Zeki Toprak

ORCID: 0000-0002-7411-3628
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Research Areas
  • Renal Transplantation Outcomes and Treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Liver Disease Diagnosis and Treatment
  • Cardiovascular Disease and Adiposity
  • Renal and Vascular Pathologies
  • Adipose Tissue and Metabolism
  • Psychosomatic Disorders and Their Treatments
  • Organ Donation and Transplantation
  • Mitochondrial Function and Pathology
  • Renal Diseases and Glomerulopathies
  • Muscle and Compartmental Disorders
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Pregnancy and Medication Impact
  • Calpain Protease Function and Regulation
  • Electrolyte and hormonal disorders
  • Clinical Reasoning and Diagnostic Skills
  • Diabetes Treatment and Management
  • Health and Well-being Studies
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Genetic Neurodegenerative Diseases
  • Cell Adhesion Molecules Research
  • Acute Kidney Injury Research
  • Medical Education and Admissions
  • Vasculitis and related conditions
  • Musculoskeletal pain and rehabilitation

Ümraniye Eğitim ve Araştırma Hastanesi
2023-2024

Sağlık Bilimleri Üniversitesi
2020-2024

University of Health Sciences
2022-2023

Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi
2019-2021

Ondokuz Mayıs University
2021

Istanbul University
2021

Okmeydanı Eğitim ve Araştırma Hastanesi
2017-2020

Adropin is a novel marker of metabolic syndrome and insulin resistance. The aim this study was to explore the association serum adropin levels with hepatosteatosis among adult patients.Serum biochemical parameters including liver renal function tests, levels, were compared between patients nonalcoholic fatty disease (NAFLD) healthy control cases.A total 51 mean age 37.9 ± 9.96 years diagnosed grade 2-3 30 cases 34.8 9.5 included in study. Serum NAFLD group statistically significantly lower...

10.1159/000500106 article EN cc-by-nc Medical Principles and Practice 2019-01-01

Objective Activated macrophages (M1-type macrophages) in adipose tissue secrete many proinflammatory cytokines that induce insulin resistance (IR). Oncostatin M (OSM), a member of the interleukin-6 (IL-6) family Gp130 cytokines, plays an important role variety biological functions, including regulation inflammatory responses. Proinflammatory released patients with IR trigger chronic, low-grade reaction blood vessel walls. This inflammator response leads to endothelial damage, which is main...

10.20945/2359-3997000000176 article EN Archives of Endocrinology and Metabolism 2019-09-25

The aim of this study was to determine how often the recommendations Turkish Hypertension Consensus Report are followed, and draw attention report.The demographic information 1000 patients diagnosed with hypertension details antihypertensive medications prescribed at outpatient service a tertiary care hospital were recorded, data compared mean age 62±11 years. In all, 623 (62.3%) women, 377 (37.7%) men. A combination an angiotensin II receptor blocker (ARB) diuretic most frequently observed...

10.5543/tkda.2017.86344 article EN cc-by-nc-nd Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology 2017-01-01

Sorafenib significantly prolonged progression-free survival in patients with iodine-refractory advanced thyroid cancer. The present study was initiated before sorafenib approved Colombia and therefore represents an effort by oncology institution to evaluate its efficacy safety this population.

10.20945/2359-3997000000357 article EN cc-by Archives of Endocrinology and Metabolism 2021-01-01

BackgroundAlthough percutaneous graft biopsy is well defined in patients who underwent open transplantation, there are only a limited number of studies the literature focused on safety robotic transplantation.ObjectiveThe aim was to assess and efficacy method specifically kidney transplantation.MethodsFrom 2013 2017, we retrospectively analysed records due acute dysfunction. The cohort divided into two groups: individuals transplantation those transplantation.Results85 were included study....

10.2139/ssrn.4809144 preprint EN 2024-01-01

New-onset diabetes after transplantation (NODAT) is a serious complication following solid organ transplantation. NODAT occurs in 2.5% to 40% of all transplant recipients. The identification high-risk patients and the implementation measures limit development can improve long-term prognosis patients. present study aimed assess frequency risk factors kidney Methods. A cohort 103 was included this retrospective single-center study, excluding 31 with pre-existing diabetes. remaining 72 were...

10.31450/ukrjnd.2(82).2024.06 article EN cc-by-sa Ukrainian Journal of Nephrology and Dialysis 2024-02-27

Objective: The objective of this study was to investigate the safety and efficacy percutaneous graft biopsy, specifically in patients who have undergone robotic kidney transplantation, a topic that has received limited attention existing literature. While biopsy is well established open its application transplantation remains relatively unexplored. Material Methods: A retrospective analysis conducted on patient records spanning from 2013 2024, focusing those underwent due acute dysfunction....

10.3390/jcm13154518 article EN Journal of Clinical Medicine 2024-08-02

We present an unusual etiology of primary renal allograft dysfunction attributed to myeloma cast nephropathy in a patient with no history multiple before kidney transplant. The patient, 54-year-old woman, had been on hemodialysis for 6 months transplant presumed diabetic nephropathy; she developed graft immediately after Graft biopsy specimens were consistent nephropathy, and was treated bortezomib, cyclophosphamide, dexamethasone. She achieved complete hematological response regained...

10.6002/ect.2023.0155 article EN Experimental and Clinical Transplantation 2024-07-01

Aim: Alexithymia is a disorder associated with difficulty in recognizing and expressing feelings, which can lead to an increased susceptibility disease development that makes alexithymia possible risk factor for chronic kidney (CKD). This study was performed evaluate pre-dialysis CKD end-stage renal patients undergoing hemodialysis.Material Method: The conducted the Nephrology Outpatient Department Hemodialysis unit of Ümraniye Research Training Hospital. had have diagnosis CKD. Demographic...

10.38053/acmj.1192825 article EN Anatolian Current Medical Journal 2023-01-20

Objective: In inflammatory bowel disease (IBD), there is no reliable biomarker, yet. We aimed to determine whether Serum Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) could be useful as a marker for the diagnosis and/or determination of activity in patients with IBD. Material and Method: A total 47 ulcerative colitis (UC) 25 Crohn’s (CD) were prospectively enrolled. Clinical was analyzed using Disease Activity Index (CDAI) CD Truelove-Witts index UC. Results: sTREM-1...

10.26650/iuitfd.2020.0090 article EN cc-by-nc Journal of Istanbul Faculty of Medicine / İstanbul Tıp Fakültesi Dergisi 2021-07-05

Abstract Background and Aims The most important determinant of renal patient survival in anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is early initiation immunosuppressive (IS) therapy. Other factors with are age function and/or involvement at diagnosis. prognosis poor patients AAV who do not receive IS treatment. effect plasma exchange (PE). underwent plasmapheresis treatment has been questioned recent studies. Renal histology a predictor long-term risk failure...

10.1093/ndt/gfad063a_3266 article EN Nephrology Dialysis Transplantation 2023-06-01

Objectives: In this study, we aimed to research the frequency of musculoskeletal manifestations patients receiving hemodialysis treatment, and evaluate relationship between quality life these patients. Methods: Patients undergoing for at least 6 months were included in our study. asked complete a questionnaire that formed by investigators including demographic, clinical features, symptoms frequently seen who receive hemodialysis. Kidney Disease Quality Life Short Form Version 1.3 (KDQOL-SF...

10.18621/eurj.1267147 article EN The European Research Journal 2023-05-29

Abstract Background and Aims The recipients who have antibodies againts to donors’ HLA (Anti HLA- DSA) carrie a huge risk for allograf (AG) losing. In current study, it was retrospectively evaluated whether the live donor kidney (LDKRs) under desensitization (DS) were exposed more AG loss, lower survival complications. Method 17 of 269 LDKRs had high anti-HLA DSA found prior transplantation (KTX). DS performed with plasmapheresis (PF) rituximab (RTX) before KTX. order determine risks DS, not...

10.1093/ndt/gfaa142.p1787 article EN Nephrology Dialysis Transplantation 2020-06-01
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