Lütfiye Nilsun Altunal

ORCID: 0000-0003-4794-9283
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Long-Term Effects of COVID-19
  • Antibiotic Use and Resistance
  • Bacterial Infections and Vaccines
  • Hepatitis B Virus Studies
  • Nosocomial Infections in ICU
  • COVID-19 and Mental Health
  • Pneumonia and Respiratory Infections
  • Hepatitis C virus research
  • Diabetic Foot Ulcer Assessment and Management
  • Diagnosis and treatment of tuberculosis
  • Herpesvirus Infections and Treatments
  • Liver Disease Diagnosis and Treatment
  • Vaccine Coverage and Hesitancy
  • Antimicrobial Resistance in Staphylococcus
  • Blood donation and transfusion practices
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Brucella: diagnosis, epidemiology, treatment
  • Inflammatory Biomarkers in Disease Prognosis
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Plant Virus Research Studies
  • Peripheral Neuropathies and Disorders
  • HIV, TB, and STIs Epidemiology
  • Toxoplasma gondii Research Studies

Sağlık Bilimleri Üniversitesi
2018-2024

Ümraniye Eğitim ve Araştırma Hastanesi
2018-2024

Universidad CES
2022-2024

University of Health Science
2018-2023

University of Health Sciences
2023

Kocaeli Üniversitesi
2017

Emel Azak Ahmet Sertçelik Gülden Ersöz Güven Çelebi Fatma Eser and 89 more Ayşe Batırel Yasemin Çağ Zeynep Türe Derya Öztürk-Engin Meltem Arzu Yetkin Sedat Kaygusuz Aslıhan Candevir Ermira Tartari Jordi Rello Emine Alp Ali Seydi ALPAY Arzu Altunçekiç Yıldırım Aslı Vatan Aysun Yahşi Ayşe Kaya Kalem Ayşe Sağmak Tartar Ayşegül Tuna Banu Karaca Belgin Coşkun Burcu Gonulal Canan Demir Davut İpek Dilsat Tepe Duru Mıstanoglu Ozatag Edanur Sezer Emine Sehmen Emine Ünal Evren Emsal Aydın Ertuğrul Güçlü Esma Eren Esmeray Mutlu Yılmaz Fatma Yılmaz Karadağ Ferhan Kerget Filiz Bayar Gamze Kalın Ünüvar Gülden Eser Karlıdağ Gülfem Akengin Öcal Gülnur Kul Güneş Şenol Gürdal Yılmaz Haluk Erdoğan Handan Alay Hande Arslan Hasip Kahraman Hatun Öztürk Çerik Hülya Çaşkurlu İlknur Erdem İlknur Esen Yıldız Kıvanç Şerefhanoğlu Kübra DEMİR ÖNDER Lütfiye Nilsun Altunal Mehmet Çelik Mehmet Reşat Ceylan Merve Sefa Sayar Metehan Özen Muharrem Guler Mustafa Uğuz Mustafa Yı́ldı́rı́m Esra Koçoğlu Müge Ayhan Müge Toygar Deniz Nagehan Didem Sarı Nazan Tuna Nevin İnce Ozlem Bayrak Öznur Ak Ramazan Gozukuçuk Recep Balık Salih Atakan Nemli Selda Aslan S. Sahin Semiha Solak Grassie Serpil Ünlü Sevil Alkan Sibel Altunışık Toplu Suna Secil Ozturk Deniz Süheyla Kömür Süleyman Koç Saban Incecik Tuba Yalçın Tuna Demırdal Türkan Tüzün Verda Tuna Yasemin Çakır Yasemin Ersozlu Yeşim Aybar Bilir Yeşim Uygun Kızmaz Yıldız Olçar Zerrin Yuluğkural

Abstract Background The core components (CCs) of infection prevention and control (IPC) from World Health Organization (WHO) are crucial for the safety quality health care. Our objective was to examine level implementation WHO (IPC CC) in a developing country. We also aimed evaluate care-associated infections (HAIs) antimicrobial resistance (AMR) intensive care units (ICUs) association with implemented IPC CCs. Methods Members Turkish Infectious Diseases Clinical Microbiology Specialization...

10.1186/s13756-023-01208-0 article EN cc-by Antimicrobial Resistance and Infection Control 2023-02-13

The current knowledge about novel coronavirus-2019 (COVID-19) indicates that the immune system and inflammatory response play a crucial role in severity prognosis of disease. In this study, we aimed to investigate prognostic value systemic biomarkers including C-reactive protein/albumin ratio (CAR), nutritional index (PNI), neutrophil-to-lymphocyte (NLR), lymphocyte-to-monocyte (LMR), platelet-to-lymphocyte (PLR) patients with severe COVID-19.This single-center, retrospective study included...

10.1177/11772719211027022 article EN cc-by-nc Biomarker Insights 2021-01-01

Protective neutralizing antibody titers reduce in time after COVID-19 vaccinations, as individuals who have had COVID-19. This study aimed to evaluate the safety and immunogenicity of CoronaVac TURKOVAC vaccines used a booster dose primary vaccination. double-blind, randomized, controlled, phase II, multicenter included healthy male female adults (18–60 years) were vaccinated with two doses vaccine did not exceed duration at least 90 days maximum 270 from second Among 236 eligible...

10.1080/21645515.2022.2122503 article EN cc-by-nc-nd Human Vaccines & Immunotherapeutics 2022-10-31

Objective: To evaluate the prevalence of Toxoplasma gondii, rubella, and cytomegalovirus (CMV) among pregnant Turkish women as well Syrian refugees in Istanbul.Methods: Among who were admitted to Esenler Maternity Children Hospital İstanbul between January 2014 2015, antibodies against T. CMV measured using micro-ELISA method.The test results evaluated retrospectively.Results: Out a total 1066 screened present study, 963 (90.3%) Turkish, 103 (9.7%) refugees.IgM positivity rates determined...

10.14744/scie.2018.66375 article EN Southern Clinics of Istanbul Eurasia 2018-01-01

Introduction: Since the beginning of pandemic, factors associated with mortality in patients corona virus infection disease 2019 (COVID-19) have been investigated. Comorbidities and increased age frequently reported to be mortality. We aimed evaluate unfavorable outcome COVID-19 at an early period pandemic.
 Methodology: This single center, retrospective, observational study was conducted among laboratory confirmed hospitalized between March 11 May 5, 2020, Umraniye Training Research...

10.3855/jidc.15411 article EN cc-by The Journal of Infection in Developing Countries 2022-03-31

IntroductionThe human population is aging at an astonishing rate. The aim of this study to capture a situation snapshot revealing the proportion individuals aged 65 years and over among inpatients in healthcare institutions Turkey prevalence type infections patient group order draw road map.Materials MethodsHospitalized patients any 62 hospitals 29 cities across on February 9, 2017 were included study. Web-based SurveyMonkey was used for data recording evaluation system.ResultsOf 17,351 5871...

10.1016/j.ijid.2020.08.046 article EN cc-by-nc-nd International Journal of Infectious Diseases 2020-08-21

As the Modified Anticoagulation and Risk Factors in Atrial Fibrillation Score (M-ATRIA-RS) encompasses prognostic risk factors of novel coronavirus-2019 (COVID-19), it may be used to predict in-hospital mortality. We aimed investigate whether M-ATRIA-RS was an independent predictor mortality patients hospitalized for COVID-19 compare its discrimination capability with CHADS, CHA2DS2-VASc, modified CHA2DS2-VASc (mCHA2DS2-VASc)-RS.A total 1,001 were retrospectively analyzed classified into...

10.1016/j.amjms.2021.06.001 article EN other-oa The American Journal of the Medical Sciences 2021-06-06

Coronavirus disease-2019 (COVID-19) associated pneumonia may progress into acute respiratory distress syndrome (ARDS). Some patients develop features of macrophage activation (MAS). Elevated levels IL-6 were reported to be with severe disease, and anti-IL-6R tocilizumab has been shown effective in some patients. This retrospective multicenter case-control study aimed evaluate the efficacy hospitalized COVID-19 patients, who received standard care or without tocilizumab. Primary outcome was...

10.1007/s00296-021-04965-6 article EN other-oa Rheumatology International 2021-09-13

Introduction: Tuberculous lymphadenitis (TBLN) is the most common infectious etiology of peripheral lymphadenopathy in adults, Turkiye. This study aimed to identify demographic, clinical, and laboratory variables that differentiate TBLN from non-tuberculous (NTBLN), as well adults. Methodology: Patients who were over 18 years old referred disease outpatient clinics with complaints swollen lymph nodes, underwent node biopsy between 1 January 2010 March 2021, included this multicenter, nested...

10.3855/jidc.19502 article EN cc-by The Journal of Infection in Developing Countries 2024-05-30

Diabetes foot infection is a very important public health problem that causes serious problems, mortality, and high expenditures, one of the most complications diabetes mellitus. There are concerns approaches such as limited personal visits to doctors, avoidance hospitals, restrictions on nonemergency surgical procedures during coronavirus disease 2019 pandemic pose threat those with diabetic including ulcers (DFUs), ischemia, infection, resulting in increased limb loss mortality.

10.7547/22-073 article EN Journal of the American Podiatric Medical Association 2024-05-01

People living with human immunodeficiency virus (PLWH), the availability of modern antiretroviral drugs, have multiple comorbidities, which increase risk polypharmacy and potential drug-drug interactions (PDDIs). This is a particularly important issue for aging population PLWH. study aims to review prevalence factors PDDIs in era HIV integrase inhibitors. A cross-sectional, two-center, prospective observational was conducted on Turkish outpatients between October 2021 April 2022....

10.1089/apc.2022.0206 article EN PubMed 2023-03-01

Introduction: Coinfections of human immunodeficiency virus (HIV) and syphilis can be seen due to reasons such as common risk group transmission routes. In our study, it was aimed investigate the seroprevalence clinical features patients living with HIV. Materials Methods: Data 277 HIV-infected in Health Sciences University Umraniye Education Research Hospital between January 2016 December 2021 were evaluated retrospectively. Results: A total HIV included study. Two hundred thirty-five (85%)...

10.5578/flora.20239911 article EN cc-by-nc-sa Flora the Journal of Infectious Diseases and Clinical Microbiology 2023-03-03

The immunogenicity of vaccines decreases over time, causing a need for booster doses. This study aimed to present the long-term (Day 84) results double-blind, randomized, controlled, phase II Hybrid COV-RAPEL TR Study (NCT04979949), in which TURKOVAC or CoronaVac were used as after second dose primary vaccination with CoronaVac. A total 190 participants from Study, who had both Day 28 and 84 results, included. on 84, regarding neutralizing antibody positivity (Wuhan Delta variants)...

10.3390/vaccines11071234 article EN cc-by Vaccines 2023-07-12

Santral sinir sistemi (SSS) infeksiyonları farklı birçok mikroorganizma ile gelişebilen, beyin meninks ve parankiminin enflamasyonu karakterize hastalıklardır. Hastaların sağ kalımında erken tanı etkin tedavi uygulanması önem arz etmektedir. Çalışmamızda SSS infeksiyonu tanısıyla takip edilen hastaların klinik özelliklerinin irdelenmesi amaçlanmıştır.
 Ümraniye Eğitim Araştırma Hastanesi’nde Fatih Sultan Mehmet Şubat 2013 Aralık 2020 yılları arasında toplum kökenli tanısı konan 98...

10.54962/ankemderg.1048500 article TR ANKEM Dergisi 2021-12-27

10.5578/flora.67375 article EN cc-by-nc-sa Flora the Journal of Infectious Diseases and Clinical Microbiology 2019-06-15

Amaç: Santral sinir sistemi enfeksiyonları, acil tanı ve tedavi gerektiren morbidite mortalitesi yüksek enfeksiyonlardır. Hastanemizde takip edilen toplum kaynaklı santral (SSS) enfeksiyonları irdelenerek hasta yönetiminde yardımcı olmak amaçlanmıştır.Yöntem: Ümraniye Eğitim Araştırma Hastanesi’nde 2013 2020 yılları arasında SSS enfeksiyonu tanısı konan 56 retrospektif olarak değerlendirildi. Bulgular: Yedi yıl içinde hastanın klinik sınıflaması incelendi. En sık akut pürülan menenjit...

10.46237/amusbfd.771257 article TR Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi 2021-05-27

Objective: Frontline healthcare workers (HCW) exposed to coronavirus disease-2019 (COVID-19) patients at their work environment are a higher risk of acquiring the disease. The aim this study was research COVID-19 risks due occupational exposure HCW and clinical characteristics affected. Material Methods: In retrospective study, HCW, employed by Ümraniye Research Training Hospital, who were diagnosed with between 20th March 2020 May analysed. Results: A total 128 (3.8%) COVID-19. Most...

10.5336/medsci.2020-79883 article EN Turkiye Klinikleri Journal of Medical Sciences 2021-01-01

Objective: Candidemia is a life-threatening infection that causes high mortality rates in intensive care units (ICUs). This study aims to
 evaluate predictors of the outcome patients with candidemia ICU.
 Patients and Methods: observational, retrospective included Candida bloodstream (BSI) ICUs
 between 6 years episode. A binary logistic regression analysis was conducted to inspect association mortality.
 Results: The median age 74 68.5, 53.8% were men. C. parapsilosis...

10.5472/marumj.1367454 article EN Marmara medical journal 2023-09-27

Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory disease of the central nervous system (CNS) and commonly seen in children.It has seasonal peaks winter spring, consistent with its infectious etiologies, it rarely occurs as a reaction to vaccination.ADEM less common adults progresses more severe clinical course.Cases diagnosed ADEM by CNS demyelination after streptococcal meningitis have been reported adult patients.In this report, we present rare case...

10.4274/mjima.galenos.2023.2022.6 article EN cc-by-nc-nd Mediterranean Journal of Infection Microbes and Antimicrobials 2023-03-17
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