A5070409008- Vector-borne infectious diseases
- vaccines and immunoinformatics approaches
- Parasitic Infections and Diagnostics
- Toxoplasma gondii Research Studies
- Rabies epidemiology and control
- Viral Infections and Vectors
- Bartonella species infections research
- Cultural and Sociopolitical Studies
- Immunotherapy and Immune Responses
- Amoebic Infections and Treatments
- SARS-CoV-2 and COVID-19 Research
- Yersinia bacterium, plague, ectoparasites research
- Herpesvirus Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Parasitic infections in humans and animals
- Historical Turkish Studies
- Coccidia and coccidiosis research
- Insect and Pesticide Research
- Zoonotic diseases and public health
- Helminth infection and control
- Metabolism and Genetic Disorders
- Blood groups and transfusion
- Bacteriophages and microbial interactions
- Turkish Literature and Culture
- Tryptophan and brain disorders
Biruni University
2022-2024
Ruhr University Bochum
2024
Ege University
2019-2024
University of Duisburg-Essen
2024
Bridge University
2020
Abstract In the genome of SARS-CoV-2, 5′-terminus encodes a polyprotein, which is further cleaved into 15 non-structural proteins whereas 3′ terminus four structural and eight accessory proteins. Among these 27 proteins, present study aimed to discover likely antigenic epitopes be used for development vaccine or serodiagnostic assay using an in silico approach. For this purpose, after full analysis SARS-CoV-2 Wuhan isolate variant that are detected frequently, surface including spike,...
Blastocystis sp. is one of the most frequently detected intestinal parasites in humans and can inhabit a wide range animals.Close contact with animals transmission factors sp.infection humans.In this study, we aimed to investigate molecular prevalence subtypes stray cats living İzmir, Turkey.The PCR targeting barcode region SSU rRNA gene was performed DNA samples isolated from feces (n:465) presence sp.PCR positive were sequenced for subtyping analysis.Among analyzed, sp.DNA 17 (3.65%) them...
Abstract Purpose Anaplasmosis is a tick-borne disease which caused by different Anaplasma species. Among species, A. ovis can infect sheep and goats cause ovine anaplasmosis. In this study, the prevalence of spp. was investigated in 31 breeds from regions Türkiye. Method PCR targeting MSP-4 gene blood samples (n = 366) collected Also, some positive were sequenced for species identification sub-cluster analyses. Results The molecular 43.9% (161/366). Anatolian Merino 10) Akkaraman 11) breeds,...
Naegleria fowleri, the brain-eating amoeba, is a free-living amoeboflagellate with three different life cycles (trophozoite, flagellated, and cyst) that lives in variety of habitats around world including warm freshwater soil. It causes disease called naegleriasis leading meningitis primary amoebic meningoencephalitis (PAM) humans. N. fowleri transmitted through contaminated water sources such as insufficiently chlorinated swimming pool or tap water, swimmers are at risk. found all over...
The emergence of tick-borne disease is increasing because the effects temperature rise driven by global warming. In Turkey, 19 pathogens transmitted ticks to humans and animals have been reported. Based on this, this study aimed investigate including Hepatozoon spp., Theileria Babesia Anaplasma Borrelia Bartonella spp. in tick samples (n = 110) collected from different hosts (dogs, cats, cattle, goats, sheep, turtles) molecular methods.To meet objective, were identified morphologically at...
Abstract Background Cryptosporidium spp. are obligate intracellular apicomplexan parasites transmitted to humans and other animals by contaminated water, food, or direct contact. They mainly cause gastrointestinal symptoms, although subclinical infections also common. Cats primarily infected host-adapted felis while C. parvum muris have been detected in some cases. In this study, the molecular prevalence of was investigated screening 399 fecal samples collected from stray cats using nested...
Bartonella spp. are vector-borne pathogens that cause zoonotic infections in humans. One of the most well-known these is cat-scratch disease caused by henselae and clarridgeiae, with cats being major reservoir for two bacteria. Izmir, Turkey home to many stray cats, but their potential role as a transmission humans has not been investigated yet. Therefore, aim this study was investigate prevalence species genetic diversity living Izmir.
Discovery of new Toxoplasma gondii serotyping epitopes is important due to reports showing the influence genotype on severity toxoplasmosis. In Turkey, genotypes belonging type II, III and Africa 1 lineages were mainly detected. The present study focused find out with high discriminative capacity serotype these using well characterized strains isolated from Turkey.To meet this objective, GRA6 GRA7 genes sequenced lineages, B cell inside sequences predicted by Bcepred additional docking...
• Vitamin D is vital for bone health, calcium and phosphorus regulation, immune system modulation, bile acid detoxification. The derived DBP allelic variant predicted to have stronger more stable binding with vitamin D, compared the wild-type variant.
Abstract Severe acute respiratory syndrome coronavirus 2 had devastating consequences for human health. Despite the introduction of several vaccines, COVID-19 continues to pose a serious health risk due emerging variants concern. DNA vaccines gained importance during pandemic their advantages such as induction both arms immune response, rapid development, stability, and safety profiles. Here, we report immunogenicity protective efficacy vaccine encoding spike protein with D614G mutation...
Abstract Background Bartonella henselae is one of the most commonly identified species associated with several human diseases. Although B. was detected in humans and cats Turkey, they have not been genotyped previously. Therefore, this study aimed to genotype samples (n = 44) isolated from stray using multi-locus sequence typing (MLST) method. For aim, eight different housekeeping markers were amplified by nested PCR then sequenced reveal types (STs) samples. Results Allelic profiles...