A5055636982- Plant-Derived Bioactive Compounds
- Reproductive System and Pregnancy
- Hearing, Cochlea, Tinnitus, Genetics
- Asthma and respiratory diseases
- Cancer-related Molecular Pathways
- Ear Surgery and Otitis Media
- Laser Applications in Dentistry and Medicine
- Cell Adhesion Molecules Research
- Cancer Cells and Metastasis
- Bone health and treatments
- Growth Hormone and Insulin-like Growth Factors
- Bone Tissue Engineering Materials
- PI3K/AKT/mTOR signaling in cancer
- Endometriosis Research and Treatment
- Bee Products Chemical Analysis
- Cancer, Stress, Anesthesia, and Immune Response
- Tannin, Tannase and Anticancer Activities
- Reproductive Biology and Fertility
- Angiogenesis and VEGF in Cancer
- Sarcoma Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Metabolism, Diabetes, and Cancer
- Nitric Oxide and Endothelin Effects
- Dermatologic Treatments and Research
- Bladder and Urothelial Cancer Treatments
Izmir University
2017-2022
İzmir University of Economics
2016-2022
Ali Osman Sonmez Oncology Hospital
2020
Manisa Celal Bayar University
2009-2018
Hamedan University of Medical Sciences
2017
Russian Cancer Research Center NN Blokhin
2012
Adli Tıp Kurumu
2010
ABSTRACT Objective: To investigate the effects of systemically given propolis on expanded premaxillary suture in a rat study model. Materials and Methods: The 24 rats were randomly divided into three groups—only expansion (OE), plus (PRO), nonexpansion (control) groups. After 5-day period was completed, OE PRO groups underwent 12 days mechanical retention. At end this period, animals euthanatized their pre-maxillae dissected fixed. Histomorphometric examination performed to determine number...
Cancer is a common cause of death worldwide. Approximately 80% cancer patients use complementary or alternative medicines for treatment. Caffeic acid phenethyl ester (CAPE), the main active component propolis, exhibits cytotoxic, antiproliferative and anti-cancer effects. Despite its anticancer effects CAPE no known harmful toward normal cells. We investigated on angiogenesis, apoptosis oxidative stress using MDA MB-231, N2a COLO 320 cell lines treatments at 24 48 h. A two dimensional...
Besides maintaining a physical barrier with adherens junctional (AJ) and tight proteins, airway epithelial cells have important roles in modulating the inflammatory processes of allergic asthma. E‑cadherin β‑catenin are key AJ proteins that involved remodeling. Various mediators such as transforming growth factor‑β (TGF‑β), epidermal factor (EGF), fibroblast (FGF), platelet derived (PDGF), insulin‑like (IGF), tumor necrosis factor‑α (TNF‑α) angiogenic factors, vascular endothelial (VEGF),...
Mechanisms of hypoxia-related angiogenesis are important for uterine smooth muscle tumors. Factors that related to during hypoxia include vascular endothelial growth factor (VEGF), inducible 1α (HIF1α), T-cell intracellular antigen1 (TIA1), eukaryotic translation initiation 2α (eIF2α) and thrombospondin 1 (TSP1). We investigated immunoreactivities VEGF, HIF1α, TIA1, eIF2α TSP1 using an indirect immunoperoxidase method formalin fixed, paraffin embedded tumors had been diagnosed as leiomyoma...
ABSTRACT In this study, we compared the effects of collagenase and Centella asiatica in rat model. Twenty‐seven female rats were divided into three groups, two full‐thickness wounds made for each animal. Collagenase ointment was applied topically to Group I C. II rats. III, no treatment applied. On third day treatment, on left side animals group excised. fifth eighth treatments, same procedure performed remaining animals. Indirect immunohistochemical examination detect transforming growth...
Embryonic molecules and cancer stem cell signaling resemble each other, they organize modality. We hypothesized that similar immunohistochemical expressions between tumor spheroids patients' samples compared with clinical relevance would give an important clue in prognosis.Immunohistochemical expression of c-kit, Notch1, Jagged1, Delta1 50 cases primary ovarian tumors (10 endometrioid, 10 serous, mucinous adenocarcinoma, borderline tumors) MDAH-2774 were investigated. Results both...
Mammalian target of rapamycin (mTOR) is a member the PI3K/Akt/mTOR signaling pathway that participates in cell growth, proliferation, protein synthesis, transcription, angiogenesis, apoptosis and autophagy. We investigated role mTOR other molecules rat uterus during implantation. Female pregnant rats were divided into three groups: embryonic days (ED) 4.5, 5.5 6.5 according to vaginal smears. Immunohistochemical staining mTORC1, mTORC2, IGF1, PI3K, pAkt1/2/3, ERK1 pERK1/2 was performed on...
The aim of the current study was to determine whether MWCNT-based scaffold has a suitable structure for cell growth and provides biocompatible environment human MDA-MB-231 lines. nanostructured scaffolds were produced by plasma-enhanced chemical vapor deposition (PECVD) technique. cells seeded on MWCNTs-textured silicon pristine surfaces. After 1 week culturing, prepared SEM analysis immunocytochemical staining performed two groups (MWCNT surface), using MMP-2, MMP-9, PI3K, AKT NF-κB primary...