- Vaccine Coverage and Hesitancy
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- COVID-19 Clinical Research Studies
- Trace Elements in Health
- SARS-CoV-2 and COVID-19 Research
- Heavy Metal Exposure and Toxicity
- Neurological and metabolic disorders
- Motor Control and Adaptation
- Sarcoidosis and Beryllium Toxicity Research
- Vestibular and auditory disorders
- Glycogen Storage Diseases and Myoclonus
- Advanced MRI Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Food Allergy and Anaphylaxis Research
- Exercise and Physiological Responses
- Migraine and Headache Studies
- Infectious Encephalopathies and Encephalitis
- Genetics and Neurodevelopmental Disorders
- Glioma Diagnosis and Treatment
- Dermatology and Skin Diseases
- Metabolism and Genetic Disorders
- Medical Imaging and Pathology Studies
- Neural and Behavioral Psychology Studies
- Trigeminal Neuralgia and Treatments
Istanbul University-Cerrahpaşa
2010-2023
Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2023
Sağlık Bilimleri Üniversitesi
2022-2023
University of Health Science
2022-2023
Istanbul University
2006-2017
Protective neutralizing antibody titers reduce in time after COVID-19 vaccinations, as individuals who have had COVID-19. This study aimed to evaluate the safety and immunogenicity of CoronaVac TURKOVAC vaccines used a booster dose primary vaccination. double-blind, randomized, controlled, phase II, multicenter included healthy male female adults (18–60 years) were vaccinated with two doses vaccine did not exceed duration at least 90 days maximum 270 from second Among 236 eligible...
AIm: Surgery is a treatment option for medically intractable epilepsy patients.Abnormalities in regional cerebral glucose metabolism, as identified by 18-fluorodeoxyglucose positron emission tomography (FDG-PET) have predictive prognostic value evaluating the outcome of surgery.This study investigated efficacy FDG-PET delineation epileptogenic zone (EZ) comparing its consistency with other diagnostic tools and surgical outcome.mATErIAl mEThOds: We analyzed results 121 consecutive patients...
ABSTRACT Lafora disease is a rare, fatal, autosomal recessive progressive myoclonic epilepsy. The condition characterised by seizures, myoclonus and dementia. In this case report, patient who presented with generalised tonic‐clonic seizures at the age of 30 discussed. Until 48, did not have jerks or ataxia clinically, but had well controlled seizures. He developed dementia late extrapyramidal signs. Axillary skin biopsy revealed typical inclusion bodies. Genetic analysis showed mutation in...
In many types of itch, the interaction between immune system cells, keratinocytes, and sensory nerves involved in transmission itch is quite complex. Especially for patients with chronic itching, current treatments are insufficient, their quality life deteriorates significantly.In this study, we aimed to investigate role heat shock protein 90 (Hsp90) inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG), cannabinoid agonist WIN 55,212-2, nitric oxide (NO) synthase Nω-nitro-L-arginine...
The immunogenicity of vaccines decreases over time, causing a need for booster doses. This study aimed to present the long-term (Day 84) results double-blind, randomized, controlled, phase II Hybrid COV-RAPEL TR Study (NCT04979949), in which TURKOVAC or CoronaVac were used as after second dose primary vaccination with CoronaVac. A total 190 participants from Study, who had both Day 28 and 84 results, included. on 84, regarding neutralizing antibody positivity (Wuhan Delta variants)...
Abstract Objectives Hyperhomocysteinemia (HHcy) a significant risk factor for vascular disease, often emerges in epilepsy with the use of antiepileptic drugs. In this relationship, our study investigates combined effects HHcy and antiepileptics on function using rat model. Methods Fourty two rats were included divided into six groups as, 1-Control, 2-L-Met, 3-LEV injected, 4-LEV-injected + L-Met, 5-VAL-injected, 6-VAL injected L-Met. L-Methionine (L-Met) was added to drinking water 1 month...