heart disease and atherosclerosis have been published. The robustness endothelial cells very important development atherosclerosis. aim this study to evaluate effect exposure indicators function either by examining vascular reactivity aorta taken from rats exposed during prenatal (starting mating period) postnatal periods (6 weeks after...