A5043889004- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Cell Adhesion Molecules Research
- Dental Research and COVID-19
- Vector-borne infectious diseases
- Malaria Research and Control
- Bacterial biofilms and quorum sensing
- Brucella: diagnosis, epidemiology, treatment
- Bacterial Identification and Susceptibility Testing
- Public Administration and Governance
- Virology and Viral Diseases
- Rabies epidemiology and control
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Dermatological and COVID-19 studies
- Vector-Borne Animal Diseases
- Turkish Urban and Social Issues
- Enterobacteriaceae and Cronobacter Research
- Salmonella and Campylobacter epidemiology
- Diverse Scientific Research Studies
Ordu University
2015-2025
Şırnak University
2021-2023
Giresun University
2023
Hitit Üniversitesi Çorum Eğitim ve Araştırma Hastanesi
2017
Ondokuz Mayıs University
2009-2012
Bayburt State Hospital
2011
Gazi University
2008
It is known that inflammatory responses play an important role in the pathophysiology of COVID-19.In this study, we aimed to examine kynurenine (KYN) metabolism on severity COVID-19 disease AQ5.Seventy patients varying and 30 controls were included study. In addition classical laboratory parameters, KYN, tryptophan (TRP), kynurenic acid (KYNA), 3 hydroxykynurenine (3OHKYN), quinolinic (QA), picolinic (PA) measured with mass spectrometry.TRP, KYN:TRP ratio, KYNA, 3OHKYN, PA, QA results found...
Abstract Background The core components (CCs) of infection prevention and control (IPC) from World Health Organization (WHO) are crucial for the safety quality health care. Our objective was to examine level implementation WHO (IPC CC) in a developing country. We also aimed evaluate care-associated infections (HAIs) antimicrobial resistance (AMR) intensive care units (ICUs) association with implemented IPC CCs. Methods Members Turkish Infectious Diseases Clinical Microbiology Specialization...
The characteristics, diagnosis, and treatment stages of malaria in Turkey the last ten years are not known except few case reports. We aimed to describe details diagnosis practices cases various hospitals across between 2012 2023 after declaration elimination malaria. collected patient data from 30 centers by using Qualtrics Survey Software. patients were categorized according WHO Malaria Severe Disease Symptoms guidelines. detected 299 cases. Of these patients, 23.7 % experienced...
Aim. The use of erythrocyte sedimentation rate (ESR) in coronavirus disease 2019 (COVID-19) to determine severity and prognosis is limited. This study aimed interrogate the diagnostic prognostic role ESR compared other acute-phase reactants. Method. retrospective cross-sectional included 493 confirmed hospitalized adult COVID-19 patients. Pneumonia, radiological severity, oxygen, intensive care requirements, mortality, ESR, reactant values were recorded. Logistic regression ROC analysis...
To evaluate the safety and efficacy of switching from intravenous (IV) to oral antimicrobial therapy in patients with Enterobacterales bacteraemia, after completion 3-5 days microbiologically active IV therapy.
Chronic lymphocytic leukemia (CLL) is a common hematological neoplasm in adults with an abnormal increase monoclonal B lymphocytes.Ibrutinib small molecule class oral cancer drug that inhibits Bruton's tyrosine kinase (BTK) enzyme.They are widely used for treating CLL.Ibrutinib suppresses peripheral lymphocytes, causing both lymphopenia and neutropenia.It has little effect on serum immunoglobulin levels reportedly does not cause reactivation of tuberculosis or opportunistic...
Zoonotic diseases, which are a major public health problem in our city, have negative impact on and also cause economic losses due to yield of animals deaths. This study was carried out determine the seroprevalence tularemia, bartonellosis, brucellosis, Q fever, cystic echinococcosis risk groups for zoonotic infection.Ninety serum samples were taken from people covering veterinarian, butchers, farmers examined with following tests: Microagglutination test indirect fluorescent antibody (IFAT)...
Thymosin beta‐4 ( Tβ 4 ) is a major actin‐sequestering molecule that contributes to cell growth, differentiation, motility, survival, mitosis and angiogenesis. It overexpressed in certain type of carcinoma fibrosarcoma lines associated with metastatic potential. The aim this study was investigate the relationship between expression clinicopathologic features VEGF status gastrointestinal stromal tumors GISTs ). Retrospectively, 60 were re‐examined immunohistochemistry for performed. Increased...
Chronic hepatitis C (CHC) is now a more curable disease with new direct acting antivirals (DAA). Although high sustained virologic response rates, failures still occur in DAA regimens. Our objective this study was to characterize the real-life presence of clinically relevant resistance - associated substitutions (RASs) HCV NS5A gene CHC patients whose regimen has failed.The enrolled 53 who experienced failure as prospective longitudinal cohort between 2017-2019. Genotypic testing performed...
Abstract Background Brucellosis is one of the most common zoonotic diseases in world. Osteoarticular complications, especially vertebral system involvement, are commonly reported. However, reports and coreports pulmonary complications thoracal spondylodiscitis epidural abscess rare. Case presentation Spondylodiscitis was detected at T11–12 level, followed by paravertebral abscess, then empyema a 17-year-old Asian female patient without any additional disease. The had used various antibiotics...
Acinetobacter baumannii strains, are opportunistic pathogens that cause severe nosocomial infections difficult to treat due development of resistance multiple antibiotics. As the antibiotic choices be used in treatment limited, combinations a variety antibiotics used. The aims this study were identify minimal inhibitory concentration (MIC) values colistin and sulbactam against A.baumannii isolates determine vitro activity colistin-sulbactam combination. A total 50 strains isolated from...
Background/Aims: The present study aimed to determine the changes in epidemiology of hepatitis recent years an adult Turkish population.Materials and Methods: Overall, 852 patients with acute viral from 17 centers were included this study.Their sociodemographic characteristics, clinical courses, treatments, laboratory findings retrospectively analyzed.Results: most commonly found microorganisms B virus (55.2%) A (37.6%), types differed significantly according age group (p≤0.001).The...
ÖZET Çocukluk çağı akut gastroenteritlerinden sorumlu viral etkenler hastaların yaş gruplarına ve yaşadıkları bölgenin iklim özelliklerine göre farklılıklar gösterebilmektedir
Resistance to β-lactams in Enterobacteriaceae has been increasing worldwide. This study aimed determine the frequency of β-lactamase genes and antibiotic resistance rates 140 extended-spectrum (ESBL)-producing Escherichia coli isolates obtained from urinary tract infection Ordu Province, Turkey. Isolates were identified by classic methods automated system. ESBL production was confirmed double disk synergy test antimicrobial susceptibility investigated diffusion method. All screened for...
Malaria is still an important public health problem both in Turkey and worldwide. In this research, we examined the epidemiology of malaria using data provided by Control Unit Infectious Disease Division Ordu Health Directory, from years 2002 to 2011.The retrospective study was performed on Provincial Directory. The cases were evaluated according age groups, gender, locations, months parasite species.In last 10 year period, a total 31,575 blood samples 6 (0.02%) detected. Positive all...
Objectives:The role of endoplasmic reticulum (ER) stress in the pathogenesis hepatitis B virus (HBV) has been reported.However, serum levels glucose-regulated protein (GRP) 78 which is an ER marker both tissue and circulation have not reported yet.This study aimed to evaluate GRP78 patients with chronic HBV infection.Materials Methods: A total 60 infection 50 control subjects were included this study.According HBV-DNA levels, subdivided into low, mild high subgroups (n=20, each).Serum level...
Hepatit A virus (HAV) infeksiyonu dunyada ve ulkemizde yaygin olarak gorulen onemli bir halk sagligi sorunudur. Ciddi morbidite mortalite nedeni olabilen hastaligin yayginligi sosyo-ekonomik kosullarla cevresel faktorlerle yakindan iliskilidir. Bu calismada Eylul 2009-Eylul 2010 tarihleri arasinda Unye Devlet Hastanesi’ne basvuran cesitli nedenlerle anti-HAV IgG tetkiki istenen toplam 728 hastanin sonuclari retrospektif degerlendirilmistir. Toplam olgunun 412’si kiz, 316’si erkek olup, total...
Amaç: Ülkemizde sık görülen hepatit B virüsü enfeksiyonu, ciddi bir halk sağlığı sorunu olmasının yanı sıra, tedavi giderleri ve iş gücü kayıpları nedeniyle ekonomik açıdan da önem taşımaktadır.Hepatit virus enfeksiyonlarında alışılmışın dışındaki serolojik test sonuçları, tanı izlem aşamasında yorumlama zorlukları ileri inceleme değerlendirme gerektiren durumlardır.Bu çalışmada yönünden değerlendirilen hastalarda atipik