A5063365771- Endodontics and Root Canal Treatments
- Anesthesia and Neurotoxicity Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Dental materials and restorations
- Reproductive Biology and Fertility
- Birth, Development, and Health
- Urological Disorders and Treatments
- Neuroscience and Neuropharmacology Research
- Ovarian function and disorders
- Pediatric Urology and Nephrology Studies
- Testicular diseases and treatments
- Neonatal Respiratory Health Research
- Oral and Maxillofacial Pathology
- Kidney Stones and Urolithiasis Treatments
- Cardiac Ischemia and Reperfusion
- Oral microbiology and periodontitis research
- Dental Radiography and Imaging
- S100 Proteins and Annexins
- Esophageal and GI Pathology
- Surgical Sutures and Adhesives
- Chemotherapy-induced cardiotoxicity and mitigation
- Reproductive System and Pregnancy
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Coenzyme Q10 studies and effects
Hacettepe University
2016-2025
Erzincan Binali Yıldırım University
2023
Hacettepe University Hospital
2023
State Hospital
2023
Liv Hospital
2015
University of Sarajevo
2015
Russian Cancer Research Center NN Blokhin
2012
Turkish Society of Hematology
1997-2011
Manisa Celal Bayar University
2010
Adli Tıp Kurumu
2010
ABSTRACT Background: This study was designed to elucidate the in vivo efficacy of epidermal growth factor (EGF) on wound healing non diabetic and rats. Methods: Ninety‐six male Wistar‐Albino rats were randomly divided into six groups. Saline‐moistened gauze, pure gelatin or EGF gelatin‐microsphere dressings used a dermal excision model both normal streptomycin‐induced Wound evaluated day 7 14. Reduction area, hydroxypyroline content tensile strength each rat. Tissue samples taken from wounds...
Background/aimPeripheral nerve injuries (PNI) are debilitating disorders affecting predominantly the younger generation, often leading to significant disabilities. Current treatment strategies inadequate in addressing complex nature of these injuries. Peripheral healing and functional recovery crucial components both pathophysiology therapeutic approach. High fructose corn syrup (HFCS) is a frequently used sweetener several beverages foods. And it associated with metabolic disturbances...
The purpose of this in vitro study was to compare the efficacy a new chemomechanical caries removal agent, Carisolv (MediTeam AB, Sävedalen, Sweden), with conventional slow-speed rotary instrument (bur). Fourteen extracted human molar teeth deep dentine and no enamel coverage were selected for study. Their laser fluorescence values over 30 (DIAGNOdent; KaVo, Biberach, Germany). After sectioned through centre carious lesion, one half removed drilling (bur); other gel. Removal continued until...
Cytotoxicity of root canal irrigants is important due to their close contact with host tissues. The aim this study was assess the cytotoxic effect NaOCl 3%, Chx 2%, and MTAD on rat periodontal ligament fibroblasts, at 0.1 100 µl/mL, using WST-1 colorimetric method.Rat ligamental fibroblasts were exposed viability assessed after 1, 24, 48, 72 h. measurements determined assay, a micro ELISA reader.At ml/L all 3 strongly cytotoxic, although CHX less so than MTAD. At concentration, only...
The aim of this study was to evaluate the cytotoxicity three types calcium silicate-based endodontic cement after different incubation periods with human periodontal ligament fibroblasts. Human fibroblasts were cultured from extracted third molars and seeded in 96-well plates. MTA, enriched mixture (CEM) cement, Biodentine prepared added culture insert plates which immediately placed into containing cells. After 24, 48, 72 hours, cell viability determined WST-1 assay. Data analysed...
Recently, cytotoxic effects of statins on breast cancer cells have been reported. However, the mechanism anti-proliferative is currently unknown. Autophagy non-apoptotic programmed cell death, which characterized by degradation cytoplasmic components and as having a role in pathogenesis.To investigate atorvastatin MCF-7 human adenocarcinoma with respect to both autophagy apoptosis.Cell culture study.Cell viability was analyzed using WST-1 proliferation assay. Apoptosis determined TUNEL...
Odontomas are the most common odontogenic tumours.They usually asymptomatic and often discovered during routine radiography.Compound odontomas regularly calcified tissue that bear similarity to teeth or appear as a collection of small teeth.We report rare case compound odontoma in mandible an adult patient with clinical radiological features review literature.
Background Nasal mucociliary clearance has an important role in voiding the airways from inhaled foreign substances. This activity could be disturbed by environmental factors such as radiofrequency radiation. The aim of present study was to investigate short‐term and relatively long‐term effects 2100‐MHz radiation emitted a generator, simulating 3G‐mobile phone, on nasal septal mucosa rats. Methods Thirty Wistar albino rats were divided into 4 groups. There 6 Group A B, which served control...
To ascertain the presence of myofibroblasts in sacs associated with inguinal hernia children, through an ultrastructural evaluation using electron microscopy.Sacs were obtained from 10 boys and girls (of similar age, approximately 45 months) processed for microscopy. Thin sections examined specifically myofibroblasts.The showed classical microscopic features within all sacs, regardless gender origin.The persistence smooth muscle hinders obliteration processus vaginalis; are found association...
Abstract Objectives This study is aimed to evaluate the cleaning efficacy of five different irrigation systems as SonicMax, RinsEndo, EndoVac, passive ultrasonic (PUI), and manual needle (MNI) histologically presence organic structures penetration solution. Materials Methods Forty-two single-rooted, extracted human mandibular premolars were used in study. Each tooth was decoronated at cementoenamel junction root canals instrumented using ProTaper rotary instruments a crown-down manner. The...
To evaluate contralateral testicular blood flow by histological examination of arterioles during ipsilateral torsion.The study comprised two groups 20 male albino rats (weight 250-270 g). The control group underwent a sham operation, while in the second left testes were twisted clockwise 720 degrees. All bilateral orchidectomy 24 h after initial intervention. Three slides for each testis (n = 240) evaluated randomly unaware treatment to determine total number arterioles, percentage collapsed...
The goal of this in vitro study was to evaluate the relative biocompatibility four endodontic sealers on cell culture human fibroblast through cytotoxicity.Materials and Methods: In endodontics used GuttaFlow (Roeko)silicone based sealer, AH plus (De Tray-DENTSPLY) epoxy resin based, Apexit (Vivadent) calcium hydroxide Endorez (Ultradent) methacrylate sealer.Sealers were tested primary lines gingival fibroblasts.Experiments preformed laboratories Hacettepe University Ankara, Turkey Faculty...
Investigating the effects of coenzyme Q10 on organ damage and survival mice in cecal ligation perforation (CLP) model sepsis.Coenzyme is an antioxidant molecule playing important role mitochondria. Mitochondrial dysfunction mechanism sepsis pathophysiology.Nintyfour Swiss Albino male were divided into 8 groups. CLP was performed Group I. Coenzyme Q10, 100 mg/kg subcutaneously, given 5 hours after to II 20 III. Sham operation IV, subcutaneously sham V VI. No VII; VIII. Antibiotics fluid...
Doxorubicin (dox) is a chemotherapeutic agent widely used against various tumors. However, the clinical use of this limited due to organ toxicities. Taurine an intracellular free β-amino acid with antioxidant properties. The present study investigated protective mechanism taurine on dox-induced hepatotoxicity.In total, 31 male Sprague-Dawley rats were in study. control group received intraperitoneal (i.p.) 0.9% NaCl alone for 14 days; (Tau) i.p. 150 mg/kg body weight/day dox days 12, 13, and...