A5088599745- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Adipokines, Inflammation, and Metabolic Diseases
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- SARS-CoV-2 and COVID-19 Research
- Inflammation biomarkers and pathways
- Cardiovascular Function and Risk Factors
- Cardiovascular Disease and Adiposity
- COVID-19 and healthcare impacts
- Heart Rate Variability and Autonomic Control
- Adipose Tissue and Metabolism
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Diabetes Management and Research
- Heart Failure Treatment and Management
- Sepsis Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Apelin-related biomedical research
- Acute Kidney Injury Research
- Atrial Fibrillation Management and Outcomes
- Regulation of Appetite and Obesity
- Blood Pressure and Hypertension Studies
- Coronary Interventions and Diagnostics
- Inflammatory Biomarkers in Disease Prognosis
Istanbul University
2016-2025
Istanbul Eye Hospital
2022
Sağlık Bilimleri Üniversitesi
2019-2021
Okmeydanı Eğitim ve Araştırma Hastanesi
2011-2020
Bezmialem Foundation University Medical Faculty Hospital
2008-2011
Yedikule Teaching Hospital
2002
Social Security Children's Hospital
2001
Cardiovascular Research Center
2000
Endothelial-specific molecule 1 (endocan) is expressed in endothelial cells. We investigated the relationship between acute coronary syndrome (ACS) and serum endocan levels. included 30 individuals as a control group 53 patients diagnosed with ACS. The severity of artery disease was assessed by modified Gensini stenosis SYNTAX scoring system. There significant difference levels ACS (0.75 ± 0.13 vs 0.86 0.25 ng/mL, P = .014). also diabetic nondiabetic (1.02 0.33 0.81 0.21 .016). no...
COVID-19 caused by the SARS-CoV-2 continues to spread rapidly across world. In our study, we aim investigate relationship between liver enzymes on admission (AST, ALT, ALP, GGT) and severity of COVID-19. We evaluated course disease, hospital stay, damage mortality.Our study included 614 patients who were hospitalized with diagnosis 03.16.20 05.12.20. Patients hematological solid organ malignancy metastases excluded, resulting in 554 met inclusion criteria. retrospectively transaminase...
Abstract Purpose To improve prescribing in older adults, criterion sets have been introduced from different countries. While current are useful to some extent, they do not meet the need European Turkish inappropriate medication use elderly (TIME) criteria was planned this need. Methods In phase 1, user friendly sets: STOPP/START version2 and CRIME were combined. National experts composed of geriatricians non-geriatricians invited review comment. 2, thorough literature performed...
Background and aim Pancytopenia is a clinical condition characterized by the simultaneous reduction of red blood cells, white platelets. It generally arises from conditions associated with bone marrow dysfunction or increased peripheral consumption cells. Understanding regional etiological models pancytopenia paramount importance for optimizing diagnostic therapeutic strategies specific to local population. This study aimed identify causes examine distribution incidence rates in patients...
Introduction: Acute enteritis can occur due to numerous bacterial, viral, and parasitic infections. This clinical condition have various spectra in vulnerable patient groups with immunodeficiency inflammatory bowel disease. study aimed examine cases of acute the emergency unit a tertiary-care hospital. Material Methods: cohort was conducted consecutive patients between September 2022 November 2023. The clinical, laboratory, microbiological data 194 were retrospectively examined. Patients...
Oxidative stress has been implicated in over 100 disorders recent years; however, the situation restless legs syndrome (RLS) not studied yet.Fifty patients with RLS medicated for and 50 sex- age-matched, healthy controls no pathology except mild iron deficiency or anaemia were enrolled. Patients secondary other than excluded. Total oxidant status (TOS), total antioxidant (TAS), oxidative index (OSI), arylesterase (ARE), paraoxonase (PON), stimulated (stim-PON), lipid hydroperoxides (LOOHs),...
Endothelial-specific molecule 1 (endocan) is expressed by endothelial cells and may have a major role in the regulation of cell adhesion pathogenesis inflammatory disorders. We aimed to assess change endocan levels after 3 months lifestyle recommendations guideline-based treatment. Diabetic patients (n = 77) who had neither chronic kidney disease nor were included. After baseline evaluation, advised changes, their medical treatment was determined individually according American Diabetes...
Adropin is a novel marker of metabolic syndrome and insulin resistance. The aim this study was to explore the association serum adropin levels with hepatosteatosis among adult patients.Serum biochemical parameters including liver renal function tests, levels, were compared between patients nonalcoholic fatty disease (NAFLD) healthy control cases.A total 51 mean age 37.9 ± 9.96 years diagnosed grade 2-3 30 cases 34.8 9.5 included in study. Serum NAFLD group statistically significantly lower...
We aimed to investigate the metabolic effects of HIIT exercise on PCOS patients and how it affects adiponectin, vaspin leptin.Twenty women with were included in study divided into two groups. program was applied for 10 Medium Intensity Continuous Training (MICT) other PCOS. At beginning at end study, total cholesterol, low-density lipoprotein cholesterol (LDL-C), high density (HDL-C), triglyceride(TG), insulin, Adiponectin, Leptin, Vaspin levels both groups evaluated.When by performed 12...
Hypertension is a common and important public health problem in Turkey worldwide. Recommendations on the diagnosis treatment of hypertension have been presented many nationally internationally agreed European American guidelines. However, there are differences among these guidelines, some recommendations not consistent with clinical practice our country. Consensus report preparation, participation relevant associations, was considered necessary to merge by evaluating guidelines from...
Acute kidney injury (AKI) in COVID-19 patients is associated with poor prognosis. However, the incidence, risk factors and potential outcomes of AKI hospitalized are not well studied. This a retrospective cohort study conducted two major university hospitals. Electronic health records patients, 18 years or older, between 13 April 1 June 2020 confirmed were reviewed. We described incidence for development patients. Furthermore, we investigated effects on length hospital intensive care unit...
Orlistat is a pancreatic lipase inhibitor which used to treat obesity. Due the increasing prevalence of obesity, orlistat use thought rise progressively. We report an interesting case caused by caught in early stages acute pancreatitis through imaging; addition, had significantly elevated serum amylase levels. A 54-year-old male who history treatment started 7 days before was admitted emergency department with complaints abdominal pain, nausea and vomiting lasting for 24 h. Abdominal...
Thrombotic and embolic complications in the cardiovascular system are evident associated with worse prognosis coronavirus disease 2019 (COVID-19) patients. Endothelial-specific molecule 1 (endocan) plays a role vascular pathology. We hypothesized serum endocan levels on admission primary composite end point (mortality intensive care unit hospitalization) COVID-19 Patients (n = 80) laboratory, clinical, radiological confirmed were included this cross-sectional study. Ten milliliter of...
Myocardial injury caused by COVID-19 was reported in hospitalized patients previously. But the information about cardiac consequences of after recovery is limited. The aim study comprehensive echocardiography assessment right ventricular (RV) recovered from COVID-19. This a prospective, single-center study. After COVID-19, performed consecutive 79 that attended follow-up visits July 15 to November 30, 2020. According at home vs hospital, were divided into two groups: (n = 43) and hospital...
Background: Supraventricular tachyarrhythmia is a common problem in chronic obstructive pulmonary disease (COPD) patients. The purpose of this study to analyze the factors associated with paroxysmal atrial fibrillation (AF) COPD Methods: Forty patients (38 male, 2 female, mean age 60 ± 9 years) and 33 healthy controls (29 4 age: 58 10 were included study. Echocardiography, 24‐hour ambulatory 12‐lead ECG, function tests, arterial blood gases, serum electrolytes measured. On maximum (P max )...
Objectives To evaluate the effect of adjunct treatment with Octagam, an intravenous immunoglobulin (IVIG) product, on clinical outcomes and biomarkers in critically ill COVID-19 patients.
Older adults have been continuously reported to be at higher risk for adverse outcomes of Covid-19. We aimed describe clinical characteristics and early the older Covid-19 patients hospitalized in our center comparatively with younger patients, also analyze triage factors that were related in-hospital mortality adults. Retrospective; observational study. Istanbul Faculty Medicine hospital, Turkey. 362 laboratory-confirmed from March 11 May 11, 2020. The demographic information; associated...
Background: Autonomic heart rate control is impaired after CABG. The aim of this study was to establish the temporal pattern change in decrease HRV observed Methods and Results: Twelve patients with coronary artery disease were assessed 24‐hour Holter recordings 2 days before CABG 1 week, 3 months, 6 year, years All time‐domain frequency‐domain parameters decreased precipitately mostly recovered months except mean NN, rMSSD, pNN50. ratio LF HF showed a slight surgery, preoperative values...