- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Regulation of Appetite and Obesity
- Nosocomial Infections in ICU
- Adipokines, Inflammation, and Metabolic Diseases
- Dermatological and COVID-19 studies
- Infection Control in Healthcare
- COVID-19 Clinical Research Studies
- Gut microbiota and health
- Disaster Response and Management
- Urinary Tract Infections Management
- Lipid metabolism and disorders
- Essential Oils and Antimicrobial Activity
- Apelin-related biomedical research
- COVID-19 and healthcare impacts
- Drug-Induced Hepatotoxicity and Protection
- Bacterial Infections and Vaccines
- Diabetic Foot Ulcer Assessment and Management
- Patient Satisfaction in Healthcare
- Liver Disease and Transplantation
- Biomarkers in Disease Mechanisms
- Legionella and Acanthamoeba research
Elazığ Eğitim ve Araştırma Hastanesi
2019-2024
Sağlık Bilimleri Üniversitesi
2021-2024
University of Health Science
2024
Weatherford College
2023
Fırat University
2022-2023
ORCID
2021
We investigated the presence of asprosin (ASP), betatrophin, elabela (ELA), glucagon and subfatin (SUB) in milk mothers with gestational diabetes mellitus (GDM) compared their levels blood levels. also whether these peptides are synthesized by breast. 12 volunteer GDM 14 pregnant non-GDM control mothers. The were measured using ELISA tissue localization was determined immunohistochemistry. Breast contains ASP, ELA, SUB. amount ranged from highest to lowest colostrum, transitional mature...
Amaç: Yoğun bakım ünitelerinde yatan hastaların çeşitli klinik örneklerinden izole edilen Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa ve Acinetobacter baumannii’nin dağılımlarının, ilaç direnç oranlarının bu oranların yııllara göre değişiminin saptanması, böylece akılcı antibiyotik uygulaması direncin önlenmesine katkı sağlanması amaçlanmıştır. Gereç Yöntemler: İzole suşların kolistin, tigesiklin, meropenem, imipenem trimetoprim-sülfametoksazol oranları retrospektif...
Amaç: Çalışmamızda, 1 Mart 2019 -29 Şubat 2020 tarihleri pandemi öncesi (PÖ) ve 2020-1 2021 döneminde (PD) Elâzığ Fethi Sekin Şehir Hastanesi, Yoğun Bakım Üniteleri (YBÜ)'nden laboratuvarımıza gönderilen kan
Introduction: Some studies have indicated that adiponectin gene polymorphisms are related to coronary artery disease, and they play a role in the stabilization of atherosclerotic plaques. In this study, acute disease patients who had myocardial infarct with ST-elevation, chronic bypass graft operation, control group normal arteries were compared for polymorphisms. Material Methods: One hundred infarction ST-elevation (Group1), 100 operation (Group2), as group, angiography due suspected (CAD)...
Amaç: Genişlemiş spektrumlu β-laktamaz (GSBL) üretimi, Gram-negatif patojenlerde görülen en önemli antimikrobiyal direnç mekanizmasıdır.Bu çalışmada, toplum kökenli üriner sistem infeksiyonları (ÜSİ'ler)'ndan izole edilen Escherichia coli ve Klebsiella spp.türlerinde GSBL üretim sıklığı antibiyotik oranlarının araştırılması amaçlanmıştır.Yöntemler: Bu geriye dönük kesitsel araştırmada, ÜSİ tanısı konulan 520 hastanın idrar kültüründe üreyen E. spp.izolatlarına ait üretimi duyarlılık test...
With the aging population, it is expected that diabetes and related complications will increase rapidly. The aim of this study was to examine signs symptoms diabetic foot infection in elderly individuals. Patients with were grouped as mild, moderate, severe. aged <65 years those who did not meet diagnosis excluded from study. Only first applications patients applied hospital multiple times evaluated. 314 included mean age 71.5 (±12). number 75 over 125 (39.8%). Of patients, 25.7% had...
Aim: To measure serum myeloperoxidase (MPO) levels and to evaluate the relationship between this parameter histological findings in chronic hepatitis B C patients. Materials & methods: Three groups were formed: B, a control group. Serum MPO determined by ELISA. Results: level was found be higher both patient compared with group (p < 0.05). It also patients significant fibrosis mild Conclusion: Our results show that increased can used as an important noninvasive marker early detection of...
Aims: Cytokines play important roles in the immunopathogenesis of chronic hepatitis B (CHB) and C (CHC) infections.The aim this study was to examine changes serum levels interleukin (IL)-1β, IL-6 tumor necrosis factor (TNF)-α cytokines patients with CHB CHC, relationship these inflammation, disease progression fibrosis. Methods:We prospectively enrolled CHC control subjects from August 2016 2018.Liver biopsy samples were obtained as a part routine care.Serum IL-6, IL-1β, TNF-α determined by...
OBJECTIVE: Leptin plays an important role in inflammation and liver fibrogenesis viral diseases. In this study, determination of serum leptin level the effect levels on fibrosis chronic hepatitis B (CHB) C (CHC) cases were evaluated.MATERIALS AND METHODS: prospective clinical research a total 75 CHB patients, 36 CHC 51 control group included. Liver biopsy specimens scored using Ishak histological scoring system. Serum determined by ELISA method.RESULTS: Overall, 39 female while was male,...
Ochrobactrum anthropi, previously known as "Achromobacter group Vd", is a gram-negative, non-lactose-fermenting, obligate aerobic, indole-negative, oxidase-positive, urease-positive, motile bacillus. In recent years, it has emerged nosocomial infection agent especially in central venous catheters both immunosuppressed and immunocompromised individuals. this case report, 56-year-old female patient who underwent dialysis for two days week due to chronic kidney failure had O. anthropi isolated...
Amaç: Hastane kaynaklı enfeksiyonlar arasında yer alan yara enfeksiyonları az gelişmiş ve gelişmekte olan ülkeler için büyük bir sağlık sorunudur. Çalışmamızda enfeksiyonuna neden etkenler bu etkenlerin antibakteriyel duyarlılığının belirlenmesi amaçlanmıştır. 
 Gereç Yöntem: Retrospektif olarak 1290 sürüntü örneği değerlendirildi. Etken düşündüğümüz mikroorganizmaların tür düzeyinde tanımlanmaları, duyarlılıkları konvansiyonel VITEK-2 otomatize sistem ile çalışıldı.
 Bulgular:...
Abstract Objectives The aim of this study is to investigate the diagnostic and prognostic characteristics fetuin A B in chronic hepatitis (CHB) HBe Ag-negative infection (HCI) relationship between levels these proteins fibrosis CHB. Methods In study, we examined 98 patients with CHB, 58 HCI 42 control groups. Fetuin were determined via ELISA. Results Serum significantly higher group than cases (p=0.001). No significant difference CHB HCI. level was lower those mild (p=0.007). fibrosis;...
Background: In our study, antibody positivity was evaluated by two methods in vaccinated and unvaccinated people according to their demographic characteristics history of COVID-19. Methods: this venous blood samples were taken from patients who requested have COVID-19 antibodies hospital's outpatient clinics between February 2022 March 2022. Results: There no statistically significant difference when IgG compared the age ranges chemiluminescence immunochromatographic methods. When titers, it...
ÖZGiriş: Pseudomonas aeruginosa ve Acinetobacter baumannii'nin çok ilaca dirençli suşlarının neden olduğu infeksiyonlar, tüm dünyada yoğun bakım ünitelerinde önemli bir sorun oluşturmaktadır.Bu çalışmada ünitelerindeki çeşitli klinik örneklerden izole edilen P. A. baumannii suşlarına karşı antimikrobiyallerin in vitro aktivitelerinin araştırılması amaçlandı
Objectives: In this study, it was aimed to investigate the ischemia modified albumin (IMA) and IMA/albumin ratio (IMAR) relationship between these two parameters with fibrosis in patients chronic hepatitis B (CHB), e antigen negative infection (HBI) C (CHC).Materials Methods: This prospective study included 80 CHB, 50 HBI, 30 CHC 60 control groups.IMA level measured using rapid colorimetric analysis developed (albumin-cobalt binding test).IMAR calculated.Results: Forty-two of CHB cases were...
Amaç: Bu çalışmada, hepatit B enfeksiyonlu olgularda, karaciğer enflamasyonunu, hastalık progresyonunu takip etmede tanı için ve hasarının ilerleyip, kronik hastalığı komplikasyonların oluşmasını önlemek kullanılabilecek antioksidan glutatyonun serum düzeylerine bakıldı. Gereç Yöntem: Çalışmaya enfeksiyon’lu, ALT düzeyleri normal, HBV DNA Neg-&lt;104 c/ml 55 olgu ile sağlıklı, herhangi bir olmayan akut olmayan, 18 yaş üstü 40 kontrol grubu alındı. ELISA (Enzyme-Linked Immunosorbent...