Okan Dikker

ORCID: 0000-0002-9153-6139
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Adipokines, Inflammation, and Metabolic Diseases
  • Gout, Hyperuricemia, Uric Acid
  • Adipose Tissue and Metabolism
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipid metabolism and disorders
  • Hemoglobinopathies and Related Disorders
  • Cardiovascular Disease and Adiposity
  • Inflammasome and immune disorders
  • Trace Elements in Health
  • Vitamin D Research Studies
  • Alkaline Phosphatase Research Studies
  • Galectins and Cancer Biology
  • Diet and metabolism studies
  • Bone health and osteoporosis research
  • Bone and Joint Diseases
  • Inflammatory Biomarkers in Disease Prognosis
  • Dermatology and Skin Diseases
  • Bariatric Surgery and Outcomes
  • Urticaria and Related Conditions
  • Ear Surgery and Otitis Media
  • Epilepsy research and treatment
  • Iron Metabolism and Disorders
  • Pregnancy and preeclampsia studies
  • Birth, Development, and Health

Sağlık Bilimleri Üniversitesi
2019-2024

University of Health Sciences Antigua
2020-2024

Izmir University
2021-2023

Okmeydanı Eğitim ve Araştırma Hastanesi
2016-2021

University of Health Sciences
2019-2021

Hitit Üniversitesi Çorum Eğitim ve Araştırma Hastanesi
2018-2019

University of Health Science
2019

Ankara Fizik Tedavi ve Rehabilitasyon Eğitim ve Araştırma Hastanesi
2019

Ministry of Health
2019

Istanbul University
2017

The atherogenic index of plasma (AIP) is the base-10 logarithmic conversion triglyceride to high-density lipoprotein cholesterol ratio [AIP = log10 (triglyceride/HDL cholesterol)]. Some studies have found a link between low serum vitamin D levels, AIP, and fatty liver. This study was conducted evaluate relationship AIP liver, levels in obese adolescents aged 10-17 years.This included 136 adolescents, including 83 53 healthy controls, age range years. Thirty-nine had livers. Those with...

10.3390/children10040641 article EN cc-by Children 2023-03-29

Adropin is a novel marker of metabolic syndrome and insulin resistance. The aim this study was to explore the association serum adropin levels with hepatosteatosis among adult patients.Serum biochemical parameters including liver renal function tests, levels, were compared between patients nonalcoholic fatty disease (NAFLD) healthy control cases.A total 51 mean age 37.9 ± 9.96 years diagnosed grade 2-3 30 cases 34.8 9.5 included in study. Serum NAFLD group statistically significantly lower...

10.1159/000500106 article EN cc-by-nc Medical Principles and Practice 2019-01-01

Studies have shown that serum uric acid levels and acid-related ratios, such as acid-to-albumin ratio (UAR), acid-to-creatinine (UCR), acid-to-high-density lipoprotein cholesterol (HDL cholesterol) (UHR), acid-to-lymphocyte (ULR), are associated with various diseases their complications, these ratios can be used biomarkers. In the current study, we aimed to investigate in obese adolescents relationship of insulin resistance obesity for first time literature.A total 100 (60 40 healthy) aged...

10.3390/children10091493 article EN cc-by Children 2023-08-31

Aim: Galectin-3 affects inflammation, cell adhesion, proliferation, differentiation and angiogenesis. Upon examining the pathogenesis of obesity functions galectin-3, we thought that galectin-3 may play a significant role in obese patients. This study aims to evaluate relationship between obesity, insulin resistance levels. Methods: Eighty five patients aged 18-50 years were included this cross-sectional study. BMI>30 considered obese, those 25-30 18-25 overweight normal weight,...

10.28982/josam.602984 article EN Journal of Surgery and Medicine 2019-08-14

Abstract Introduction Crosstalk between bone and adipose tissues is implicated in several pathologic conditions related to metabolism. Omentin-1, a 34-kD protein, released from omental tissue. A few studies indicated the effect of omentin-1 on health mineral density (BMD) interaction with vitamin D. Therefore, this study aimed investigate relationship omentin-1, D, BMD postmenopausal women osteoporosis compared non-osteoporotic counterparts. Materials methods Forty (OP), 40 counterparts...

10.1055/s-0043-120110 article EN Experimental and Clinical Endocrinology & Diabetes 2017-11-08

Introduction: Obesity is a gradually more important multifactorial disease in both children and adults. Obese adolescents are at higher risk of becoming obese adulthood, which associated with an increased mortality morbidity. There subclinical systemic inflammation obesity. The study aimed to evaluate the hematological parameters as indicator show relationship monocyte/HDL-cholesterol ratio, having lipid component, other inflammatory parameters. Materials methods: We retrospectively reviewed...

10.53986/ibjm.2022.0002 article EN cc-by Iberoamerican Journal of Medicine 2021-11-11

Objective: Postmenopausal osteoporosis a disease with increased fracture tendency in the bones based upon reduced bone mineral density.Oxidative stress is an important risk factor for osteoporosis.In our study, it was aimed to investigate levels of oxidative markers women postmenopausal osteoporosis.Materials and Methods: In without also healthy controls; density, routine laboratory tests, 25-hydroxyvitamin D 3 , malondialdehyde, protein carbonyl total antioxidant capacity were...

10.4274/tod.71501 article EN Turkish Journal of Osteoporosis 2018-07-26

Background: Febrile seizures are defined as associated with a febrile illness that developed without central nervous system infection or acute electrolyte imbalance, intoxication, trauma, and metabolic disorder in children aged 1 month to 5 years previous afebrile seizures. Various studies show relationship between zinc levels Objectives: The purpose of this study was examine the serum Methods: This prospective, cross-sectional, descriptive conducted from 04/10/2021 04/02/2022. A total 85 6...

10.5812/ijp-132778 article EN Iranian Journal of Pediatrics 2023-08-03

Therapeutic drug monitoring (TDM) involves the measurement of concentrations in serum, plasma, whole blood, or other biologic fluids. This study focused on evaluating TDM requests a city hospital over period one year, retrospectively.

10.7754/clin.lab.2024.231223 article EN Clinical Laboratory 2024-01-01

Do Cytokines Play a Role in Chronic Spontaneous Urticaria Childhood?IL-17 One of Them?Çocukluk Çağındaki Kronik Spontan Ürtikerde Sitokinlerin Rolü Var mı? IL-17 Bunlardan Biri mi

10.4274/bmj.galenos.2023.2022.12-6 article TR Bakirkoy Tip Dergisi / Medical Journal of Bakirkoy 2024-06-28

Do Cytokines Play a Role in Chronic Spontaneous Urticaria Childhood?IL-17 One of Them?Çocukluk Çağındaki Kronik Spontan Ürtikerde Sitokinlerin Rolü Var mı? IL-17 Bunlardan Biri mi

10.4274/bmj.galenos.2023.2022.126 article TR Bakirkoy Tip Dergisi / Medical Journal of Bakirkoy 2024-07-16

Objective: We examined the association between uric acid and glycemic status by aspects of age sex. Methods: The retrospective was performed study at Okmeydanı Educate Research Hospital. All data were obtained from patient records. Only one sam­ple HbA1c or glucose measurement within a year included. To evaluate pattern control, we categorized patients according to levels grouped them range values. measured high performance liquid chromatography, routine biochemistry parameters determined...

10.5799/jcei.328707 article EN Journal of Clinical and Experimental Investigations 2016-03-01

Aim: Vitamin B12 is naturally obtained from animal-derived foods and important for the development wellbeing of babies.Vitamin deficiency a general health concern in developing countries.This study aimed to investigate effects different feeding practices on vitamin levels hemogram parameters infants aged 6-9 months. Materials Methods:A total 120 (61 boys, 59 girls) months were retrospectively evaluated.These babies assigned three groups according practices: 1) only breast milk, 2) milk...

10.4274/jpr.galenos.2019.00377 article EN cc-by-nc-nd The Journal of Pediatric Research 2019-02-27

10.5281/zenodo.7855676 article EN cc-by Zenodo (CERN European Organization for Nuclear Research) 2023-04-24

<b>Objectives:</b> Omentin-1, an adipocytokine that increases the insulin sensitivity, has been determined to be reduced in patients with resistance, impaired glucose tolerance, and Type-2 diabetes mellitus. In this study, we have investigated alterations Omentin-1 levels blood regulation diabetic having poor glycemic control. By way, aimed determine role of as a marker follow-up monitoring progression diabetes. <b>Methods:</b> Totally 58 type 2 mellitus, older than 18 years age who were...

10.1055/s-0042-118862 article EN Experimental and Clinical Endocrinology & Diabetes 2017-01-10

Amaç: Helikobakter pilori pozitifliği, ülkemizde ve dünyada&#x0D; yüksek prevalansa sahip olup kronik gastrit, peptik ülser, mukoza ile ilişkili&#x0D; lenfoid doku lenfoması gastrik adenokarsinomla ilişkili bulunmuştur.&#x0D; yaygın olarak görülmesi geniş bir patolojik&#x0D; spektrumu olması nedeniyle halk sağlığı açısından önemlidir. Çalışmamızda&#x0D; nötrofil lenfosit oranı ortalama trombosit hacmi helikobakter pilori&#x0D; pozitifliği arasındaki ilişkiyi göstermeyi amaçladık. &#x0D;...

10.5798/dicletip.539924 article TR Dicle Medical Journal / Dicle Tip Dergisi 2019-03-14

Aims: Hypothyroidism is the most commonly encountered hormone deficiency determined in all age groups. Serum galectin-3 concentrations that play important roles cellular proliferation and adhesion were not studied before hypothyroidism. In this study, we aimed to determine relationship between serum hypothyroidism.Methods: A total of 83 individuals, 46 patients with hypothyroidism 37 healthy controls, included study. Among hypothyroidism, anti-TPO higher than reference range 22 them while it...

10.1080/00365513.2019.1627576 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2019-06-12

Aim: Betatrophin, also known as angiopoietin-like peptide-8, is an adipokine in glycoprotein structure synthesized from adipose tissue and liver. Betatrophin plays a role fat energy metabolism by inhibiting lipoprotein lipase, the key enzyme hydrolysis of plasma lipoproteins. Although thyroid hormones have active metabolism, their relationship with cholesterol lipid not clear. In our study, we aimed to investigate serum betatrophin levels patients overt hypothyroidism.Methods: This...

10.28982/josam.610414 article EN Journal of Surgery and Medicine 2019-09-02

Background: Glypican-4 is an adipose tissue-originated cytokine which enhances insulin signaling through direct interaction with the receptors. Objectives: The aim of this study was to analyze relationship between obesity and serum glipican-4 levels in adolescents. Methods: Our carried out on 80 volunteer adolescents, 49 were obese patients 31 healthy normal weight control cases. adolescents a body mass index (BMI) 95% percentile over defined as terms age sex. Enzyme-Linked Immuno Sorbent...

10.5812/ijp.95355 article EN Iranian Journal of Pediatrics 2019-12-01
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