Gülay Okay

ORCID: 0000-0003-1616-2162
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Orthopedic Infections and Treatments
  • Streptococcal Infections and Treatments
  • Diverse Scientific Research Studies
  • HIV-related health complications and treatments
  • Viral Infections and Immunology Research
  • SARS-CoV-2 detection and testing
  • Animal Disease Management and Epidemiology
  • Pneumonia and Respiratory Infections
  • Hepatitis B Virus Studies
  • Liver Disease Diagnosis and Treatment
  • Pancreatitis Pathology and Treatment
  • Long-Term Effects of COVID-19
  • HIV/AIDS Research and Interventions
  • HIV Research and Treatment
  • Hepatitis C virus research
  • Pancreatic and Hepatic Oncology Research
  • Infectious Diseases and Tuberculosis
  • Infective Endocarditis Diagnosis and Management
  • Healthcare Systems and Reforms
  • COVID-19 Impact on Reproduction
  • Nosocomial Infections in ICU
  • Amoebic Infections and Treatments
  • Patient Satisfaction in Healthcare

Bezmiâlem Vakıf Üniversitesi
2016-2025

ORCID
2021

Office of Infectious Diseases
2020-2021

Istanbul University
2020

Bezmialem Foundation University Medical Faculty Hospital
2018

Ministry of Health
2014

Klebsiella pneumoniae is the most common endogen agent for nosocomial infections. In this study, mortality markers were investigated in patients with K. blood stream infection (NKp BSI).The characteristics of >16 years who had NKp BSI diagnosis by daily active surveillance between January 2012 and 2016 retrospectively evaluated. Patients died until 28th day clinical follow up those survived time statistically compared terms various risk factors.One hundred ninety included into study....

10.1186/s40064-016-3580-8 article EN SpringerPlus 2016-10-28

The recent pandemic of COVID-19 has caused a tremendous alarm around the world. Details infection process in host have significant bearings on both recovery from disease and correlates protection future exposures. One these factors is presence titers neutralizing Abs (NAbs) infected people. In current study, we set out to investigate NAbs recovered subjects discharged hospital full health. Serum samples total 49 documented consecutive were included study. All adults, serum collected during...

10.4049/jimmunol.2000840 article EN The Journal of Immunology 2020-09-25

This study aims to investigate the effects of nucleos(t)ide analogs (NAs) discontinuation in eligible patients accordance with Asian Pacific Association for Study Liver hepatitis B guideline and factors affecting clinical virological relapses.

10.5152/tjg.2024.23463 article EN The Turkish Journal of Gastroenterology 2024-01-05

Serum cytokine levels over the course of HIV infection usually increase with immunosuppression and decrease after antiretroviral treatment (ART).The aim study is to compare between HIV-infected patients (HIP) controls investigate relationship CD4+T cell count, HIV-RNA levels, levels.The subjects comprised ART-naive HIP (n=30) no comorbidities age-and sex-matched healthy controls. We measured IL-6, IL-1β, TNF-α, IFN-γ in serum samples at beginning month 6 ART controls.The mean age was 38.7...

10.2174/1570162x18666200712174642 article EN Current HIV Research 2020-07-12

Objective: Infectious spondylodiscitis (SD) is an infectious disease that rare and difficult to diagnose due its non-specific clinical features. In this study, we aimed describe the diagnostic features of spondylodiscitis.Methods: All patients who were diagnosed with SD at our hospital during a 7-year period from January 1, 2011 through December 31, 2017 included in study. Spondylodiscitis divided into following three types: pyogenic, tuberculous, brucellar. Clinical laboratory data...

10.12669/pjms.346.15717 article EN Pakistan Journal of Medical Sciences 2018-10-25

IntroductionThe human population is aging at an astonishing rate. The aim of this study to capture a situation snapshot revealing the proportion individuals aged 65 years and over among inpatients in healthcare institutions Turkey prevalence type infections patient group order draw road map.Materials MethodsHospitalized patients any 62 hospitals 29 cities across on February 9, 2017 were included study. Web-based SurveyMonkey was used for data recording evaluation system.ResultsOf 17,351 5871...

10.1016/j.ijid.2020.08.046 article EN cc-by-nc-nd International Journal of Infectious Diseases 2020-08-21

Objectives The response rate of patients to hepatitis B virus (HBV) vaccination receiving anti-tumor necrosis factor (TNF) agents is quite low. We aimed assess the efficiency HBV in with chronic inflammatory diseases (CIDs) anti-TNF as well healthy controls. also evaluated impact different factors on efficacy vaccination. Methods Patients CIDs and controls vaccinated for were included study during 2018–2019. An adequate immune an effective defined >10 IU/L > 100 IU/L, respectively....

10.1097/meg.0000000000001849 article EN European Journal of Gastroenterology & Hepatology 2020-07-14

Clostridium difficile is a Gram-positive, strict anaerobe, spore-forming bacterium. It can cause self-limiting mild diarrhea, severe pseudomembranous colitis, and fatal fulminant colitis. We aimed to investigate the changes in epidemiology incidence of C. infection our hospital database.Episodes toxin were identified database, data such as age, sex, community versus acquisition, intensive care follow-up, current or previous treatments with antibiotics within past 3 months, medication proton...

10.4103/sjg.sjg_44_19 article EN cc-by-nc-sa Saudi Journal of Gastroenterology 2019-01-01

Objective:The aim of this study is to investigate the effect hypertension on clinical severity and prognosis Coronavirus disease-2019 (COVID-19) patients. Methods:In retrospective observational study, reverse transcription-polymerase chain reaction (RT-PCR) positive COVID-19 patients over age 18 years who were hospitalized in Bezmialem Vakıf University between March May 2020 included.The divided into two groups as hypertensive non-hypertensive compared for clinical, laboratory...

10.14235/bas.galenos.2020.4978 article EN cc-by-nc-nd Bezmialem Science 2020-10-30

Background/objectives: The data regarding the microbial spectrum in necrotizing pancreatitis and its impact on mortality is limited. Therefore, this study, we aimed to investigate agents identified cultures their in-hospital 1-year all-cause mortality. Methods: Patients with were retrospectively included study. Based culture results, patients classified as either negative or positive acute pancreatitis. main outcomes of study identification isolated pancreatic necrosis assess in-hospital,...

10.1097/meg.0000000000001687 article EN European Journal of Gastroenterology & Hepatology 2020-02-24

Introduction:In this study, we aimed to determine the risk factors associated with inadequate empirical antibiotherapy (IEAT) and hospital-related mortality in elderly patients being treated for upper urinary tract infections (UTI).Materials Methods: This study included individuals aged 65 years over who were hospitalized after diagnosed of communityacquired UTI or community-onset healthcare-associated followed-up clinics and/or intensive care units (ICU) 33 hospitals between March September...

10.4274/mjima.galenos.2020.2020.5 article EN cc-by-nc-nd Mediterranean Journal of Infection Microbes and Antimicrobials 2020-06-02

Objective: This study aims to assess the effectivity of a rapid antibody test on detecting occupational exposure in healthcare professionals who have been working pandemic hospital since initial cases were seen our country. Methods: Prevention Coronavirus disease 2019 (COVID-19) institution was managed according Republic Turkey (T.C.) Ministry Health recommendations.Between 20.04.2020 and 05.05.2020, 376 high-risk (triage, emergency room, COVID-19 outpatient unit, clinic intensive care unit)...

10.14235/bas.galenos.2020.5018 article EN cc-by-nc-nd Bezmialem Science 2020-10-30

Several chronic illnesses, including HIV infection are associated with oxidative stress. In addition to itself, some antiretrovirals also increase stress while decreasing viral replication. To investigate the alterations in parameters and thiol-disulphide homeostasis people living who were receiving integrase inhibitor-based antiretroviral therapy.Thirty treatment-naive adult prospectively enrolled study. Sera collected from patients twice: at beginning of therapy (group 1) 6 months later...

10.26355/eurrev_202012_24033 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2020-12-01

Streptococcus parasanguinis, oral floranın doğal bir üyesidir. Fırsatçı patojen olup, düşük virülansı nedeniyle nadiren sistemik infeksiyonlara yol açar. Subakut infektif endokarditi olan hastalar, spondilodiskit gibi farklı klinik tablolar ile prezente olabilmektedir. Kuzey Irak’lı, 65 yaşında erkek hasta; yüksek ateş, kilo kaybı, bel ağrısı ve yürüyememe yakınmaları acil servisimize başvurdu. Veteriner hekim hastamızın üç yıl önce kolon kanseri cerrahi ışın tedavisi aldığı öğrenilmiştir....

10.17826/cukmedj.237550 article TR cc-by-nc-nd Cukurova Medical Journal (Çukurova Üniversitesi Tıp Fakültesi Dergisi) 2016-06-11

Pseudomonas stutzeri, non-fermentatif, gram negatif bakteridir. Nadiren enfeksiyonlara neden olur. Bu yazıda, ilk defa P. stutzeri’nin etken olduğu karaciğer apsesi olgusu sunulmuştur.

10.17826/cutf.254576 article TR cc-by-nc-nd Cukurova Medical Journal (Çukurova Üniversitesi Tıp Fakültesi Dergisi) 2016-10-08

Objective: Obesity might be a risk factor for patients with Coronavirus disease-19 .We aimed to investigate the association of obesity intensive care need and mortality caused by severe acute respiratory syndrome-CoV-2 (SARS-CoV-2) infection in this retrospective cohort.Methods: Between March 11 th May 1 st , 135 patients, who were treated our clinic, enrolled study.Body mass index (BMIs) grouped according as WHO criteria (<25 kg/m 2 : normal, 25 30 overweight, >30 obese).Results: Of 34.1%...

10.14235/bas.galenos.2020.5069 article EN cc-by-nc-nd Bezmialem Science 2021-02-01

The Hantaviruses within the Bunyaviridia family carried by rodents cause two different diseases in humans: Hemorrhagic Fever with renal syndrome (HFRS) and Hantavirus Pulmonary Syndrome (HPS).It is transmitted through contact secretion of infected or inhalation aerosols containing virus.In parts world, various virus subtypes disease.In HPS, mostly Sin Nombre, Andes, Laguna, Negra New York types are causative agents, whereas HFRS agents Dobrava, Puumala, Hantaan, Saaremaa Seoul.It more...

10.5799/ahinjs.02.2014.s1.0141 article EN Journal of Microbiology and Infectious Diseases 2014-06-01
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