A5050144006- Research on Leishmaniasis Studies
- Viral Infections and Vectors
- Trypanosoma species research and implications
- Vector-borne infectious diseases
- Food Allergy and Anaphylaxis Research
- Venomous Animal Envenomation and Studies
- Rabies epidemiology and control
- Leptospirosis research and findings
- Healthcare and Venom Research
Ege University
2019-2024
Leishmania RNA virus (LRV) is a double-stranded (dsRNA) infecting some strains and triggering destructive hyperinflammatory response in mammalian hosts the New World. There limited knowledge of presence this Old World species its role outcome disease. We aimed to investigate LRV species/strains from Turkey. Twenty-nine previously identified isolates (24 L. tropica, 2 infantum, 3 major) were examined for positivity using dsRNA visualization agarose gel after total nucleic acid extraction...
Alpha-Gal syndrome (AGS) manifests as an intricate allergic response characterised by the formation of specific immunoglobulin E (IgE) antibodies targeting a carbohydrate termed galactose-a-1.3-galactose (a-Gal). antigens, which play role in AGS, have been detected salivary glands and saliva various tick species, especially
Background Leishmaniasis, caused by Leishmania protozoan parasites transmitted Phlebotomine sand flies, is a significant public health concern in the Mediterranean basin. Effective monitoring of -infected flies requires standardized tools for comparing their distribution and infection prevalence. Consistent quantitative real-time PCR (qPCR) parameters efficient DNA extraction protocols are crucial reliable results over time across regions. However, absence technical recommendations detection...
Abstract Leishmaniasis is a parasitic disease infecting animals and humans. Two clinical forms (Visceral cutaneous leishmaniasis) four species are reported to be present in Turkey. Several studies have investigated canine human leishmaniasis Turkey but no study was performed screen the infection among wild rodents, so far. The aims investigate role of small rodents as reservoir for Leishmania spp. different regions Formalin-preserved tissue samples (spleen, liver, lung) 712 from 30 provinces...
Abstract In the past decade, leishmaniasis seems to be re‐emerging in Balkan countries. There are serious implications that Kosovo is a visceral endemic region with autochthonous transmission; nevertheless, surveillance of vectors, reservoirs or disease not yet established. Gaining knowledge about sandfly vector species prerequisite for development monitoring and control plan future. After long gap research over 70 years, studies were resumed 2014. During this presence/absence study, nine...
Abstract Toscana virus (TOSV) is a prominent arthropod‐borne viral agent of human central nervous system infections occurring in the Mediterranean region. The main transmission route to susceptible individuals involves sandflies as vectors. Despite several reports revealing widespread TOSV activity Turkey, vectors remained unidentified. A sandfly field survey was carried out five provinces Central, Southeast and Anatolia 2017 identify related sandfly‐borne phleboviruses Leishmania parasites,...
Leishmaniasis, a parasitic infection affecting both humans and animals, is increasingly spreading across Mediterranean European regions, largely driven by human migration environmental changes. In countries like Türkiye Europe, which have seen large influxes of migrants, the incidence cutaneous leishmaniasis (CL) rising, with cases now appearing in cities where disease was previously undocumented. these non-endemic areas, physicians unfamiliar characteristic lesions may misdiagnose CL,...
Abstract Background Leishmaniasis, caused by Leishmania protozoan parasites transmitted Phlebotomine sand flies, is a significant public health concern in the Mediterranean basin. Effective monitoring of -infected flies requires standardized tools for comparing their distribution and infection prevalence. Consistent quantitative PCR (qPCR) conditions efficient DNA extraction protocols are crucial reliable results over time across regions. However, there currently lack technical...
Leishmania RNA virus was detected the first time in New World species. Recent studies were also showed presence of 2 (LRV2) Old Word species including Turkish L. major and tropica isolates. This study aimed to increase sensitivity qPCR with a modification denaturation step cDNA preparation protocol.In this study, LRV2+ three major, two strains control strain (MHOM/SU/73/5-ASKH) included. Total isolation done using different numbers promastigotes (108, 105 103). Before synthesis, samples...