A5006394471- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- COVID-19 Clinical Research Studies
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Long-Term Effects of COVID-19
- Cardiac Valve Diseases and Treatments
- Pancreatitis Pathology and Treatment
- Heart Failure Treatment and Management
- Inflammation biomarkers and pathways
- Cardiac Structural Anomalies and Repair
- Cardiac tumors and thrombi
- Cardiovascular Disease and Adiposity
- Cardiomyopathy and Myosin Studies
- Cardiac Arrest and Resuscitation
- Cardiovascular Effects of Exercise
- Galectins and Cancer Biology
- Cardiovascular Syncope and Autonomic Disorders
- Coronary Artery Anomalies
- COVID-19 and healthcare impacts
- Biomarkers in Disease Mechanisms
Ministry of Health
2014-2025
Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi
2019-2024
Istanbul University-Cerrahpaşa
2022-2024
Istanbul Medeniyet University
2019-2024
Istanbul University
2015-2023
Sivas State Hospital
2017-2020
Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi
2019-2020
University of Rochester Medical Center
2020
Okmeydanı Eğitim ve Araştırma Hastanesi
2019
Taksim German Hospital
2018-2019
A new infectious outbreak sustained by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now spreading all around the world. The aim of this study was to evaluate prognostic value left ventricular global longitudinal strain (LV-GLS) and right (RV-LS) in patients with disease 2019 (COVID-19). In prospective, single-center study, data were gathered from treated for COVID-19 between April 15 30, 2020. Two-dimensional echocardiography (2-DE) speckle tracking (STE) images obtained...
Objective COVID-19 is a disease with high mortality, and risk factors for worse clinical outcome have not been well-defined yet. The aim of this study to delineate the prognostic importance presence concomitant cardiac injury on admission in patients COVID-19. Methods For multi-center retrospective study, data consecutive who were treated between 20 March April 2020 collected. Clinical characteristics, laboratory findings outcomes obtained from electronic medical records. In-hospital was...
Objective Current guidelines recommend the use of glycoprotein IIb/IIIa (GpIIb/IIIa) inhibitors in patients with ST-segment elevation myocardial infarction (STEMI) only as a bail-out therapy. However, drug penetration to jeopardised area may not be achieved due impeded blood flow and increased microvascular resistance. Aim our study is investigate impact distal intracoronary GpIIb/IIIa inhibitor agent infusion STEMI patients. Primary endpoints were obstruction (MVO) infarct size.
Microvascular disease is considered as one of the main drivers morbidity and mortality in severe COVID-19, microvascular dysfunction has been demonstrated subcutaneous sublingual tissues COVID-19 patients. The presence coronary (CMD) also hypothesized, but direct evidence demonstrating CMD patients missing. In present study, we aimed to investigate hospitalized with understand whether there a relationship between biomarkers myocardial injury, strain inflammation CMD.39 that were 40 control...
Background The contribution of functionally disturbed coronary autoregulation and structurally impaired microvascular vasodilatory function to reduced flow velocity reserve, reflecting microcirculation in diabetes mellitus ( DM ), has not been clearly elucidated. objective this study was identify the mechanism impairment relation duration disease. Methods Results Coronary velocities anterior descending artery were assessed by transthoracic echocardiography following angiography revealing...
Energy drinks (EDs) are widely consumed products of the beverage industry and often chosen by teenagers young adults. Several adverse cardiovascular events malignant cardiac arrhythmias following consumption EDs have been reported in literature. studies suggested that interval from peak to end electrocardiographic T wave (Tp-e) may correspond dispersion repolarization an increased Tp-e Tp-e/QT ratio associated with ventricular arrhythmias. This study investigated acute effects Red Bull ED on...
This study was performed to evaluate the relationship between CHA 2 DS -VASc score and no-reflow (NR) phenomena in patients with non-ST-segment elevation myocardial infarction (NSTEMI). A total number of 428 consecutive NSTEMI were assessed for this study. Patients divided into groups, those NR, NR(+) (n=84), without NR(-) (n=307), according their post-PCI, status. The significantly higher group compared (3.48 ± 1.19 vs 1.81 0.82, P < 0.001). After a multivariate regression analysis, (OR:...
The current knowledge about novel coronavirus-2019 (COVID-19) indicates that the immune system and inflammatory response play a crucial role in severity prognosis of disease. In this study, we aimed to investigate prognostic value systemic biomarkers including C-reactive protein/albumin ratio (CAR), nutritional index (PNI), neutrophil-to-lymphocyte (NLR), lymphocyte-to-monocyte (LMR), platelet-to-lymphocyte (PLR) patients with severe COVID-19.This single-center, retrospective study included...
Two-dimensional (2D) speckle-tracking echocardiographic (STE) imaging is frequently performed in the assessment of cardiovascular diseases. We aim to investigate role global and territorial longitudinal strain (GLS TLS) values assessed via 2D STE detect significant coronary artery disease (CAD) non-ST-segment elevation myocardial infarction (NSTEMI) patients without wall-motion abnormalities.This study enrolled 150 with diagnosis NSTEMI. Patients who had typical chest pain unstable angina...
Abstract Background Although previous studies reported frequent premature atrial contractions(fPACs) increased the risk of adverse cardiovascular outcomes, especially fibrillation(AF), there is a substantial inconsistency between reports concerning definition fPAC. In this study, we aimed to investigate relationship fPAC and AF. We further searched for cutoff value prediction Methods retrospectively analyzed ambulatory 24‐hr Holter monitoring records 392 patients included. Frequent PAC was...
Abstract Background Mitral annular disjunction (MAD) is a structural abnormality characterized by the systolic detachment of posterior mitral annulus and ventricular myocardium. It usually observed coexistent with valve prolapse (MVP) associated mechanical dysfunction despite preserved electrical isolation function annulus. This study aimed to evaluate left (LV) using speckle tracking echocardiography in MVP patients MAD. Methods was designed as prospective, single‐center including 103 40...
Coronavirus disease-19 (COVID-19) is a multisystemic disease that can cause severe illness and mortality by exacerbating symptoms such as thrombosis, fibrinolysis, inflammation. Plasminogen activator inhibitor-1 (PAI-1) plays an important role in regulating fibrinolysis may thrombotic events to develop. The goal of this study examine the relationship between PAI-1 levels severity relation COVID-19.A total 71 hospitalized patients were diagnosed with COVID-19 using real time-polymerase chain...
Background Intramyocardial edema and hemorrhage are key pathological mechanisms in the development of reperfusion-related microvascular damage ST-segment-elevation myocardial infarction. These processes may be facilitated by abrupt restoration intracoronary pressure flow triggered primary percutaneous coronary intervention. We investigated whether pressure-controlled reperfusion via gradual reopening infarct-related artery limit injury patients undergoing Methods Results A total 83 with...
A systemic inflammatory reaction is a common feature of both sarcoidosis and atherosclerosis. Endothelial-cell specific molecule 1 (endocan) marker vascular pathology which also shows correlation with inflammation, endothelial dysfunction, The objective this study was to evaluate the involvement in using serum endocan levels brachial artery flow-mediated dilation (FMD), dysfunction. We included 53 patients without conventional cardiovascular risk factors 40 healthy controls. Endothelial...
Type 1 cardiorenal syndrome (CRS) is an acute renal failure in patients with decompensated heart incidence of 24% to 45%. The aim our study was investigate the significance new biomarkers predict type CRS.The included 111 diagnosed at Istanbul Medical Faculty Emergency Department between 2014 and 2016, 24 healthy volunteers. All urine samples were stored -80°C after centrifugation. Samples run according instructions TIMP-2, ILGF-7, KIM-1, IGFBP-7 ELISA kits. Diuretic treatments then...
Abstract Aim Current literature lacks a definitive threshold of idiopathic premature ventricular complex (PVC) burden for predicting cardiomyopathy (CMP). The main objective the present study was to evaluate relationship between PVC and left ejection fraction (LVEF). Method This multicenter, cross‐sectional included 341 consecutive patients with more than 1,000 in 24 hr Holter monitoring admitted cardiology clinics January 2019 May nineteen different centers. primary outcome LVEF measured...